Spatial heterogeneity of hepatic fibrosis in primary sclerosing cholangitis vs. viral hepatitis assessed by MR elastography

• Published in: Scientific reports Vol. 11; no. 1; pp. 9820 - 8
• Main Authors: Reiter, Rolf, Shahryari, Mehrgan, Tzschätzsch, Heiko, Klatt, Dieter, Siegmund, Britta, Hamm, Bernd, Braun, Jürgen, Sack, Ingolf, Asbach, Patrick
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 10.05.2021; Nature Publishing Group; Nature Portfolio
• Subjects: 692/308/53; 692/4020/4021/1328/1325/2744; 692/4020/4021/1607/1604; 692/4020/4021/1607/1605; 692/4020/4021/1607/234; 692/4020/4021/1607/2744; 692/53; 692/699/1503/234/2513; Cholangitis; Coefficient of variation; Correctional personnel; Fibrosis; Hepatitis; Heterogeneity; Humanities and Social Sciences; Liver; Magnetic resonance imaging; multidisciplinary; Science; Science (multidisciplinary); Spatial heterogeneity

Spatial heterogeneity of hepatic fibrosis in primary sclerosing cholangitis (PSC) in comparison to viral hepatitis was assessed as a potential new biomarker using MR elastography (MRE). In this proof-of-concept study, we hypothesized a rather increased heterogeneity in PSC and a rather homogeneous d...