Oncolytic Avian Reovirus σA-Modulated Upregulation of the HIF-1α/C-myc/glut1 Pathway to Produce More Energy in Different Cancer Cell Lines Benefiting Virus Replication - Hsu, Chao-Yu; Huang, Jing-Wen; Huang, Wei-Ru; Chen, I-Chun; Chen, Ming-Shan; Liao, Tsai-Ling; Chang, Yu-Kang; Munir, Muhammad; Liu, Hung-Jen (Viruses, 2023)
Keywords: Analysis; Antibodies; Autophagy; Avian orthoreovirus; avian reoviruses; c-myc; c-Myc protein; Cancer; Cancer cells; Cancer therapies; Cell metabolism; Cells; Dehydrogenases; energy; Fermentation; fluorescent antibody technique; glut1; Glutamic Acid; Glutaminase; Glycolysis; Growth; HeLa Cells; HIF-1α; Humans; Hypoxia-inducible factor 1a; Immunofluorescence; Immunotherapy; Infections; Influence; Ketoglutaric acid; Kinases; L-Lactate dehydrogenase; Laboratories; lactate dehydrogenase; Lactates; Lactic acid; lactic fermentation; Metabolic pathways; Metabolism; mRNA; Myc protein; neoplasm cells; Neoplasms; Oncolysis; oncolytic virus; Orthoreovirus, Avian; Physiological aspects; Plasmids; Proteins; Reagents; Replication; Signal Transduction; structural proteins; Structure; Tricarboxylic acid cycle; Tumor cell lines; Up-Regulation; Viral proteins; Virus Replication; Viruses; Western blotting; Taiwan; United States--US; glut1; c-myc; oncolytic virus; glycolysis; HIF-1α; avian reoviruses; ATeams