Effects of brimonidine tartrate 0.1% ophthalmic solution on the pupil, refraction, and light reflex

• Published in: Scientific Reports Vol. 8; no. 1; pp. 9003 - 5
• Main Authors: Kato, C. O. Sayaka, Shimizu, Kimiya, Kamiya, Kazutaka, Ishikawa, Hitoshi, Igarashi, Akihito
• Format: Journal Article
• Language: English
• Published: London Springer Science and Business Media LLC 13.06.2018; Nature Publishing Group UK; Nature Publishing Group
• Subjects: 59; 692/308/409; 692/699/3161; Acuity; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Agonists - administration & dosage; Adrenergic alpha-2 Receptor Agonists - pharmacology; Adult; Brimonidine Tartrate; Brimonidine Tartrate - administration & dosage; Brimonidine Tartrate - pharmacology; Contraction; Eye; Eye diseases; Female; Glaucoma; Humanities and Social Sciences; Humans; Investigations; Male; multidisciplinary; Ophthalmic Solutions; Ophthalmic Solutions - administration & dosage; Ophthalmic Solutions - pharmacology; Patient satisfaction; Pupil; Pupil - drug effects; Pupil - physiology; Reflex, Pupillary; Reflex, Pupillary - drug effects; Reflex, Pupillary - physiology; Reflexes; Refraction; Refraction, Ocular; Refraction, Ocular - drug effects; Refraction, Ocular - physiology; Science; Science (multidisciplinary); Sympathetic nervous system; Visual Acuity; Visual Acuity - drug effects; Visual Acuity - physiology

This study aimed to assess changes in pupil size, uncorrected visual acuity, refraction, and the direct and consensual light reflexes after instillation of brimonidine 0.1% in healthy subjects. The investigation comprised 46 eyes of 23 healthy subjects with no eye diseases in whom brimonidine 0.1% w...