Immune response to SARS-CoV-2 in health care workers following a COVID-19 outbreak: A prospective longitudinal study

• Published in: Journal of clinical virology Vol. 130; p. 104575
• Main Authors: Fill Malfertheiner, Sara, Brandstetter, Susanne, Roth, Samra, Harner, Susanne, Buntrock-Döpke, Heike, Toncheva, Antoaneta A., Borchers, Natascha, Gruber, Rudolf, Ambrosch, Andreas, Kabesch, Michael, Häusler, Sebastian
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.09.2020
• Subjects: Adolescent; Adult; Aged; Antibodies, Viral - blood; Betacoronavirus; Corona virus; Coronavirus Infections - diagnosis; Coronavirus Infections - immunology; COVID-19; Cross-Sectional Studies; Female; Germany; Health care workers; Health Personnel - statistics & numerical data; Humans; Immune response; Immunoglobulin G - blood; Longitudinal Studies; Male; Middle Aged; Pandemics; Pneumonia, Viral - diagnosis; Pneumonia, Viral - immunology; Prospective Studies; SARS-CoV-2; SARS-CoV-2 antibodies; Seroconversion; Young Adult; Germany; COVID-19; Corona virus; Health care workers; SARS-CoV-2; Immune response; SARS-CoV-2 antibodies

Currently, little is known about the progression of an immune response against SARSCoV- 2 upon infection or sub-infection-exposure over time. We examined the serologic response in healthcare workers up to 12 weeks after a well-documented and contained outbreak and compared results with findings from...