Specificity models in MAPK cascade signaling

• Published in: FEBS open bio Vol. 13; no. 7; pp. 1177 - 1192
• Main Authors: Ma, Yan, Nicolet, Jade
• Format: Journal Article
• Language: English
• Published: England John Wiley & Sons, Inc 01.07.2023; John Wiley and Sons Inc; Wiley
• Subjects: Animals; Flowers & plants; Intermediates; Kinases; Ligands; MAP kinase; MAP Kinase Signaling System - physiology; MAPK cascade; MAPK Signalling; mitogen-activated protein kinase; Mitogen-Activated Protein Kinases - metabolism; Phosphorylation; plant signaling; Proteins; Review; Reviews; RLK receptors; Saccharomyces cerevisiae - metabolism; Signal Transduction; signaling specificity; yeasts; signaling specificity; MAPK cascade; RLK receptors; plant signaling

The precise execution of various cellular functions relies on the maintenance of signaling specificity from input detection to cellular outputs. However, diverse signaling pathways share similar or identical intermediate components. A well‐conserved intermediate, the Mitogen‐Activated Protein Kinase...