Impact of H3.3 K27M Mutation on Prognosis and Survival of Grade IV Spinal Cord Glioma on the Basis of New 2016 World Health Organization Classification of the Central Nervous System

• Published in: Neurosurgery Vol. 84; no. 5; pp. 1072 - 1081
• Main Authors: Yi, Seong, Choi, Sunkyu, Shin, Dong Ah, Kim, Du Su, Choi, Junjeong, Ha, Yoon, Kim, Keung Nyun, Suh, Chang-Ok, Chang, Jong Hee, Kim, Se Hoon, Yoon, Do Heum
• Format: Journal Article
• Language: English
• Published: United States Oxford University Press 01.05.2019; Copyright by the Congress of Neurological Surgeons; Wolters Kluwer Health, Inc
• Subjects: Adult; Central nervous system; Classification; Disease-Free Survival; Diseases; Female; Genetic aspects; Glioblastomas; Glioma; Glioma - classification; Glioma - genetics; Glioma - mortality; Gliomas; Health; Histones - genetics; Humans; Male; Medical prognosis; Medical supplies; Middle Aged; Mutation; Nervous system; Neurosurgery; Prognosis; Public health; Spinal cord; Spinal Cord Neoplasms - classification; Spinal Cord Neoplasms - genetics; Spinal Cord Neoplasms - mortality; Surgery; Survival Analysis; Therapeutics; Tumors; World Health Organization; South Korea; Survival analysis; Spinal cord; Prognosis; Glioma; Grade IV; WHO classification; H3 K27M

Abstract BACKGROUND Spinal cord glioma grade IV is a rare, diffuse midline glioma. H3 K27M-mutant was classified in a different entity in the 2016 World Health Organization (WHO) classification recently. No reports about prognosis of spinal cord glioma grade IV are available yet. OBJECTIVE To analyz...