The PmrA‐PmrB two‐component system responding to acidic pH and iron controls virulence in the plant pathogen Erwinia carotovora ssp. carotovora

• Published in: Molecular microbiology Vol. 50; no. 3; pp. 795 - 807
• Main Authors: Hyytiäinen, Heidi, Sjöblom, Solveig, Palomäki, Tiina, Tuikkala, Anne, Tapio Palva, E.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.11.2003
• Subjects: Amino Acid Sequence; Anti-Bacterial Agents - pharmacology; Arabidopsis thaliana; Bacterial Proteins - genetics; Bacterial Proteins - metabolism; Drug Resistance, Bacterial - genetics; Erwinia carotovora; Gene Expression Regulation, Bacterial; Homeostasis; Hydrogen-Ion Concentration; Iron - pharmacology; Magnesium - metabolism; Magnesium - pharmacology; Molecular Sequence Data; Mutation; Operon; Pectobacterium carotovorum - drug effects; Pectobacterium carotovorum - pathogenicity; Pectobacterium carotovorum - physiology; Plant Diseases - microbiology; PmrA protein; PmrB protein; polymyxin B; Polymyxin B - pharmacology; Repressor Proteins - genetics; Repressor Proteins - metabolism; RNA-Binding Proteins - genetics; RNA-Binding Proteins - metabolism; Sequence Homology, Amino Acid; Solanum tuberosum; Transcription Factors - drug effects; Transcription Factors - genetics; Transcription Factors - metabolism; Virulence - genetics

Summary Efficient response to environmental cues is crucial to successful infection by plant‐pathogenic bacteria such as Erwinia carotovora ssp. carotovora. The expression of the main virulence genes of this pathogen, encoding extracellular enzymes that degrade the plant‐cell wall, is subject to com...