Emerging role of transforming growth factor-β-regulated long non-coding RNAs in prostate cancer pathogenesis

• Published in: Cancer pathogenesis and therapy Vol. 1; no. 3; pp. 195 - 204
• Main Authors: Shree, Bakhya, Das, Koyel, Sharma, Vivek
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.07.2023; Elsevier
• Subjects: Androgen deprivation therapy; Androgen-independent prostate cancer; Benign prostatic hyperplasia; Castration-resistant prostate cancer; LncRNA; Prostate cancer; Prostate-specific antigen; Review; TGF-β; Castration-resistant prostate cancer; Androgen deprivation therapy; Prostate-specific antigen; LncRNA; TGF-β; Benign prostatic hyperplasia; Androgen-independent prostate cancer; Prostate cancer
• ISSN: 2949-7132; 2097-2563; 2949-7132
• DOI: 10.1016/j.cpt.2022.12.003

Prostate cancer (PCa) is the most common malignancy in men. Despite aggressive therapy involving surgery and hormonal treatments, the recurrence and emergence of metastatic castration-resistant prostate cancer (CRPCa) remain a major challenge. Dysregulation of the transforming growth factor-β (TGF-β...