Current Understanding and Management of Medullary Thyroid Cancer

• Published in: The oncologist (Dayton, Ohio) Vol. 18; no. 10; pp. 1093 - 1100
• Main Authors: Roy, Madhuchhanda, Chen, Herbert, Sippel, Rebecca S.
• Format: Journal Article
• Language: English
• Published: Durham, NC, USA AlphaMed Press 01.10.2013
• Subjects: Calcitonin - blood; Carcinoma, Medullary - blood; Carcinoma, Medullary - congenital; Carcinoma, Medullary - genetics; Carcinoma, Medullary - pathology; Carcinoma, Medullary - surgery; Carcinoma, Neuroendocrine; Endocrinology; Familial Medullary Thyroid Cancer (FMTC); Germ-Line Mutation; Humans; Lymph Node Excision; Medullary Thyroid Cancer (MTC); Multiple Endocrine Neoplasia Syndrome; Multiple Endocrine Neoplasia Type 2a - blood; Multiple Endocrine Neoplasia Type 2a - genetics; Multiple Endocrine Neoplasia Type 2a - pathology; Multiple Endocrine Neoplasia Type 2a - surgery; Prophylactic surgery in MTC; Proto-Oncogene Proteins c-ret - genetics; RET proto‐oncogene; Serum calcitonin; Thyroid Neoplasms - blood; Thyroid Neoplasms - genetics; Thyroid Neoplasms - pathology; Thyroid Neoplasms - surgery; Thyroidectomy; Prophylactic surgery in MTC; Familial Medullary Thyroid Cancer (FMTC); Medullary Thyroid Cancer (MTC); RET proto-oncogene; Multiple Endocrine Neoplasia Syndrome; Serum calcitonin

Learning Objectives Identify and evaluate a patient with a diagnosis of medullary thyroid cancer. Utilize genetic testing for the RET proto‐oncogene and explain how the location of the mutation affects the risks for the patient. Select among the surgical treatment options for patients with medullary...