The ORF8 protein of SARS-CoV-2 induced endoplasmic reticulum stress and mediated immune evasion by antagonizing production of interferon beta - Rashid, Farooq; Dzakah, Emmanuel Enoch; Wang, Haiying; Tang, Shixing (Virus research, 2021)
Keywords: Activating Transcription Factor 6 - physiology; antagonists; eIF-2 Kinase - physiology; endoplasmic reticulum; Endoplasmic reticulum stress; Endoplasmic Reticulum Stress - physiology; Endoribonucleases - physiology; HEK293 Cells; Humans; Immune Evasion; Interferon beta; interferon regulatory factor-3; Interferon-beta - antagonists & inhibitors; Interferon-beta - biosynthesis; interferons; Open reading frame 8; Open reading frame 8 genotypes; polyinosinic-polycytidylic acid; Protein Serine-Threonine Kinases - physiology; SARS-CoV-2; Sequence Alignment; Severe acute respiratory syndrome coronavirus 2; Signal Transduction - physiology; Unfolded Protein Response; Viral Proteins - chemistry; Viral Proteins - physiology; viruses; X-Box Binding Protein 1 - physiology; Open reading frame 8; SARS-CoV-2; Open reading frame 8 genotypes; Interferon beta; Endoplasmic reticulum stress