Exercise Training Modulates Gut Microbiota Profile and Improves Endotoxemia

• Published in: Medicine and science in sports and exercise Vol. 52; no. 1; p. 94
• Main Authors: Motiani, Kumail K, Collado, M Carmen, Eskelinen, Jari-Joonas, Virtanen, Kirsi A, LÖyttyniemi, Eliisa, Salminen, Seppo, Nuutila, Pirjo, Kalliokoski, Kari K, Hannukainen, Jarna C
• Format: Journal Article
• Language: English
• Published: United States 01.01.2020
• Subjects: Acute-Phase Proteins - metabolism; Biomarkers - metabolism; Body Mass Index; Carrier Proteins - metabolism; Diabetes Mellitus, Type 2 - metabolism; Endotoxemia - metabolism; Endotoxemia - prevention & control; Female; Gastrointestinal Microbiome; Humans; Inflammation - metabolism; Insulin Resistance - physiology; Intestinal Mucosa - metabolism; Male; Membrane Glycoproteins - metabolism; Middle Aged; Obesity - metabolism; Oxygen Consumption - physiology; Physical Conditioning, Human - methods; Prediabetic State - metabolism; Tumor Necrosis Factor-alpha - metabolism

Intestinal metabolism and microbiota profiles are impaired in obesity and insulin resistance. Moreover, dysbiotic gut microbiota has been suggested to promote systemic low-grade inflammation and insulin resistance through the release of endotoxins particularly lipopolysaccharides. We have previously...