Aquaporin-4： orthogonal array assembly, CNS functions, and role in neuromyelitis optica - Verkman, Alan S; Ratelade, Julien; Rossi, Andrea; Zhang, Hua; Tradtrantip, Lukmanee (Acta pharmacologica Sinica, 2011)
Keywords: Amino Acid Sequence; Animals; Antibodies, Monoclonal - administration & dosage; Antibodies, Monoclonal - therapeutic use; Aquaporin 4; Aquaporin 4 - chemistry; Aquaporin 4 - immunology; Aquaporin 4 - physiology; Astrocytes; Autoantibodies; Biomedical and Life Sciences; Biomedicine; Brain; Brain injury; Cell migration; Central nervous system; Central Nervous System - immunology; Central Nervous System - metabolism; Central Nervous System - physiology; Demyelinating diseases; Drug Discovery; Edema; Glial fibrillary acidic protein; High-Throughput Screening Assays; Humans; Immunology; Immunoreactivity; Inflammation; Internal Medicine; Kidney; Lung; Medical Microbiology; Molecular Sequence Data; Neuromodulation; Neuromyelitis; Neuromyelitis Optica - drug therapy; Neuromyelitis Optica - immunology; Neuromyelitis Optica - metabolism; Neuronal-glial interactions; Permeability; Pharmacology/Toxicology; Plasma membranes; Protein Binding; Protein Multimerization; Review; Small Molecule Libraries - chemistry; Small Molecule Libraries - therapeutic use; Vaccine; 中枢神经系统; 星形胶质细胞; 正交表; 水通道蛋白4; 神经胶质; 胶质纤维酸性蛋白; 自身免疫性; 视神经; epilepsy; brain edema; transgenic mice; water transport; neuroinflammation; neuromyelitis optica; AQP4; neuroexcitation; astrocyte migration