A mutual information-based in vivo monitoring of adaptive response to targeted therapies in melanoma - Bugi-Marteyn, Aurore; Noulet, Fanny; Liaudet, Nicolas; Merat, Rastine (Neoplasia (New York, N.Y.), 2021)
Keywords: Adaptive resistance; Algorithms; Animals; Biomarkers, Tumor; BRAF inhibitor; Disease Management; Disease Models, Animal; Disease Susceptibility; Drug Resistance, Neoplasm; ELAVL1/HuR; Gene Expression Regulation, Neoplastic - drug effects; Humans; Immunohistochemistry; Information theory; Melanoma; Melanoma - diagnosis; Melanoma - drug therapy; Melanoma - etiology; Melanoma - metabolism; Mice; Models, Theoretical; Molecular Targeted Therapy - adverse effects; Molecular Targeted Therapy - methods; Mutual information; Original Research; Protein Kinase Inhibitors - pharmacology; Protein Kinase Inhibitors - therapeutic use; Single-Cell Analysis - methods; Treatment Outcome; Xenograft Model Antitumor Assays; Adaptive resistance; BRAF inhibitor; ELAVL1/HuR; Mutual information; Melanoma; Information theory