Increased hemoglobin and heme in MALDI-TOF MS analysis induce ferroptosis and promote degeneration of herniated human nucleus pulposus - Shan, Liang; Xu, Ximing; Zhang, Jing; Cai, Peng; Gao, Han; Lu, Yingjie; Shi, Jiangang; Guo, Yinlong; Su, Yue (Molecular medicine (Cambridge, Mass.), 2021)
Keywords: Adolescent; Adult; Aged; Biomarkers; Case-Control Studies; Cells, Cultured; Disc degeneration; Disease Susceptibility; Female; Ferroptosis; Heme - metabolism; Heme iron; Hemoglobins - metabolism; Humans; Intervertebral Disc Displacement - diagnosis; Intervertebral Disc Displacement - etiology; Intervertebral Disc Displacement - metabolism; Lumbar disc herniation; MALDI-TOF MS; Male; Middle Aged; Nucleus Pulposus - metabolism; Nucleus Pulposus - pathology; Prognosis; ROC Curve; Signal Transduction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Vasculogenesis; Young Adult; Heme iron; MALDI-TOF MS; Ferroptosis; Vasculogenesis; Disc degeneration; Lumbar disc herniation