Acoustic enhancement of sleep slow oscillations in mild cognitive impairment

• Published in: Annals of clinical and translational neurology Vol. 6; no. 7; pp. 1191 - 1201
• Main Authors: Papalambros, Nelly A., Weintraub, Sandra, Chen, Tammy, Grimaldi, Daniela, Santostasi, Giovanni, Paller, Ken A., Zee, Phyllis C., Malkani, Roneil G.
• Format: Journal Article
• Language: English
• Published: United States John Wiley & Sons, Inc 01.07.2019; John Wiley and Sons Inc; Wiley
• Subjects: Acoustic Stimulation; Acoustics; Age; Aged; Aged, 80 and over; Aging; Alzheimer's disease; Atrophy; Cognitive ability; Cognitive Dysfunction - physiopathology; Cross-Over Studies; Dementia; Electroencephalography; Health care; Humans; Hypotheses; Memory; Memory Consolidation; Mental Recall - physiology; Middle Aged; Scholarships & fellowships; Sleep apnea; Sleep, Slow-Wave - physiology; United States > US

Objective Slow‐wave activity (SWA) during sleep is reduced in people with amnestic mild cognitive impairment (aMCI) and is related to sleep‐dependent memory consolidation. Acoustic stimulation of slow oscillations has proven effective in enhancing SWA and memory in younger and older adults. In this...