Type 2 diabetes mellitus and osteoarthritis

• Published in: Seminars in arthritis and rheumatism Vol. 49; no. 1; pp. 9 - 19
• Main Authors: Veronese, Nicola, Cooper, Cyrus, Reginster, Jean-Yves, Hochberg, Marc, Branco, Jaime, Bruyère, Olivier, Chapurlat, Roland, Al-Daghri, Nasser, Dennison, Elaine, Herrero-Beaumont, Gabriel, Kaux, Jean-François, Maheu, Emmanuel, Rizzoli, René, Roth, Roland, Rovati, Lucio C., Uebelhart, Daniel, Vlaskovska, Mila, Scheen, André
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.08.2019; WB Saunders
• Subjects: Diabetes Mellitus, Type 2 - complications; Diabetes Mellitus, Type 2 - metabolism; Disease Progression; Endocrinology and metabolism; Human health and pathology; Humans; Insulin Resistance - physiology; Life Sciences; Obesity; Obesity - complications; Obesity - metabolism; Osteoarthritis; Osteoarthritis - complications; Osteoarthritis - metabolism; Pathophysiology; Rhumatology and musculoskeletal system; Safety; Type 2 diabetes mellitus; Obesity; T2DM; NAFLD; OA; MetS; Pathophysiology; NSAID; Type 2 diabetes mellitus; Safety; Osteoarthritis

Type 2 diabetes mellitus (T2DM) and osteoarthritis (OA) are common diseases that frequently co-exist, along with overweight/obesity. While the mechanical impact of excess body weight on joints may explain lower limb OA, we sought to explore whether T2DM is linked to OA outside of excess weight and w...