Hsp90 up-regulates PD-L1 to promote HPV-positive cervical cancer via HER2/PI3K/AKT pathway - Zeng, Jie; He, Si-Li; Li, Li-Jie; Wang, Chen (Molecular medicine (Cambridge, Mass.), 2021)
Keywords: Animals; B7-H1 Antigen - genetics; B7-H1 Antigen - metabolism; Cell Line, Tumor; Cervical cancer; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques - methods; HER2; HPV16; Hsp90; HSP90 Heat-Shock Proteins - genetics; HSP90 Heat-Shock Proteins - metabolism; Human papillomavirus 16 - physiology; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Papillomavirus Infections - genetics; Papillomavirus Infections - metabolism; Papillomavirus Infections - virology; PD-L1; Phosphatidylinositol 3-Kinases - metabolism; Proto-Oncogene Proteins c-akt - metabolism; Receptor, ErbB-2 - genetics; Receptor, ErbB-2 - metabolism; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction - genetics; Transferases - genetics; Transferases - metabolism; Uterine Cervical Neoplasms - genetics; Uterine Cervical Neoplasms - metabolism; Uterine Cervical Neoplasms - virology; Xenograft Model Antitumor Assays - methods; Hsp90; PD-L1; HER2; Cervical cancer; HPV16