The protective effect of sinapic acid in osteoarthritis: In vitro and in vivo studies - Li, Xiaobin; Lin, Jian; Ding, Xiaoxia; Xuan, Jiangwei; Hu, Zhichao; Wu, Dengying; Zhu, Xingyu; Feng, Zhenhua; Ni, Wenfei; Wu, Aimin (Journal of cellular and molecular medicine, 2019)
Keywords: ADAM protein; Aggrecan; Animal models; Animals; Arthritis; Cells, Cultured; Chondrocytes; Chondrocytes - drug effects; Chondrocytes - metabolism; Coumaric Acids - pharmacology; Cyclooxygenase 2 - metabolism; Dinoprostone - metabolism; Female; Heme; Heme Oxygenase-1 - metabolism; Humans; IL‐1β; Inflammation; Interleukin-1beta - metabolism; Interleukin-6 - metabolism; Male; Matrix metalloproteinase; Matrix Metalloproteinase 13 - metabolism; Mice; Mice, Inbred C57BL; Middle Aged; NF-kappa B - metabolism; NF‐κB; Nitric oxide; Nitric Oxide - metabolism; Nitric Oxide Synthase Type II - metabolism; Nitric-oxide synthase; Nrf2; Original; Osteoarthritis; Osteoarthritis - drug therapy; Osteoarthritis - metabolism; Oxygenase; Prostaglandin E2; Prostaglandin endoperoxide synthase; Protective Agents - pharmacology; Sinapic acid; Thrombospondin; Tumor necrosis factor; Tumor Necrosis Factor-alpha - metabolism; Tumor necrosis factor-TNF; Tumors; NF-κB; chondrocytes; IL-1β; Nrf2; inflammation; sinapic acid