Administration of a dietary supplement (N-oleyl-phosphatidylethanolamine and epigallocatechin-3-gallate formula) enhances compliance with diet in healthy overweight subjects: a randomized controlled trial

• Published in: British journal of nutrition Vol. 101; no. 3; pp. 457 - 464
• Main Authors: Rondanelli, Mariangela, Opizzi, Annalisa, Solerte, Sebastiano Bruno, Trotti, Rosita, Klersy, Catherine, Cazzola, Roberta
• Format: Journal Article
• Language: English
• Published: Cambridge, UK Cambridge University Press 01.02.2009
• Subjects: administration & dosage; Adolescent; Adult; analogs & derivatives; analysis; Appetite; Appetite Depressants; Appetite Depressants - administration & dosage; binging; Biological and medical sciences; Biomarkers; Biomarkers - blood; blood; Blood Glucose; Blood Glucose - analysis; Body Composition; Catechin; Catechin - administration & dosage; Catechin - analogs & derivatives; Depression; Diet; diet therapy; Diet, Reducing; Dietary adherence; Dietary Supplements; Double-Blind Method; Eating; Eating behavior; epigallocatechin; Epigallocatechin-3-gallate; ethanolamine; Feeding. Feeding behavior; Female; Females; food intake; Fundamental and applied biological sciences. Psychology; human nutrition; Humans; Insulin; Insulin - blood; Insulin resistance; low calorie diet; Male; Males; men; metabolism; Metabolites; Middle Aged; N-oleyl-phosphatidylethanolamine; Nutrition; nutritional intervention; Obesity; overweight; Overweight - blood; Overweight - diet therapy; Patient Compliance; Phosphatidylethanolamines; Phosphatidylethanolamines - administration & dosage; randomized clinical trials; Satiation; Statistics, Nonparametric; Vertebrates: anatomy and physiology, studies on body, several organs or systems; Weight control; Weight Loss; women; Appetite; Insulin resistance; N-oleyl-phosphatidylethanolamine; Dietary adherence; Epigallocatechin-3-gallate; Endocrinopathy; Phosphatidylethanolamine; Healthy subject; Compliance; Metabolic diseases; Adhesion; Feeding; Overweight; Dietary adherence: Insulin resistance: Appetite: N-oleyl-phosphatidylethanolamine: Epigallocatechin-3-gallate; Target tissue resistance; Vertebrata; Mammalia; Diet

Many studies have found that N-oleyl-ethanolamine (NOE), a metabolite of N-oleyl-phosphatidylethanolamine (NOPE), and epigallocatechin-3-gallate (EGCG) inhibit food intake. The main aim of this study was to evaluate the efficacy of 2 months of administration of an oily NOPE–EGCG complex (85 mg NOPE...