Preclinical and clinical development of a dengue recombinant subunit vaccine - Manoff, Susan B.; George, Sarah L.; Bett, Andrew J.; Yelmene, Michele L.; Dhanasekaran, Govindarajan; Eggemeyer, Linda; Sausser, Michele L.; Dubey, Sheri A.; Casimiro, Danilo R.; Clements, David E.; Martyak, Timothy; Pai, Vidya; et al. (Vaccine, 2015)
Keywords: adjuvants; Adjuvants, Immunologic - administration & dosage; adults; Allergy and Immunology; Aluminum; Aluminum Hydroxide - administration & dosage; Animals; Antibodies, Neutralizing - blood; Antibodies, Viral - blood; Antigens; Cholesterol - administration & dosage; Clinical trials; Clinical Trials, Phase I as Topic; dengue; Dengue - epidemiology; Dengue - prevention & control; Dengue fever; Dengue vaccine; Dengue Vaccines - administration & dosage; Dengue Vaccines - genetics; Dengue Vaccines - immunology; Dengue Vaccines - isolation & purification; Dengue virus; Deoxyribonucleic acid; Disease; DNA; Drosophila; Drug Combinations; Drug Evaluation, Preclinical; durability; Flaviviridae; glycoproteins; Hawaii; Humans; Immunization Schedule; Infections; interferon-gamma; Interferon-gamma - secretion; Macaca; Monkeys & apes; Mortality; neutralization; neutralizing antibodies; Phospholipids - administration & dosage; Proteins; Recombinant; Saponins - administration & dosage; Studies; Subunit; subunit vaccines; T-lymphocytes; T-Lymphocytes - immunology; Vaccines; Vaccines, Subunit - administration & dosage; Vaccines, Subunit - genetics; Vaccines, Subunit - immunology; Vaccines, Subunit - isolation & purification; Vaccines, Synthetic - administration & dosage; Vaccines, Synthetic - genetics; Vaccines, Synthetic - immunology; Vaccines, Synthetic - isolation & purification; Vector-borne diseases; viral load; Viruses; ISE, USA, Hawaii; Hawaii; Subunit; Dengue vaccine; Recombinant