Accumulation of amyloid-β by astrocytes result in enlarged endosomes and microvesicle-induced apoptosis of neurons - Söllvander, Sofia; Nikitidou, Elisabeth; Brolin, Robin; Söderberg, Linda; Sehlin, Dag; Lannfelt, Lars; Erlandsson, Anna (Molecular neurodegeneration, 2016)
Keywords: Alzheimer Disease - metabolism; Alzheimer Disease - pathology; Alzheimer's Disease; Amyloid beta-Peptides - metabolism; Amyloid beta-protein; Analysis; Animals; Apoptosis; Apoptosis - physiology; Astrocytes - metabolism; Astrocytes - pathology; Blotting, Western; Care and treatment; Cell-Derived Microparticles - metabolism; Cells, Cultured; Coculture Techniques; Complications and side effects; Degradation; Development and progression; Endosomes - metabolism; Enlarged vacuole; Enzyme-Linked Immunosorbent Assay; Glia; Immunohistochemistry; Influence; Medical Science; Medicinsk vetenskap; Mice; Mice, Inbred C57BL; Microscopy, Electron, Transmission; Microvesicle; Neurons - metabolism; Neurons - pathology; Phagocytosis; protofibril; Protofibrils; Time-Lapse Imaging; Degradation; Alzheimer’s disease; Enlarged vacuole; Glia; Microvesicle; Phagocytosis; Protofibrils