Influence of age and nutritional status on the performance of the tuberculin skin test and QuantiFERON-TB gold in-tube in young children evaluated for tuberculosis in Southern India

• Published in: The Pediatric infectious disease journal Vol. 33; no. 10; p. e260
• Main Authors: Jenum, Synne, Selvam, Sumithra, Mahelai, Diana, Jesuraj, Nelson, Cárdenas, Vicky, Kenneth, John, Hesseling, Anneke C, Doherty, Timothy Mark, Vaz, Mario, Grewal, Harleen M S
• Format: Journal Article
• Language: English
• Published: United States 01.10.2014
• Subjects: Age Factors; Child, Preschool; Female; Humans; India; Infant; Interferon-gamma Release Tests - methods; Male; Mycobacterium tuberculosis - immunology; Nutritional Status; Prospective Studies; Sensitivity and Specificity; Skin Tests - methods; Tuberculin Test - methods; Tuberculosis - diagnosis; India

Reliable identification of Mycobacterium tuberculosis infection or tuberculosis (TB) disease in young children is vital to assure adequate preventive and curative treatment. The tuberculin skin test (TST) and IFNγ-release assays may supplement the diagnosis of pediatric TB as cases are typically bac...