Mortality related to drug-resistant organisms in surgical sepsis-3: an 8-year time trend study using sequential organ failure assessment scores

• Published in: European Journal of Clinical Microbiology & Infectious Diseases Vol. 40; no. 3; pp. 535 - 540
• Main Authors: Yoshida, Junichi, Tamura, Tetsuro, Otani, Kazuhiro, Inoue, Masaaki, Miyatake, Eiji, Ishimitsu, Toshiyuki, Nakahara, Chihiro, Tanaka, Masao
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Science and Business Media LLC 01.03.2021; Springer Berlin Heidelberg; Springer Nature B.V
• Subjects: Adult; Aged; Aged, 80 and over; Antiinfectives and antibacterials; Antimicrobial agents; Biomedical and Life Sciences; Biomedicine; Confidence intervals; Diagnosis; Drug resistance; Drug Resistance, Bacterial; Female; Hospital Mortality; Humans; Internal Medicine; Male; Medical Microbiology; Methicillin; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Mortality; Mortality risk; Observational studies; Organ Dysfunction Scores; Original; Original Article; Patients; Prognosis; Public health; Regression analysis; Retrospective Studies; Risk Factors; Sepsis; Staphylococcus aureus; Staphylococcus infections; Statistical analysis; Surgery; Surgery Department, Hospital; Thoracic surgery; β Lactamase; Sequential organ failure assessment score; Methicillin-resistant; Sepsis; Methicillin-resistant Staphylococcus aureus

The difference in sequential organ failure assessment (SOFA) scores from the baseline to sepsis is a known predictor of sepsis-3 outcome, but the prognostic value of drug-resistant organisms for mortality is unexplained. We employed sepsis stewardship and herein report an observational study. Study...