卵巢交界性上皮性肿瘤112例临床分析
目的探讨卵巢交界性上皮性肿瘤的临床特点及影响复发的相关因素.方法回顾性分析天津医科大学总医院2000 年3 月-2015 年1 月收治的112 例卵巢交界性上皮性肿瘤的临床资料.结果112 例患者发病的平均年龄为（50.59±16.90）岁.FIGO 临床分期Ⅰ期102 例（91.07%）,Ⅱ期4 例（3.57%）,Ⅲ期6 例（5.36%）;血清肿瘤标志物检查：行CA125 检查患者102 例,其中指标升高者27 例,占26.47%;112 例患者均进行手术治疗,年轻患者较年长患者更倾向于选择保守手术治疗;随访患者97 例,其中5 例复发,复发病例均行非保留生育功能手术.对不同临床病理因素下复...
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| Published in | 天津医药 Vol. 44; no. 9; pp. 1092 - 1095 |
|---|---|
| Main Author | |
| Format | Journal Article |
| Language | Chinese |
| Published |
天津医科大学总医院妇产科 邮编300052
2016
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| Subjects | |
| Online Access | Get full text |
| ISSN | 0253-9896 |
| DOI | 10.11958/20160056 |
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| Abstract | 目的探讨卵巢交界性上皮性肿瘤的临床特点及影响复发的相关因素.方法回顾性分析天津医科大学总医院2000 年3 月-2015 年1 月收治的112 例卵巢交界性上皮性肿瘤的临床资料.结果112 例患者发病的平均年龄为（50.59±16.90）岁.FIGO 临床分期Ⅰ期102 例（91.07%）,Ⅱ期4 例（3.57%）,Ⅲ期6 例（5.36%）;血清肿瘤标志物检查：行CA125 检查患者102 例,其中指标升高者27 例,占26.47%;112 例患者均进行手术治疗,年轻患者较年长患者更倾向于选择保守手术治疗;随访患者97 例,其中5 例复发,复发病例均行非保留生育功能手术.对不同临床病理因素下复发的病例进行对比,病理提示微浸润患者复发率高于无微浸润患者[37.50%（3/8）vs. 2.25%（2/89）,P=0.004];在浆液性交界性肿瘤患者中,微乳头型交界性浆液性肿瘤的复发率高于非微乳头型[40.00%（2/5）vs. 0（0/41）,P=0.019];7 例行保留生育功能手术的患者成功妊娠.结论对于年轻有生育要求的卵巢交界性上皮性肿瘤患者可选择保留生育功能手术,结局安全有效.对于存在间质微浸润及微乳头型患者要警惕复发的可能. |
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| AbstractList | R737.31; 目的：探讨卵巢交界性上皮性肿瘤的临床特点及影响复发的相关因素。方法回顾性分析天津医科大学总医院2000年3月—2015年1月收治的112例卵巢交界性上皮性肿瘤的临床资料。结果112例患者发病的平均年龄为（50.59±16.90）岁。FIGO临床分期Ⅰ期102例（91.07%），Ⅱ期4例（3.57%），Ⅲ期6例（5.36%）；血清肿瘤标志物检查：行CA125检查患者102例，其中指标升高者27例，占26.47%；112例患者均进行手术治疗，年轻患者较年长患者更倾向于选择保守手术治疗；随访患者97例，其中5例复发，复发病例均行非保留生育功能手术。对不同临床病理因素下复发的病例进行对比，病理提示微浸润患者复发率高于无微浸润患者[37.50%（3/8）vs.2.25%（2/89）， P=0.004]；在浆液性交界性肿瘤患者中，微乳头型交界性浆液性肿瘤的复发率高于非微乳头型[40.00%（2/5）vs.0（0/41），P=0.019]；7例行保留生育功能手术的患者成功妊娠。结论对于年轻有生育要求的卵巢交界性上皮性肿瘤患者可选择保留生育功能手术，结局安全有效。对于存在间质微浸润及微乳头型患者要警惕复发的可能。 目的探讨卵巢交界性上皮性肿瘤的临床特点及影响复发的相关因素.方法回顾性分析天津医科大学总医院2000 年3 月-2015 年1 月收治的112 例卵巢交界性上皮性肿瘤的临床资料.结果112 例患者发病的平均年龄为（50.59±16.90）岁.FIGO 临床分期Ⅰ期102 例（91.07%）,Ⅱ期4 例（3.57%）,Ⅲ期6 例（5.36%）;血清肿瘤标志物检查：行CA125 检查患者102 例,其中指标升高者27 例,占26.47%;112 例患者均进行手术治疗,年轻患者较年长患者更倾向于选择保守手术治疗;随访患者97 例,其中5 例复发,复发病例均行非保留生育功能手术.对不同临床病理因素下复发的病例进行对比,病理提示微浸润患者复发率高于无微浸润患者[37.50%（3/8）vs. 2.25%（2/89）,P=0.004];在浆液性交界性肿瘤患者中,微乳头型交界性浆液性肿瘤的复发率高于非微乳头型[40.00%（2/5）vs. 0（0/41）,P=0.019];7 例行保留生育功能手术的患者成功妊娠.结论对于年轻有生育要求的卵巢交界性上皮性肿瘤患者可选择保留生育功能手术,结局安全有效.对于存在间质微浸润及微乳头型患者要警惕复发的可能. |
| Abstract_FL | Objective To determine the clinical features and the factors affecting the recurrence of ovarian borderline epithelial tumors. Methods A retrospective data of 112 cases with ovarian borderline epithelial tumors admitted in General Hospital of Tianjin Medical University from 2000 to 2015 were analyzed. Results The average age was (50.59±16.90) years in 112 patients with FIGO stageⅠof 102 (91.07%) patients, stageⅡof 4 (3.57%) and stageⅢof 6 (5.36%). The serum tumor marker (CA125) was examined in 102 patients, and 27 cases with the elevated indicator (26.47%). Surgical treatment was performed in 112 patients. Younger patients were more likely to choose conservative surgery. Ninety-seven patients were followed up, and 5 of them relapsed. Non fertility preserving surgery was performed in patients with recurrence. The recurrence rates of patients with different clinical pathological factors were compared. The recurrence rate was higher in patients with micro infiltration than that of patients without micro infiltration [37.50%(3/8) vs. 2.25%(2/89), P=0.004]. And the recurrence rate was higher in patients with microemulsion type borderline serous tumor than that of patients with non-papillary tumors [40.00%(2/5)vs. 0(0/41),P=0.019]. Seven patients underwent conservative surgery had normal spontaneous pregnancy. Conclusion The fertility-sparing surgery can be used as the treatment procedures for young patients, which is safe and effective. It is necessary to be on alert of recurrence for the cases with micropapillary pattern, and microinvasive tumor. |
| Author | 杨文 王颖梅 刘国艳 闫晔 马学功 薛凤霞 |
| AuthorAffiliation | 天津医科大学总医院妇产科,300052 |
| AuthorAffiliation_xml | – name: 天津医科大学总医院妇产科 邮编300052 |
| Author_FL | YANG Wen YAN Ye MA Xuegong XUE Fengxia LIU Guoyan WANG Yingmei |
| Author_FL_xml | – sequence: 1 fullname: YANG Wen – sequence: 2 fullname: WANG Yingmei – sequence: 3 fullname: LIU Guoyan – sequence: 4 fullname: YAN Ye – sequence: 5 fullname: MA Xuegong – sequence: 6 fullname: XUE Fengxia |
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| Copyright | Copyright © Wanfang Data Co. Ltd. All Rights Reserved. |
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| Keywords | ovarian neoplasms 卵巢肿瘤 gynecologic surgical procedures 妇科外科手术 卵巢交界性上皮性肿瘤 预后 epithelialborderline ovarian tumors prognosis |
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| Notes | YANG Wen, WANG Yingmei, LIU Guoyan, YAN Ye, MA Xuegong, XUE Fengxia（Department of Gynecology and Obstetrics, Tianjin Medical University General Hospital, Tianjin 300052, China） ovarian neoplasms; gynecologic surgical procedures; prognosis; epithelialborderline ovarian tumors 12-1116/R Objective To determine the clinical features and the factors affecting the recurrence of ovarian borderlineepithelial tumors. Methods A retrospective data of 112 cases with ovarian borderline epithelial tumors admitted in GeneralHospital of Tianjin Medical University from 2000 to 2015 were analyzed. Results The average age was （50.59±16.90） years in112 patients with FIGO stage Ⅰof 102 （91.07%） patients, stage Ⅱof 4 （3.57%） and stage Ⅲof 6 （5.36%）. The serum tumor marker（CA125） was examined in 102 patients, and 27 cases with the elevated indicator （26.47%）. Surgical treatment was performed in112 patients. Younger patients were more likely to choose conservative surgery. Ninety-seven patients were followed up, and 5of them relapsed. |
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| Snippet | 目的探讨卵巢交界性上皮性肿瘤的临床特点及影响复发的相关因素.方法回顾性分析天津医科大学总医院2000 年3 月-2015 年1 月收治的112 例卵巢交界性上皮性肿瘤的临床资料.结果112 例患者发病的平均年龄为（50.59±16.90）岁.FIGO 临床分期Ⅰ期102 例（91.07%）,Ⅱ期4... R737.31;... |
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| SubjectTerms | 卵巢交界性上皮性肿瘤 卵巢肿瘤 妇科外科手术 预后 |
| Title | 卵巢交界性上皮性肿瘤112例临床分析 |
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