Circulating factors associated with sarcopenia during ageing and after intensive lifestyle intervention

• Published in: Journal of cachexia, sarcopenia and muscle Vol. 10; no. 3; pp. 586 - 600
• Main Authors: Li, Chun‐wei, Yu, Kang, Shyh‐Chang, Ng, Li, Guo‐xun, Jiang, Ling‐juan, Yu, Song‐lin, Xu, Long‐yu, Liu, Rong‐ji, Guo, Zi‐jian, Xie, Hai‐yan, Li, Rong‐rong, Ying, Jie, Li, Kang, Li, Dong‐jing
• Format: Journal Article
• Language: English
• Published: Germany John Wiley & Sons, Inc 01.06.2019; John Wiley and Sons Inc; Wiley
• Subjects: Aged; Aging; Aging - blood; Aging - immunology; Body Composition; China; Chronic illnesses; Cognitive ability; Cross-Sectional Studies; Cytokine TWEAK - blood; Cytokine TWEAK - immunology; Cytokines; Diet; Disease; Elderly; Exercise; Female; Gait; Growth factors; Healthy Lifestyle; Hospitals; Humans; Immunoassay; Inflammation; Inflammation - blood; Inflammation - diagnosis; Inflammation - immunology; Inflammation - rehabilitation; Inflammation Mediators - blood; Inflammation Mediators - immunology; Insulin; Intervention; Lifestyle interventions; Lifestyles; Longitudinal Studies; Male; Medical screening; Metabolic hormones; Middle Aged; Muscle strength; Muscle, Skeletal - immunology; Musculoskeletal system; Nutrition research; Older people; Original; Physical fitness; Proinflammatory cytokines; Prospective Studies; Proteins; Resistance Training; Sarcopenia; Sarcopenia - blood; Sarcopenia - diagnosis; Sarcopenia - immunology; Sarcopenia - rehabilitation; Severity of Illness Index; Strength training; Studies; Treatment Outcome; Tumor Necrosis Factor-alpha - blood; Tumor Necrosis Factor-alpha - immunology; Tumor necrosis factor-TNF; Walking; China; Beijing China; United States > US; Lifestyle interventions; Sarcopenia; Inflammation; Proinflammatory cytokines; Elderly; Metabolic hormones

Background Ageing, chronic diseases, prolonged inactivity, and inadequate nutrition pose a severe threat to skeletal muscle health and function. To date, experimental evidence suggests that ageing‐related subclinical inflammation could be an important causative factor in sarcopenia. Although inflamm...