Molecular determinants and mechanism for antibody cocktail preventing SARS-CoV-2 escape - Ku, Zhiqiang; Xie, Xuping; Davidson, Edgar; Ye, Xiaohua; Su, Hang; Menachery, Vineet D.; Li, Yize; Yuan, Zihao; Zhang, Xianwen; Muruato, Antonio E.; i Escuer, Ariadna Grinyo; Tyrell, Breanna; et al. (Nature communications, 2021)
Keywords: 631/250/2152/2153/1291; 631/326/596/4130; 64/60; 82/1; 82/80; ACE2; Angiotensin-converting enzyme 2; Angiotensin-Converting Enzyme 2 - metabolism; Animals; Antibodies; Antibodies, Monoclonal - chemistry; Antibodies, Monoclonal - immunology; Antibodies, Monoclonal - pharmacology; Antibodies, Neutralizing - immunology; Antibodies, Viral - genetics; Antibodies, Viral - immunology; Binding; Chlorocebus aethiops; COVID-19; COVID-19 - drug therapy; COVID-19 - virology; Determinants; Disease Models, Animal; Epitopes; Female; Humanities and Social Sciences; Humans; Immunoglobulin Fragments - genetics; Immunoglobulin Fragments - immunology; Immunoglobulin G - genetics; Immunoglobulin G - immunology; Mice; Mice, Inbred BALB C; Models, Molecular; multidisciplinary; Mutation; Neutralizing; Phages; Protein Binding; Protein folding; Receptors; SARS-CoV-2 - drug effects; SARS-CoV-2 - genetics; SARS-CoV-2 - immunology; Science; Science (multidisciplinary); Severe acute respiratory syndrome coronavirus 2; Spike Glycoprotein, Coronavirus - genetics; Spike Glycoprotein, Coronavirus - immunology; Vero Cells