Polycystic ovary syndrome (PCOS) and kisspeptin - A Sri Lankan study

• Published in: Journal of postgraduate medicine Vol. 65; no. 1; pp. 18 - 23
• Main Authors: Umayal, B, Jayakody, S, Chandrasekharan, N, Wijesundera, W, Wijeyaratne, C
• Format: Journal Article
• Language: English
• Published: India Wolters Kluwer India Pvt. Ltd 01.01.2019; Medknow Publications and Media Pvt. Ltd; Medknow Publications & Media Pvt. Ltd; Medknow Publications & Media Pvt Ltd
• Subjects: Adolescent; Adult; Age; Amenorrhea; Androgens; Anthropometry; Body Mass Index; Brain; Case-Control Studies; Child development; Development and progression; Diagnosis; Female; Genes; Gonadotropin-Releasing Hormone - genetics; Gonadotropins; Gynecology; Health aspects; Hormones; Humans; Hypothalamic hormones; Kisspeptins - blood; Menstruation; Metabolism; Neurons; Obstetrics; Original; Peptides; Physiological aspects; Pituitary hormones; Polycystic ovary syndrome; Polycystic Ovary Syndrome - blood; Polycystic Ovary Syndrome - ethnology; Polycystic Ovary Syndrome - genetics; Polymorphism; Population; Puberty; Receptors, Kisspeptin-1 - genetics; Sri Lanka - epidemiology; Studies; Ultrasonic imaging; Women; Young Adult; Young women; Sri Lanka; KISS1; Adolescence; GPR54; kisspeptin; polycystic ovary syndrome
• ISSN: 0022-3859; 0972-2823
• DOI: 10.4103/jpgm.JPGM_683_17

Context: Polycystic ovary syndrome (PCOS) is the commonest endocrine disorder affecting young women. Kisspeptins are a family of closely related peptides encoded by Kiss1 gene that controls the hypothalamic-pituitary-gonadal axis by binding to its receptor (GPR54) expressed in gonadotropin-releasing...