Yeast metabolic engineering for hemicellulosic ethanol production

• Published in: Current opinion in biotechnology Vol. 20; no. 3; pp. 300 - 306
• Main Authors: Van Vleet, JH, Jeffries, TW
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.06.2009
• Subjects: Aldehyde Reductase - genetics; Aldehyde Reductase - metabolism; Aldose-Ketose Isomerases - genetics; Aldose-Ketose Isomerases - metabolism; D-Xylulose Reductase - genetics; D-Xylulose Reductase - metabolism; Ethanol - metabolism; Internal Medicine; Pichia - genetics; Pichia - metabolism; Polysaccharides - metabolism; Protein Engineering - methods; Xylose - metabolism; Yeasts - genetics; Yeasts - metabolism

Efficient fermentation of hemicellulosic sugars is critical for the bioconversion of lignocellulosics to ethanol. Efficient sugar uptake through the heterologous expression of yeast and fungal xylose/glucose transporters can improve fermentation if other metabolic steps are not rate limiting. Rectif...