Analysis of global human gut metagenomes shows that metabolic resilience potential for short-chain fatty acid production is strongly influenced by lifestyle

• Published in: Scientific reports Vol. 11; no. 1; pp. 1724 - 11
• Main Authors: Jacobson, David K., Honap, Tanvi P., Ozga, Andrew T., Meda, Nicolas, Kagoné, Thérèse S., Carabin, Hélène, Spicer, Paul, Tito, Raul Y., Obregon-Tito, Alexandra J., Reyes, Luis Marin, Troncoso-Corzo, Luzmila, Guija-Poma, Emilio, Sankaranarayanan, Krithivasan, Lewis, Cecil M.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 18.01.2021; Nature Publishing Group; Nature Portfolio
• Subjects: 631/158/855; 631/208/325; 631/326/2565; Acid production; Bacteria - classification; Bacteria - genetics; Computational Biology - methods; Developed Countries; Ecological adaptation; Fatty acids; Fatty Acids, Volatile - analysis; Feces - microbiology; Gastrointestinal Microbiome - genetics; Humanities and Social Sciences; Humans; Intestinal microflora; Life Style; Metabolism; Metagenome; Metagenomics; Microbiomes; multidisciplinary; Phylogenetics; Phylogeny; Science; Science (multidisciplinary); Species; Species diversity; Taxonomy

High taxonomic diversity in non-industrial human gut microbiomes is often interpreted as beneficial; however, it is unclear if taxonomic diversity engenders ecological resilience (i.e. community stability and metabolic continuity). We estimate resilience through genus and species-level richness, phy...