Elevated IgE and atopy in patients treated for early-onset ADA-SCID

Because nonatopic patients were much younger in our cohort, it is quite likely that many of them will go on to develop allergic disease as well.

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Published inJournal of allergy and clinical immunology Vol. 132; no. 6; pp. 1444 - 1446.e5
Main Authors Lawrence, Monica G., MD, Barber, John S., BA, Sokolic, Robert A., MD, Garabedian, Elizabeth K., RN, MSLS, Desai, Avanti N., MS, O'Brien, Michelle, RN, BSN, Jones, Nina, RN, BSN, Bali, Pawan, PhD, Hershfield, Michael S., MD, Stone, Kelly D., MD, PhD, Candotti, Fabio, MD, Milner, Joshua D., MD
Format Journal Article
LanguageEnglish
Published New York, NY Mosby, Inc 01.12.2013
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Abstract Because nonatopic patients were much younger in our cohort, it is quite likely that many of them will go on to develop allergic disease as well.
AbstractList Because nonatopic patients were much younger in our cohort, it is quite likely that many of them will go on to develop allergic disease as well.
Author Jones, Nina, RN, BSN
Hershfield, Michael S., MD
Desai, Avanti N., MS
Bali, Pawan, PhD
Sokolic, Robert A., MD
Barber, John S., BA
Lawrence, Monica G., MD
Garabedian, Elizabeth K., RN, MSLS
O'Brien, Michelle, RN, BSN
Stone, Kelly D., MD, PhD
Milner, Joshua D., MD
Candotti, Fabio, MD
AuthorAffiliation 2 Genetics and Molecular Biology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892
1 Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892
4 Department of Medicine, Duke University Medical Center, Durham, NC 27705
3 Clinical Research Directorate/CMRP, SAIC-Frederick, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702
AuthorAffiliation_xml – name: 2 Genetics and Molecular Biology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892
– name: 4 Department of Medicine, Duke University Medical Center, Durham, NC 27705
– name: 3 Clinical Research Directorate/CMRP, SAIC-Frederick, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702
– name: 1 Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892
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10.1016/S0165-2478(98)00083-2
10.1182/blood-2007-05-092429
10.1111/imr.12032
10.1016/j.jaci.2010.10.008
10.1172/JCI200110360
10.1182/blood-2009-06-189209
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10.1016/j.clim.2011.05.007
10.1016/j.jaci.2010.11.033
10.1016/j.jaci.2007.09.029
10.1542/peds.2009-3171
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Issue 6
Keywords Human
Allergy
Immunopathology
IgE
Metabolic diseases
Adenosine deaminase deficiency
Enzymopathy
Genetic disease
Atopy
Immunology
Treatment
Age of onset
Early
Purine
Language English
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Authors contributed equally to this work
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Snippet Because nonatopic patients were much younger in our cohort, it is quite likely that many of them will go on to develop allergic disease as well.
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SubjectTerms Adenosine Deaminase - genetics
Adolescent
Adult
Allergies
Allergy and Immunology
Biological and medical sciences
Bone marrow
Bone Marrow Transplantation
Cells, Cultured
Child
Child, Preschool
Cohort Studies
Cross-Sectional Studies
Cytokines - metabolism
Dermatitis
Drug therapy
Enzyme Replacement Therapy
Female
Food allergies
Fundamental and applied biological sciences. Psychology
Fundamental immunology
Gene therapy
Genetic Therapy
Humans
Immune system
Immunoglobulin E - genetics
Immunoglobulin E - metabolism
Immunologic Memory
Infant
Male
Medical sciences
Mutation - genetics
Nose
Phenotype
Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis
Severe Combined Immunodeficiency - genetics
Severe Combined Immunodeficiency - immunology
Severe Combined Immunodeficiency - therapy
Th2 Cells - immunology
Young Adult
Title Elevated IgE and atopy in patients treated for early-onset ADA-SCID
URI https://www.clinicalkey.es/playcontent/1-s2.0-S0091674913009731
https://dx.doi.org/10.1016/j.jaci.2013.05.040
https://www.ncbi.nlm.nih.gov/pubmed/23895897
https://www.proquest.com/docview/1545854314
https://www.proquest.com/docview/1462762868
https://pubmed.ncbi.nlm.nih.gov/PMC3844080
Volume 132
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