Critical windows of exposure for arsenic-associated impairment of cognitive function in pre-school girls and boys: a population-based cohort study

• Published in: International journal of epidemiology Vol. 40; no. 6; pp. 1593 - 1604
• Main Authors: Hamadani, JD, Tofail, F, Nermell, B, Gardner, R, Shiraji, S, Bottai, M, Arifeen, SE, Huda, SN, Vahter, M
• Format: Journal Article
• Language: English
• Published: Oxford Oxford University Press 01.12.2011
• Subjects: Age; Analysis; Arsenic; Arsenic - toxicity; Arsenic - urine; Arsenic Poisoning - complications; Arsenic Poisoning - epidemiology; Arsenic Poisoning - urine; Bangladesh - epidemiology; Biological and medical sciences; Body Weights and Measures; Boys; Child Development - drug effects; Child Nutrition Disorders - complications; Child Nutrition Disorders - epidemiology; Child, Preschool; Children; Cognition Disorders - chemically induced; Cognition Disorders - urine; Cognitive ability; Drinking water; Environmental Exposure - adverse effects; Environmental Exposure - analysis; Environmental Exposure - statistics & numerical data; Epidemiology; Female; General aspects; Gestation; Girls; Health Surveys; Humans; Infant; Intelligence; Intelligence - drug effects; Intelligence Tests; Longitudinal Studies; Male; Medical sciences; Medicin och hälsovetenskap; Miscellaneous; Pregnancy; Prenatal Exposure Delayed Effects - chemically induced; Prenatal Exposure Delayed Effects - epidemiology; Prenatal Exposure Delayed Effects - urine; Public health. Hygiene; Public health. Hygiene-occupational medicine; Regression analysis; Rural areas; Sex Factors; Side effects; Socioeconomic Factors; Urine; Water; Water Pollutants, Chemical - toxicity; Water Pollutants, Chemical - urine; Water Supply; Bangladesh; Pregnancy; cognitive function; arsenic exposure; maternal urinary arsenic; child urinary arsenic; intelligence quotient; gender differences; Human; Preschool age; Arsenic; Sex; Male; Cognition; Exposure; Epidemiology; Statistical study; Mother; Cohort study; Female; Population; Woman; Child; Public health; Intelligence quotient

Background Exposure to arsenic through drinking water has been associated with impaired cognitive function in school-aged children in a few cross-sectional studies; however, there is little information on critical windows of exposure. Methods We conducted a population-based longitudinal study in rur...