Bridging the Gap: Pregnancy—And Lactation—Associated Osteoporosis

Early diagnosis of pregnancy- and lactation-associated osteoporosis (PLO) is mandatory for a good outcome. Standard care is not a matter of conventional guidelines, rather it requires an individualized strategy while true overall incidence and pathogeny remain open issues. This is a narrative review...

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Published in	Diagnostics (Basel) Vol. 13; no. 9; p. 1615
Main Authors	Carsote, Mara, Turturea, Maria Roxana, Valea, Ana, Buescu, Cristian, Nistor, Claudiu, Turturea, Ionut Florin
Format	Journal Article
Language	English
Published	Switzerland MDPI AG 03.05.2023 MDPI
Subjects	Antipsychotic drugs Bone surgery Breastfeeding & lactation calcium Case reports Chronic illnesses Corticosteroids Denosumab fracture Fractures hip lactation Magnetic resonance imaging Metabolism Orthopedics Osteoporosis Physiology Pregnancy Pregnant women Review Surveys Vitamin D Vitamin deficiency romosozumab calcium teripartide lactation pregnancy vertebral bisphosphonates osteoporosis hip fracture
Online Access	Get full text
ISSN	2075-4418 2075-4418
DOI	10.3390/diagnostics13091615

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Abstract	Early diagnosis of pregnancy- and lactation-associated osteoporosis (PLO) is mandatory for a good outcome. Standard care is not a matter of conventional guidelines, rather it requires an individualized strategy while true overall incidence and pathogeny remain open issues. This is a narrative review based on full-length English articles, published between January 2021 and March 2023 and accessed via PubMed (no traumatic fractures or secondary osteoporosis are included). Our case-sample-based analysis included 836 females with PLO (the largest cohort based on published cases so far) through 12 studies and 24 single case reports. Except for one survey, these involved retrospective cohorts of small size (6–10 females/study) to medium size (23–47 women/study), and large cohorts with >50 subjects per study (a maximum of 379). Age of diagnosis: from 24 to 40 years for case reports (most subjects being over 30 and primigravida), while original studies indicated an average age between 31 and 34.18 years. Type of fractures underlined a most frequent vertebral phenotype (a mean of 2 to 5.8 vertebral fractures per patient) versus a most severe non-vertebral phenotype (hip and femoral neck fractures mostly requiring surgery). Potential contributors varied: smoking (1/3–1/2 of subjects), family history of osteoporosis (1/3), heparin and glucocorticoid use in pregnancy, low body mass index (majority of cases), hypovitaminosis D; and (with a low level of statistical significance) anti-psychotic medication, gestational diabetes, lupus, thrombophilia, anemia, in vitro fertilization (1/3 in one study), twin pregnancy, tocolysis with MgSO4, and postpartum thyroiditis. Most remarkably, up to 50% of PLO patients harbor mutations of LRP5, WNT1, and COL1A1/A2 (more damaged form with potential benefits from osteoanabolic drugs); gene testing might become the new norm in PLO. The low index of clinical suspicion should be supported by performing magnetic resonance imaging (gold standard in pregnancy) with DXA (in lactation). Low bone mineral density is expected (Z-score varying from −2.2 SD to −4 SD, unless normal which does not exclude PLO). Bone turnover markers might be useful in individuals with normal DXA, in pregnancy when DXA cannot be performed, and in following the response to anti-osteoporosis drugs. Alternatively, microarchitecture damage might be reflected by DXA-trabecular bone score and high-resolution peripheral quantitative computed tomography. Specific medical interventions are currently focused on teriparatide (TPT) use (3 studies; n = 99 females treated with TPT and an additional subgroup of 18 patients from the gene-analysis-based study, thus a total of 117 females) which seems to be the therapy of choice as reflected by these new data: 6–24 months, 20 µg/day, no sequential therapy needed; case selection based on high fracture risk is necessary). The first case using romosozumab was reported in 2022. PAO/LAO remains a challenging condition which is a battle for the wellbeing of two individuals, on one hand, considering maternal-fetal outcomes and taking care of the offspring, but it is a battle for a multidisciplinary team, on the other hand, since a standardized approach is lacking.
AbstractList	Early diagnosis of pregnancy- and lactation-associated osteoporosis (PLO) is mandatory for a good outcome. Standard care is not a matter of conventional guidelines, rather it requires an individualized strategy while true overall incidence and pathogeny remain open issues. This is a narrative review based on full-length English articles, published between January 2021 and March 2023 and accessed via PubMed (no traumatic fractures or secondary osteoporosis are included). Our case-sample-based analysis included 836 females with PLO (the largest cohort based on published cases so far) through 12 studies and 24 single case reports. Except for one survey, these involved retrospective cohorts of small size (6–10 females/study) to medium size (23–47 women/study), and large cohorts with >50 subjects per study (a maximum of 379). Age of diagnosis: from 24 to 40 years for case reports (most subjects being over 30 and primigravida), while original studies indicated an average age between 31 and 34.18 years. Type of fractures underlined a most frequent vertebral phenotype (a mean of 2 to 5.8 vertebral fractures per patient) versus a most severe non-vertebral phenotype (hip and femoral neck fractures mostly requiring surgery). Potential contributors varied: smoking (1/3–1/2 of subjects), family history of osteoporosis (1/3), heparin and glucocorticoid use in pregnancy, low body mass index (majority of cases), hypovitaminosis D; and (with a low level of statistical significance) anti-psychotic medication, gestational diabetes, lupus, thrombophilia, anemia, in vitro fertilization (1/3 in one study), twin pregnancy, tocolysis with MgSO4, and postpartum thyroiditis. Most remarkably, up to 50% of PLO patients harbor mutations of LRP5, WNT1, and COL1A1/A2 (more damaged form with potential benefits from osteoanabolic drugs); gene testing might become the new norm in PLO. The low index of clinical suspicion should be supported by performing magnetic resonance imaging (gold standard in pregnancy) with DXA (in lactation). Low bone mineral density is expected (Z-score varying from −2.2 SD to −4 SD, unless normal which does not exclude PLO). Bone turnover markers might be useful in individuals with normal DXA, in pregnancy when DXA cannot be performed, and in following the response to anti-osteoporosis drugs. Alternatively, microarchitecture damage might be reflected by DXA-trabecular bone score and high-resolution peripheral quantitative computed tomography. Specific medical interventions are currently focused on teriparatide (TPT) use (3 studies; n = 99 females treated with TPT and an additional subgroup of 18 patients from the gene-analysis-based study, thus a total of 117 females) which seems to be the therapy of choice as reflected by these new data: 6–24 months, 20 µg/day, no sequential therapy needed; case selection based on high fracture risk is necessary). The first case using romosozumab was reported in 2022. PAO/LAO remains a challenging condition which is a battle for the wellbeing of two individuals, on one hand, considering maternal-fetal outcomes and taking care of the offspring, but it is a battle for a multidisciplinary team, on the other hand, since a standardized approach is lacking. Early diagnosis of pregnancy- and lactation-associated osteoporosis (PLO) is mandatory for a good outcome. Standard care is not a matter of conventional guidelines, rather it requires an individualized strategy while true overall incidence and pathogeny remain open issues. This is a narrative review based on full-length English articles, published between January 2021 and March 2023 and accessed via PubMed (no traumatic fractures or secondary osteoporosis are included). Our case-sample-based analysis included 836 females with PLO (the largest cohort based on published cases so far) through 12 studies and 24 single case reports. Except for one survey, these involved retrospective cohorts of small size (6-10 females/study) to medium size (23-47 women/study), and large cohorts with >50 subjects per study (a maximum of 379). Age of diagnosis: from 24 to 40 years for case reports (most subjects being over 30 and primigravida), while original studies indicated an average age between 31 and 34.18 years. Type of fractures underlined a most frequent vertebral phenotype (a mean of 2 to 5.8 vertebral fractures per patient) versus a most severe non-vertebral phenotype (hip and femoral neck fractures mostly requiring surgery). Potential contributors varied: smoking (1/3-1/2 of subjects), family history of osteoporosis (1/3), heparin and glucocorticoid use in pregnancy, low body mass index (majority of cases), hypovitaminosis D; and (with a low level of statistical significance) anti-psychotic medication, gestational diabetes, lupus, thrombophilia, anemia, in vitro fertilization (1/3 in one study), twin pregnancy, tocolysis with MgSO4, and postpartum thyroiditis. Most remarkably, up to 50% of PLO patients harbor mutations of , and (more damaged form with potential benefits from osteoanabolic drugs); gene testing might become the new norm in PLO. The low index of clinical suspicion should be supported by performing magnetic resonance imaging (gold standard in pregnancy) with DXA (in lactation). Low bone mineral density is expected (Z-score varying from -2.2 SD to -4 SD, unless normal which does not exclude PLO). Bone turnover markers might be useful in individuals with normal DXA, in pregnancy when DXA cannot be performed, and in following the response to anti-osteoporosis drugs. Alternatively, microarchitecture damage might be reflected by DXA-trabecular bone score and high-resolution peripheral quantitative computed tomography. Specific medical interventions are currently focused on teriparatide (TPT) use (3 studies; = 99 females treated with TPT and an additional subgroup of 18 patients from the gene-analysis-based study, thus a total of 117 females) which seems to be the therapy of choice as reflected by these new data: 6-24 months, 20 µg/day, no sequential therapy needed; case selection based on high fracture risk is necessary). The first case using romosozumab was reported in 2022. PAO/LAO remains a challenging condition which is a battle for the wellbeing of two individuals, on one hand, considering maternal-fetal outcomes and taking care of the offspring, but it is a battle for a multidisciplinary team, on the other hand, since a standardized approach is lacking. Early diagnosis of pregnancy- and lactation-associated osteoporosis (PLO) is mandatory for a good outcome. Standard care is not a matter of conventional guidelines, rather it requires an individualized strategy while true overall incidence and pathogeny remain open issues. This is a narrative review based on full-length English articles, published between January 2021 and March 2023 and accessed via PubMed (no traumatic fractures or secondary osteoporosis are included). Our case-sample-based analysis included 836 females with PLO (the largest cohort based on published cases so far) through 12 studies and 24 single case reports. Except for one survey, these involved retrospective cohorts of small size (6–10 females/study) to medium size (23–47 women/study), and large cohorts with >50 subjects per study (a maximum of 379). Age of diagnosis: from 24 to 40 years for case reports (most subjects being over 30 and primigravida), while original studies indicated an average age between 31 and 34.18 years. Type of fractures underlined a most frequent vertebral phenotype (a mean of 2 to 5.8 vertebral fractures per patient) versus a most severe non-vertebral phenotype (hip and femoral neck fractures mostly requiring surgery). Potential contributors varied: smoking (1/3–1/2 of subjects), family history of osteoporosis (1/3), heparin and glucocorticoid use in pregnancy, low body mass index (majority of cases), hypovitaminosis D; and (with a low level of statistical significance) anti-psychotic medication, gestational diabetes, lupus, thrombophilia, anemia, in vitro fertilization (1/3 in one study), twin pregnancy, tocolysis with MgSO4, and postpartum thyroiditis. Most remarkably, up to 50% of PLO patients harbor mutations of LRP5, WNT1 , and COL1A1/A2 (more damaged form with potential benefits from osteoanabolic drugs); gene testing might become the new norm in PLO. The low index of clinical suspicion should be supported by performing magnetic resonance imaging (gold standard in pregnancy) with DXA (in lactation). Low bone mineral density is expected (Z-score varying from −2.2 SD to −4 SD, unless normal which does not exclude PLO). Bone turnover markers might be useful in individuals with normal DXA, in pregnancy when DXA cannot be performed, and in following the response to anti-osteoporosis drugs. Alternatively, microarchitecture damage might be reflected by DXA-trabecular bone score and high-resolution peripheral quantitative computed tomography. Specific medical interventions are currently focused on teriparatide (TPT) use (3 studies; n = 99 females treated with TPT and an additional subgroup of 18 patients from the gene-analysis-based study, thus a total of 117 females) which seems to be the therapy of choice as reflected by these new data: 6–24 months, 20 µg/day, no sequential therapy needed; case selection based on high fracture risk is necessary). The first case using romosozumab was reported in 2022. PAO/LAO remains a challenging condition which is a battle for the wellbeing of two individuals, on one hand, considering maternal-fetal outcomes and taking care of the offspring, but it is a battle for a multidisciplinary team, on the other hand, since a standardized approach is lacking. Early diagnosis of pregnancy- and lactation-associated osteoporosis (PLO) is mandatory for a good outcome. Standard care is not a matter of conventional guidelines, rather it requires an individualized strategy while true overall incidence and pathogeny remain open issues. This is a narrative review based on full-length English articles, published between January 2021 and March 2023 and accessed via PubMed (no traumatic fractures or secondary osteoporosis are included). Our case-sample-based analysis included 836 females with PLO (the largest cohort based on published cases so far) through 12 studies and 24 single case reports. Except for one survey, these involved retrospective cohorts of small size (6-10 females/study) to medium size (23-47 women/study), and large cohorts with >50 subjects per study (a maximum of 379). Age of diagnosis: from 24 to 40 years for case reports (most subjects being over 30 and primigravida), while original studies indicated an average age between 31 and 34.18 years. Type of fractures underlined a most frequent vertebral phenotype (a mean of 2 to 5.8 vertebral fractures per patient) versus a most severe non-vertebral phenotype (hip and femoral neck fractures mostly requiring surgery). Potential contributors varied: smoking (1/3-1/2 of subjects), family history of osteoporosis (1/3), heparin and glucocorticoid use in pregnancy, low body mass index (majority of cases), hypovitaminosis D; and (with a low level of statistical significance) anti-psychotic medication, gestational diabetes, lupus, thrombophilia, anemia, in vitro fertilization (1/3 in one study), twin pregnancy, tocolysis with MgSO4, and postpartum thyroiditis. Most remarkably, up to 50% of PLO patients harbor mutations of LRP5, WNT1, and COL1A1/A2 (more damaged form with potential benefits from osteoanabolic drugs); gene testing might become the new norm in PLO. The low index of clinical suspicion should be supported by performing magnetic resonance imaging (gold standard in pregnancy) with DXA (in lactation). Low bone mineral density is expected (Z-score varying from -2.2 SD to -4 SD, unless normal which does not exclude PLO). Bone turnover markers might be useful in individuals with normal DXA, in pregnancy when DXA cannot be performed, and in following the response to anti-osteoporosis drugs. Alternatively, microarchitecture damage might be reflected by DXA-trabecular bone score and high-resolution peripheral quantitative computed tomography. Specific medical interventions are currently focused on teriparatide (TPT) use (3 studies; n = 99 females treated with TPT and an additional subgroup of 18 patients from the gene-analysis-based study, thus a total of 117 females) which seems to be the therapy of choice as reflected by these new data: 6-24 months, 20 µg/day, no sequential therapy needed; case selection based on high fracture risk is necessary). The first case using romosozumab was reported in 2022. PAO/LAO remains a challenging condition which is a battle for the wellbeing of two individuals, on one hand, considering maternal-fetal outcomes and taking care of the offspring, but it is a battle for a multidisciplinary team, on the other hand, since a standardized approach is lacking.Early diagnosis of pregnancy- and lactation-associated osteoporosis (PLO) is mandatory for a good outcome. Standard care is not a matter of conventional guidelines, rather it requires an individualized strategy while true overall incidence and pathogeny remain open issues. This is a narrative review based on full-length English articles, published between January 2021 and March 2023 and accessed via PubMed (no traumatic fractures or secondary osteoporosis are included). Our case-sample-based analysis included 836 females with PLO (the largest cohort based on published cases so far) through 12 studies and 24 single case reports. Except for one survey, these involved retrospective cohorts of small size (6-10 females/study) to medium size (23-47 women/study), and large cohorts with >50 subjects per study (a maximum of 379). Age of diagnosis: from 24 to 40 years for case reports (most subjects being over 30 and primigravida), while original studies indicated an average age between 31 and 34.18 years. Type of fractures underlined a most frequent vertebral phenotype (a mean of 2 to 5.8 vertebral fractures per patient) versus a most severe non-vertebral phenotype (hip and femoral neck fractures mostly requiring surgery). Potential contributors varied: smoking (1/3-1/2 of subjects), family history of osteoporosis (1/3), heparin and glucocorticoid use in pregnancy, low body mass index (majority of cases), hypovitaminosis D; and (with a low level of statistical significance) anti-psychotic medication, gestational diabetes, lupus, thrombophilia, anemia, in vitro fertilization (1/3 in one study), twin pregnancy, tocolysis with MgSO4, and postpartum thyroiditis. Most remarkably, up to 50% of PLO patients harbor mutations of LRP5, WNT1, and COL1A1/A2 (more damaged form with potential benefits from osteoanabolic drugs); gene testing might become the new norm in PLO. The low index of clinical suspicion should be supported by performing magnetic resonance imaging (gold standard in pregnancy) with DXA (in lactation). Low bone mineral density is expected (Z-score varying from -2.2 SD to -4 SD, unless normal which does not exclude PLO). Bone turnover markers might be useful in individuals with normal DXA, in pregnancy when DXA cannot be performed, and in following the response to anti-osteoporosis drugs. Alternatively, microarchitecture damage might be reflected by DXA-trabecular bone score and high-resolution peripheral quantitative computed tomography. Specific medical interventions are currently focused on teriparatide (TPT) use (3 studies; n = 99 females treated with TPT and an additional subgroup of 18 patients from the gene-analysis-based study, thus a total of 117 females) which seems to be the therapy of choice as reflected by these new data: 6-24 months, 20 µg/day, no sequential therapy needed; case selection based on high fracture risk is necessary). The first case using romosozumab was reported in 2022. PAO/LAO remains a challenging condition which is a battle for the wellbeing of two individuals, on one hand, considering maternal-fetal outcomes and taking care of the offspring, but it is a battle for a multidisciplinary team, on the other hand, since a standardized approach is lacking.
Audience	Academic
Author	Buescu, Cristian Turturea, Ionut Florin Valea, Ana Turturea, Maria Roxana Nistor, Claudiu Carsote, Mara
AuthorAffiliation	3 Department of Endocrinology, Iuliu Hatieganu University of Medicine and Pharmacy & Clinical County Hospital, 400347 Cluj-Napoca, Romania; ana74us@yahoo.com 4 Department of Orthopedics and Traumatology, Cluj Emergency County Hospital, 400347 Cluj-Napoca, Romania; cristibue@yahoo.com (C.B.); ionutturturea@gmail.com (I.F.T.) 2 Department of Endocrinology, Dej City Hospital, 405200 Dej, Romania; mariaroxanaturturea@gmail.com 5 Department 4—Cardio-Thoracic Pathology, Thoracic Surgery II Discipline, Carol Davila University of Medicine and Pharmacy & Thoracic Surgery Department, Dr. Carol Davila Central Emergency University Military Hospital, 011683 Bucharest, Romania; ncd58@yahoo.com 1 Department of Endocrinology, Carol Davila University of Medicine and Pharmacy & C.I. Parhon National Institute of Endocrinology, 011683 Bucharest, Romania
AuthorAffiliation_xml	– name: 2 Department of Endocrinology, Dej City Hospital, 405200 Dej, Romania; mariaroxanaturturea@gmail.com – name: 3 Department of Endocrinology, Iuliu Hatieganu University of Medicine and Pharmacy & Clinical County Hospital, 400347 Cluj-Napoca, Romania; ana74us@yahoo.com – name: 5 Department 4—Cardio-Thoracic Pathology, Thoracic Surgery II Discipline, Carol Davila University of Medicine and Pharmacy & Thoracic Surgery Department, Dr. Carol Davila Central Emergency University Military Hospital, 011683 Bucharest, Romania; ncd58@yahoo.com – name: 1 Department of Endocrinology, Carol Davila University of Medicine and Pharmacy & C.I. Parhon National Institute of Endocrinology, 011683 Bucharest, Romania – name: 4 Department of Orthopedics and Traumatology, Cluj Emergency County Hospital, 400347 Cluj-Napoca, Romania; cristibue@yahoo.com (C.B.); ionutturturea@gmail.com (I.F.T.)
Author_xml	– sequence: 1 givenname: Mara orcidid: 0000-0001-8585-3835 surname: Carsote fullname: Carsote, Mara – sequence: 2 givenname: Maria Roxana surname: Turturea fullname: Turturea, Maria Roxana – sequence: 3 givenname: Ana orcidid: 0000-0002-2266-2916 surname: Valea fullname: Valea, Ana – sequence: 4 givenname: Cristian surname: Buescu fullname: Buescu, Cristian – sequence: 5 givenname: Claudiu orcidid: 0000-0002-2274-5666 surname: Nistor fullname: Nistor, Claudiu – sequence: 6 givenname: Ionut Florin surname: Turturea fullname: Turturea, Ionut Florin
BackLink	https://www.ncbi.nlm.nih.gov/pubmed/37175006$$D View this record in MEDLINE/PubMed
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Cites_doi	10.1016/S0140-6736(55)90214-2 10.1177/09612033221136102 10.1007/s00223-021-00869-6 10.1007/s00198-021-06206-9 10.1007/s00277-021-04697-4 10.1001/jama.2016.12126 10.1007/s00223-021-00815-6 10.1371/journal.pmed.1004087 10.1016/j.ejogrb.2021.05.007 10.1080/13697137.2021.1926974 10.3390/ijms23031633 10.1093/ajcn/nqab264 10.1016/j.jos.2020.07.021 10.1007/s00198-019-05073-9 10.3892/etm.2021.10391 10.1111/cen.14641 10.2174/1574888X15999200729162502 10.1210/endrev/bnac031 10.3390/nu13072302 10.1007/s11657-021-00908-7 10.1136/bcr-2021-247967 10.1177/09612033221094710 10.1016/j.bone.2021.115911 10.1051/sicotj/2022045 10.1007/s11914-019-00555-5 10.3390/ijms222413662 10.1016/j.midw.2022.103468 10.1186/s12905-021-01298-1 10.3390/medicina59010019 10.1136/bcr-2020-238477 10.1016/j.tjog.2021.11.017 10.1016/j.jceh.2020.06.010 10.23736/S2724-606X.21.04893-4 10.1007/s13224-021-01512-y 10.1038/s41574-022-00742-y 10.1007/s11914-022-00734-x 10.1016/j.bone.2021.116253 10.1093/nutrit/nuaa138 10.1007/s00223-021-00871-y 10.29271/jcpsp.2021.Supp2.S127 10.1007/s00198-019-05236-8 10.1080/14767058.2023.2175659 10.1080/10408398.2022.2046542 10.1186/s13023-021-02148-x 10.1007/s00198-020-05754-w 10.1530/EC-20-0167 10.1016/j.bonr.2021.101071 10.1097/MD.0000000000027615 10.3390/nu14061168 10.1016/j.bone.2021.116133 10.1186/s12905-022-01662-9 10.1007/s00198-021-06250-5 10.1007/s00198-021-06008-z 10.11005/jbm.2021.28.2.115 10.1016/j.bone.2021.116177 10.1016/j.ijscr.2021.106197 10.1016/j.tem.2021.05.005 10.3904/kjim.2021.243 10.1007/s00198-019-04842-w 10.3390/nu14091900 10.1210/jc.2013-1172 10.1002/jbmr.4623 10.2147/IJGM.S278536 10.1007/s00393-021-01025-z 10.1007/s00198-020-05788-0 10.1055/a-1816-6700 10.1210/clinem/dgac719 10.1001/jamanetworkopen.2020.30405 10.1249/JSR.0000000000000813 10.1007/s00223-023-01066-3 10.1210/clinem/dgaa489 10.3390/nu14163351 10.5603/GP.a2021.0236 10.1177/1759720X211006979 10.1016/j.jocd.2015.06.008 10.1007/s00404-018-4742-4 10.1097/MD.0000000000008671 10.3389/fendo.2022.1016613 10.4103/JMAU.JMAU_9_20 10.2174/1871530320666201007151331 10.1080/13697137.2021.2011197 10.1002/jbm4.10651 10.2106/JBJS.RVW.22.00005 10.1053/j.ro.2020.09.002 10.3389/fphys.2023.1121579 10.3390/medicina58091242 10.1177/1759720X221133429 10.1007/s00192-020-04441-y 10.1007/s00198-022-06324-y 10.1186/s12891-021-04776-7 10.3389/fendo.2022.918682 10.1186/s12905-021-01516-w 10.1089/jwh.2020.8989 10.1177/1759720X231152648 10.1007/s00592-022-01907-x 10.1007/s00296-008-0641-5 10.1016/j.ajogmf.2021.100362 10.1007/s00256-016-2363-1 10.1007/s11657-021-01023-3 10.3390/ijms23169465 10.5387/fms.2014-14 10.1210/jendso/bvab031 10.1007/s00774-022-01336-4 10.3961/jpmph.21.162 10.1002/jbmr.4677 10.1007/s00223-021-00885-6 10.5606/tftrd.2021.4947 10.1056/NEJMoa2204091 10.14740/jmc3833 10.1016/j.crwh.2022.e00400 10.1007/s11657-022-01077-x 10.1177/08465371211015657 10.1111/nyas.14758 10.1097/BOR.0000000000000400 10.1016/j.crtox.2022.100066 10.4103/jfmpc.jfmpc_2349_20 10.1136/bcr-2020-238659 10.1007/s11657-020-00768-7 10.1111/jog.14694
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Keywords	romosozumab calcium teripartide lactation pregnancy vertebral bisphosphonates osteoporosis hip fracture
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References	Bhakta (ref_51) 2022; 34 Sifrig (ref_54) 2021; 20 Curtis (ref_30) 2021; 114 Hadji (ref_40) 2022; 82 Yang (ref_37) 2021; 16 ref_12 Grizzo (ref_82) 2020; 31 ref_10 Corbaz (ref_68) 2021; 14 Scott (ref_99) 2019; 30 Silva (ref_131) 2015; 18 ref_97 ref_95 ref_19 ref_18 ref_15 Saad (ref_100) 2022; 33 Scioscia (ref_47) 2021; 5 Toba (ref_41) 2022; 40 Hannan (ref_81) 2023; 19 Cohen (ref_135) 2013; 98 Ciuche (ref_111) 2012; 107 Woolford (ref_24) 2022; 37 Zhong (ref_129) 2021; 32 ref_29 ref_28 Sabaghzadeh (ref_112) 2022; 10 Stumpf (ref_66) 2021; 32 Varming (ref_57) 2022; 184 Langdahl (ref_85) 2017; 29 Huguet (ref_1) 2022; 69 Wang (ref_87) 2020; 13 Salamanna (ref_127) 2021; 32 Bhatnagar (ref_94) 2022; 14 Campopiano (ref_62) 2022; 13 Aytar (ref_42) 2022; 32 Ferreira (ref_61) 2022; 31 Crowther (ref_90) 2022; 387 Shlisky (ref_33) 2022; 1512 Curtin (ref_26) 2022; 33 Chen (ref_128) 2022; 61 ref_74 Rao (ref_107) 2021; 3 Kubihal (ref_92) 2022; 96 Violi (ref_122) 2021; 73 Bouzhir (ref_93) 2022; 82 Moon (ref_31) 2021; 13 Ishida (ref_88) 2022; 31 Pipitone (ref_113) 2021; 32 Rickert (ref_69) 2022; 10 Zillikens (ref_35) 2022; 110 Trovas (ref_45) 2021; 109 Klimko (ref_56) 2021; 13 Panahi (ref_132) 2021; 14 Vita (ref_105) 2021; 21 Vaajala (ref_91) 2022; 59 Conradie (ref_36) 2022; 25 Treurniet (ref_58) 2023; 112 ref_89 Laban (ref_27) 2021; 9 Ray (ref_125) 2016; 316 Ofluoglu (ref_7) 2008; 29 Percival (ref_22) 2021; 16 Ito (ref_133) 2021; 153 Ergen (ref_49) 2021; 32 Kawashima (ref_72) 2023; 28 Bilezikian (ref_17) 2022; 37 Curtis (ref_25) 2022; 6 Wright (ref_55) 2021; 14 Chaniotakis (ref_32) 2021; 21 Cohen (ref_21) 2022; 154 Butscheidt (ref_48) 2021; 147 Laldinsangi (ref_20) 2022; 3 Cohen (ref_134) 2020; 105 Nordin (ref_6) 1955; 268 (ref_86) 2021; 67 Bilezikian (ref_120) 2023; 108 Vasanwala (ref_5) 2022; 25 Philip (ref_50) 2022; 72 ref_60 Iio (ref_64) 2022; 13 Kurabayashi (ref_16) 2021; 47 Yoo (ref_11) 2021; 4 Hardcastle (ref_8) 2022; 110 Siva (ref_23) 2022; 15 Quaresima (ref_53) 2021; 262 Nistor (ref_130) 2021; 22 Awosanya (ref_119) 2022; 20 Takahashi (ref_126) 2014; 60 Sahin (ref_73) 2021; 31 Wu (ref_71) 2021; 32 Mouchantaf (ref_114) 2021; 85 Hourston (ref_63) 2022; 32 Zhang (ref_84) 2017; 96 Jadhav (ref_59) 2022; 14 Watts (ref_34) 2021; 30 Gaggiano (ref_52) 2022; 33 Liao (ref_98) 2022; 13 Iolascon (ref_117) 2022; 14 Liu (ref_83) 2019; 17 Koumakis (ref_108) 2022; 17 ref_115 Kapadia (ref_124) 2022; 73 Han (ref_65) 2021; 100 ref_118 Seo (ref_13) 2021; 54 Kong (ref_123) 2021; 28 Michalska (ref_70) 2022; 93 Venturella (ref_136) 2018; 298 Miles (ref_44) 2021; 13 Lee (ref_46) 2021; 109 Hardcastle (ref_79) 2019; 30 Condon (ref_43) 2022; 115 Choudhary (ref_102) 2021; 11 Lykking (ref_106) 2022; 154 Capozzi (ref_80) 2021; 73 (ref_14) 2022; 17 Veloso (ref_116) 2021; 11 Massari (ref_121) 2023; 15 Tayne (ref_78) 2019; 3 Athonvarangkul (ref_4) 2023; 14 Shaki (ref_9) 2021; 10 Virot (ref_104) 2022; 101 Cain (ref_110) 2021; 56 Brancatella (ref_96) 2020; 9 ref_101 ref_2 (ref_39) 2022; 57 Schorr (ref_75) 2016; 45 Eshed (ref_38) 2023; 36 Jia (ref_77) 2020; 15 Wawrzyniak (ref_3) 2021; 79 Factor (ref_76) 2022; 8 Kim (ref_109) 2022; 37 Bai (ref_67) 2021; 16 Leipe (ref_103) 2021; 80
References_xml	– volume: 268 start-page: 431 year: 1955 ident: ref_6 article-title: Post-pregnancy osteoporosis; a syndrome? publication-title: Lancet doi: 10.1016/S0140-6736(55)90214-2 – volume: 184 start-page: V05220334 year: 2022 ident: ref_57 article-title: Hip fracture in a pregnant woman publication-title: Ugeskr. Laeger. – volume: 31 start-page: 1829 year: 2022 ident: ref_61 article-title: Pregnancy and lactation-associated osteoporosis in a Systemic Lupus Erythematosus patient publication-title: Lupus doi: 10.1177/09612033221136102 – volume: 109 start-page: 544 year: 2021 ident: ref_46 article-title: Bone Density After Teriparatide Discontinuation With or Without Antiresorptive Therapy in Pregnancy- and Lactation-Associated Osteoporosis publication-title: Calcif. Tissue Int. doi: 10.1007/s00223-021-00869-6 – volume: 33 start-page: 511 year: 2022 ident: ref_100 article-title: Fracture risk following bariatric surgery: A systematic review and meta-analysis publication-title: Osteoporos. Int. doi: 10.1007/s00198-021-06206-9 – volume: 101 start-page: 289 year: 2022 ident: ref_104 article-title: Pregnancy outcome in women with transfused beta-thalassemia in France publication-title: Ann. Hematol. doi: 10.1007/s00277-021-04697-4 – volume: 316 start-page: 952 year: 2016 ident: ref_125 article-title: Association Between MRI Exposure During Pregnancy and Fetal and Childhood Outcomes publication-title: JAMA doi: 10.1001/jama.2016.12126 – volume: 110 start-page: 531 year: 2022 ident: ref_8 article-title: Pregnancy and Lactation Associated Osteoporosis publication-title: Calcif. Tissue. Int. doi: 10.1007/s00223-021-00815-6 – ident: ref_89 doi: 10.1371/journal.pmed.1004087 – volume: 262 start-page: 28 year: 2021 ident: ref_53 article-title: Pregnancy associated transient osteoporosis of the hip (PR-TOH): A non-obstetric indication to caesarean section. A case report with literature review publication-title: Eur. J. Obs. Gynecol. Reprod. Biol. doi: 10.1016/j.ejogrb.2021.05.007 – volume: 25 start-page: 73 year: 2022 ident: ref_36 article-title: Premenopausal osteoporosis publication-title: Climacteric doi: 10.1080/13697137.2021.1926974 – ident: ref_15 doi: 10.3390/ijms23031633 – volume: 114 start-page: 1600 year: 2021 ident: ref_30 article-title: MAVIDOS Trial Group. Bone turnover in pregnancy, measured by urinary CTX, is influenced by vitamin D supplementation and is associated with maternal bone health: Findings from the Maternal Vitamin D Osteoporosis Study (MAVIDOS) trial publication-title: Am. J. Clin. Nutr. doi: 10.1093/ajcn/nqab264 – volume: 28 start-page: 503 year: 2023 ident: ref_72 article-title: Pregnancy and lactation-associated vertebral fragility fractures without low bone mineral density: A case report publication-title: J. Orthop. Sci. doi: 10.1016/j.jos.2020.07.021 – volume: 30 start-page: 2151 year: 2019 ident: ref_99 article-title: Multiple vertebral compression fractures after sleeve gastrectomy and a subsequent pregnancy: A case report publication-title: Osteoporos. Int. doi: 10.1007/s00198-019-05073-9 – volume: 22 start-page: 959 year: 2021 ident: ref_130 article-title: Attitude of the surgical approach in hyperparathyroidism: A retrospective study publication-title: Exp Ther Med. doi: 10.3892/etm.2021.10391 – volume: 96 start-page: 531 year: 2022 ident: ref_92 article-title: Bone microarchitecture, bone mineral density and bone turnover in association with glycemia and insulin action in women with prior gestational diabetes publication-title: Clin. Endocrinol. Oxf. doi: 10.1111/cen.14641 – volume: 16 start-page: 688 year: 2021 ident: ref_37 article-title: Challenges in the Management of Pregnancy and Lactation Associated Osteoporosis: Literature Review and Retrospective Study publication-title: Curr. Stem. Cell Res. doi: 10.2174/1574888X15999200729162502 – ident: ref_29 doi: 10.1210/endrev/bnac031 – volume: 3 start-page: e037 year: 2019 ident: ref_78 article-title: Atraumatic Displaced Femoral Neck Fracture Postpartum: A Case Report and Review of the Literature publication-title: J. Am. Acad. Orthop. Surg. Glob. Res. Rev. – ident: ref_10 doi: 10.3390/nu13072302 – volume: 32 start-page: 260 year: 2022 ident: ref_63 article-title: Unusual presentation of atraumatic insufficiency pelvic fractures unmasking pregnancy-related osteoporosis: A case report publication-title: J. Perioper. Pract. – volume: 16 start-page: 36 year: 2021 ident: ref_67 article-title: Malleolar fracture in pregnancy and lactation-associated osteoporosis: A case report and literature review publication-title: Arch. Osteoporos. doi: 10.1007/s11657-021-00908-7 – volume: 15 start-page: e247967 year: 2022 ident: ref_23 article-title: Bilateral atraumatic femoral neck fractures resulting from transient osteoporosis of the hip publication-title: BMJ Case Rep. doi: 10.1136/bcr-2021-247967 – volume: 31 start-page: 848 year: 2022 ident: ref_88 article-title: Low pre-pregnant body mass index is a risk factor for the decrease of postpartum bone mineral density in systemic lupus erythematosus patients received glucocorticoid therapy publication-title: Lupus doi: 10.1177/09612033221094710 – volume: 147 start-page: 115911 year: 2021 ident: ref_48 article-title: Relevant genetic variants are common in women with pregnancy and lactation-associated osteoporosis (PLO) and predispose to more severe clinical manifestations publication-title: Bone doi: 10.1016/j.bone.2021.115911 – volume: 8 start-page: 44 year: 2022 ident: ref_76 article-title: Displaced femoral neck fracture in a pregnant patient diagnosed with transient osteoporosis of the hip publication-title: SICOT J. doi: 10.1051/sicotj/2022045 – volume: 17 start-page: 375 year: 2019 ident: ref_83 article-title: Mechanical Regulation of the Maternal Skeleton during Reproduction and Lactation publication-title: Curr. Osteoporos. Rep. doi: 10.1007/s11914-019-00555-5 – ident: ref_101 doi: 10.3390/ijms222413662 – volume: 115 start-page: 103468 year: 2022 ident: ref_43 article-title: The experience of pregnancy associated osteoporosis: An international survey with implications for midwifery care publication-title: Midwifery doi: 10.1016/j.midw.2022.103468 – volume: 10 start-page: e39 year: 2022 ident: ref_112 article-title: Orthopedic Trauma During Pregnancy; a Narrative Review publication-title: Arch Acad. Emerg. Med. – ident: ref_115 doi: 10.1186/s12905-021-01298-1 – volume: 14 start-page: e31322 year: 2022 ident: ref_59 article-title: Pregnancy- and Lactation-Associated Osteoporotic Vertebral Fracture: A Case Report publication-title: Cureus – ident: ref_60 doi: 10.3390/medicina59010019 – volume: 14 start-page: e238477 year: 2021 ident: ref_68 article-title: Lower lumbar back pain occurring with transient hip osteoporosis: Complication of prolonged suffering and neck of femur fracture in a 24-year-old pregnant patient publication-title: BMJ Case Rep. doi: 10.1136/bcr-2020-238477 – volume: 61 start-page: 91 year: 2022 ident: ref_128 article-title: Association between P1NP and bone strength in postmenopausal women treated with teriparatide publication-title: Taiwan J. Obs. Gynecol. doi: 10.1016/j.tjog.2021.11.017 – volume: 11 start-page: 239 year: 2021 ident: ref_102 article-title: Long-term Management of the Adult Liver Transplantation Recipients publication-title: J. Clin. Exp. Hepatol. doi: 10.1016/j.jceh.2020.06.010 – volume: 73 start-page: 754 year: 2021 ident: ref_122 article-title: Rethinking of osteoporosis through a sex- and gender-informed approach in the COVID-19 era publication-title: Minerva. Obstet. Gynecol. doi: 10.23736/S2724-606X.21.04893-4 – volume: 72 start-page: 346 year: 2022 ident: ref_50 article-title: Transient Osteoporosis of Hip Causing Fracture Neck of Femur in Pregnancy publication-title: J. Obs. Gynaecol. India doi: 10.1007/s13224-021-01512-y – volume: 19 start-page: 46 year: 2023 ident: ref_81 article-title: Hormonal regulation of mammary gland development and lactation publication-title: Nat. Rev. Endocrinol. doi: 10.1038/s41574-022-00742-y – volume: 20 start-page: 213 year: 2022 ident: ref_119 article-title: The Impacts of COVID-19 on Musculoskeletal Health publication-title: Curr. Osteoporos. Rep. doi: 10.1007/s11914-022-00734-x – volume: 13 start-page: e19011 year: 2021 ident: ref_44 article-title: Analysis of Fracture Incidence in 135 Patients With Pregnancy and Lactation Osteoporosis (PLO) publication-title: Cureus – volume: 154 start-page: 116253 year: 2022 ident: ref_21 article-title: Whole exome sequencing reveals potentially pathogenic variants in a small subset of premenopausal women with idiopathic osteoporosis publication-title: Bone doi: 10.1016/j.bone.2021.116253 – volume: 79 start-page: 1307 year: 2021 ident: ref_3 article-title: Nutritional and health factors affecting the bioavailability of calcium: A narrative review publication-title: Nutr. Rev. doi: 10.1093/nutrit/nuaa138 – volume: 109 start-page: 554 year: 2021 ident: ref_45 article-title: Teriparatide Treatment in Patients with Pregnancy- and Lactation-Associated Osteoporosis publication-title: Calcif. Tissue Int. doi: 10.1007/s00223-021-00871-y – volume: 31 start-page: S127 year: 2021 ident: ref_73 article-title: Sacral Stress Fracture due to Excess Weight Gain during Pregnancy while Self-Quarantining during the COVID-19 Pandemic publication-title: J. Coll. Physicians. Surg. Pak. doi: 10.29271/jcpsp.2021.Supp2.S127 – volume: 31 start-page: 413 year: 2020 ident: ref_82 article-title: How does women’s bone health recover after lactation? A systematic review and meta-analysis publication-title: Osteoporos. Int. doi: 10.1007/s00198-019-05236-8 – volume: 36 start-page: 2175659 year: 2023 ident: ref_38 article-title: Transient osteoporosis of the hip in pregnancy—A case series publication-title: J. Matern Fetal Neonatal. Med. doi: 10.1080/14767058.2023.2175659 – ident: ref_97 doi: 10.1080/10408398.2022.2046542 – volume: 17 start-page: 22 year: 2022 ident: ref_108 article-title: Osteogenesis Imperfecta: Characterization of fractures during pregnancy and post-partum publication-title: Orphanet. J. Rare. Dis. doi: 10.1186/s13023-021-02148-x – volume: 32 start-page: 981 year: 2021 ident: ref_49 article-title: Pregnancy- and lactation-associated vertebral compression fractures: MRI prevalence and characteristics publication-title: Osteoporos. Int. doi: 10.1007/s00198-020-05754-w – volume: 57 start-page: 269 year: 2022 ident: ref_39 article-title: Pregnancy-Related Sacral Stress Fractures: A Single Center Experience of 23 Cases publication-title: Indian J. Orthop. – volume: 9 start-page: R158 year: 2020 ident: ref_96 article-title: TSH suppressive therapy and bone publication-title: Endocr. Connect. doi: 10.1530/EC-20-0167 – volume: 14 start-page: 101071 year: 2021 ident: ref_132 article-title: Grand multiparity associations with low bone mineral density and degraded trabecular bone pattern publication-title: Bone Rep. doi: 10.1016/j.bonr.2021.101071 – volume: 32 start-page: 323 year: 2022 ident: ref_42 article-title: Management of Pregnancy-and Lactation-Related Osteoporosis: Case Series publication-title: Turk. Neurosurg. – volume: 100 start-page: e27615 year: 2021 ident: ref_65 article-title: Post-pregnancy osteoporosis-related multiple vertebral fractures associated with post-partum thyroiditis: A CARE-compliant case report publication-title: Medicine doi: 10.1097/MD.0000000000027615 – ident: ref_19 doi: 10.3390/nu14061168 – volume: 153 start-page: 116133 year: 2021 ident: ref_133 article-title: Transient alendronate administration to pregnant or lactating mothers prevents bone loss in mice without adverse effects on offspring publication-title: Bone doi: 10.1016/j.bone.2021.116133 – ident: ref_12 doi: 10.1186/s12905-022-01662-9 – volume: 33 start-page: 1165 year: 2022 ident: ref_26 article-title: No effect of maternal calcium intake and bone resorption during pregnancy on offspring bone mineral density at age 5 years publication-title: Osteoporos. Int. doi: 10.1007/s00198-021-06250-5 – volume: 32 start-page: 2383 year: 2021 ident: ref_66 article-title: Influence of denosumab on bone mineral density in a severe case of pregnancy-associated osteoporosis publication-title: Osteoporos. Int. doi: 10.1007/s00198-021-06008-z – volume: 28 start-page: 115 year: 2021 ident: ref_123 article-title: The Impact of COVID-19 on the Optimal Management of Osteoporosis publication-title: J. Bone Metab. doi: 10.11005/jbm.2021.28.2.115 – volume: 32 start-page: 149 year: 2021 ident: ref_129 article-title: Advances in Bone Turnover Markers (PINP and CTX) in Optimizing Anti-resorptive and Anabolic Therapies Against Osteoporosis publication-title: Discov. Med. – volume: 154 start-page: 116177 year: 2022 ident: ref_106 article-title: Fractures following pregnancy in Osteogenesis imperfecta—A self-controlled case series using Danish Health Registers publication-title: Bone doi: 10.1016/j.bone.2021.116177 – volume: 85 start-page: 106197 year: 2021 ident: ref_114 article-title: Hip avascular necrosis in a healthy pregnant woman: A case report and review of literature publication-title: Int. J. Surg. Case Rep. doi: 10.1016/j.ijscr.2021.106197 – volume: 32 start-page: 672 year: 2021 ident: ref_127 article-title: Blood factors as biomarkers in osteoporosis: Points from the COVID-19 era publication-title: Trends Endocrinol. Metab. doi: 10.1016/j.tem.2021.05.005 – volume: 37 start-page: 247 year: 2022 ident: ref_109 article-title: Cushing’s syndrome: A rare cause of multiple vertebral fractures shortly after a complicated pregnancy publication-title: Korean J. Intern. Med. doi: 10.3904/kjim.2021.243 – volume: 30 start-page: 939 year: 2019 ident: ref_79 article-title: Pregnancy-associated osteoporosis: A UK case series and literature review publication-title: Osteoporos. Int. doi: 10.1007/s00198-019-04842-w – ident: ref_2 doi: 10.3390/nu14091900 – volume: 98 start-page: 1971 year: 2013 ident: ref_135 article-title: Teriparatide for idiopathic osteoporosis in premenopausal women: A pilot study publication-title: J. Clin. Endocrinol. Metab. doi: 10.1210/jc.2013-1172 – volume: 37 start-page: 1511 year: 2022 ident: ref_24 article-title: ALPHABET Consortium Investigators. Associations Between Late Pregnancy Dietary Inflammatory Index (DII) and Offspring Bone Mass: A Meta-Analysis of the Southampton Women’s Survey (SWS) and the Avon Longitudinal Study of Parents and Children (ALSPAC) publication-title: J. Bone Min. Res. doi: 10.1002/jbmr.4623 – volume: 13 start-page: 1043 year: 2020 ident: ref_87 article-title: Barton Fracture of the Distal Radius in Pregnancy and Lactation-Associated Osteoporosis: A Case Report and Literature Review publication-title: Int. J. Gen. Med. doi: 10.2147/IJGM.S278536 – volume: 80 start-page: 49 year: 2021 ident: ref_103 article-title: German Society of Rheumatology recommendations for management of glucocorticoid-induced osteoporosis publication-title: Z. Rheumatol. doi: 10.1007/s00393-021-01025-z – volume: 32 start-page: 623 year: 2021 ident: ref_71 article-title: Postpartum bilateral sacral stress fracture without osteoporosis-a case report and literature review publication-title: Osteoporos. Int. doi: 10.1007/s00198-020-05788-0 – volume: 82 start-page: 619 year: 2022 ident: ref_40 article-title: Effect of Teriparatide on Subsequent Fracture and Bone Mineral Density in 47 Women with Pregnancy- and Lactation-associated Osteoporosis and Vertebral Fractures publication-title: Geburtshilfe. Frauenheilkd. doi: 10.1055/a-1816-6700 – volume: 108 start-page: 1034 year: 2023 ident: ref_120 article-title: Consensus and Controversial Aspects of Vitamin D and COVID-19 publication-title: J. Clin. Endocrinol. Metab. doi: 10.1210/clinem/dgac719 – volume: 4 start-page: e2030405 year: 2021 ident: ref_11 article-title: Association of Female Reproductive Factors With Incidence of Fracture Among Postmenopausal Women in Korea publication-title: JAMA Netw. Open. doi: 10.1001/jamanetworkopen.2020.30405 – volume: 20 start-page: 80 year: 2021 ident: ref_54 article-title: An Uncommon Cause of Debilitating Hip Pain in Pregnancy publication-title: Curr. Sport. Med. Rep. doi: 10.1249/JSR.0000000000000813 – volume: 112 start-page: 621 year: 2023 ident: ref_58 article-title: Bone Microarchitecture and Strength Changes During Teriparatide and Zoledronic Acid Treatment in a Patient with Pregnancy and Lactation-Associated Osteoporosis with Multiple Vertebral Fractures publication-title: Calcif. Tissue Int. doi: 10.1007/s00223-023-01066-3 – volume: 105 start-page: e3540 year: 2020 ident: ref_134 article-title: Effect of Teriparatide on Bone Remodeling and Density in Premenopausal Idiopathic Osteoporosis: A Phase II Trial publication-title: J. Clin. Endocrinol. Metab. doi: 10.1210/clinem/dgaa489 – ident: ref_18 doi: 10.3390/nu14163351 – volume: 93 start-page: 521 year: 2022 ident: ref_70 article-title: Fatigue fracture of the sacrum related to pregnancy publication-title: Ginekol. Pol. doi: 10.5603/GP.a2021.0236 – volume: 13 start-page: 1759720X211006979 year: 2021 ident: ref_31 article-title: The importance of maternal pregnancy vitamin D for offspring bone health: Learnings from the MAVIDOS trial publication-title: Ther. Adv. Musculoskelet. Dis. doi: 10.1177/1759720X211006979 – volume: 18 start-page: 309 year: 2015 ident: ref_131 article-title: Fracture Risk Prediction by Non-BMD DXA Measures: The 2015 ISCD Official Positions Part 2: Trabecular Bone Score publication-title: J. Clin. Densitom. doi: 10.1016/j.jocd.2015.06.008 – volume: 298 start-page: 9 year: 2018 ident: ref_136 article-title: Non-obstetrical indications for cesarean section: A state-of-the-art review publication-title: Arch Gynecol. Obs. doi: 10.1007/s00404-018-4742-4 – volume: 96 start-page: e8671 year: 2017 ident: ref_84 article-title: Approach to the patient with pregnancy and lactation-associated osteoporosis: A case report and a review of the literature publication-title: Medicine doi: 10.1097/MD.0000000000008671 – volume: 13 start-page: 1016613 year: 2022 ident: ref_98 article-title: Bariatric surgery and health outcomes: An umbrella analysis publication-title: Front. Endocrinol. Lausanne doi: 10.3389/fendo.2022.1016613 – volume: 11 start-page: 102 year: 2021 ident: ref_116 article-title: Chronic Anterior Pelvic Instability publication-title: J. Orthop. Case Rep. – volume: 69 start-page: 530 year: 2022 ident: ref_1 article-title: Guide of management of alterations in mineral and bone metabolism during gestation and lactation publication-title: Endocrinol. Diabetes Nutr. Engl. Ed. – volume: 9 start-page: 103 year: 2021 ident: ref_27 article-title: Bone Health Assessed by Calcaneal Quantitative Ultrasound among Cohort of Pregnant Egyptian Women publication-title: J. Microsc. Ultrastruct. doi: 10.4103/JMAU.JMAU_9_20 – volume: 82 start-page: 104569 year: 2022 ident: ref_93 article-title: Homozygous factor V leiden mutation: Rare etiology of pulmonary embolism publication-title: Ann. Med. Surg. Lond. – volume: 21 start-page: 1512 year: 2021 ident: ref_105 article-title: Conservative Management of Gestational Hypercalcemia Due to Primary Hyperparathyroidism with Lack of Complications publication-title: Endocr. Metab. Immune. Disord. Drug Targets doi: 10.2174/1871530320666201007151331 – volume: 25 start-page: 11 year: 2022 ident: ref_5 article-title: It starts from the womb: Maximizing bone health publication-title: Climacteric doi: 10.1080/13697137.2021.2011197 – volume: 6 start-page: e10651 year: 2022 ident: ref_25 article-title: MAVIDOS Trial Group. Pregnancy Vitamin D Supplementation and Childhood Bone Mass at Age 4 Years: Findings From the Maternal Vitamin D Osteoporosis Study (MAVIDOS) Randomized Controlled Trial publication-title: JBMR Plus doi: 10.1002/jbm4.10651 – volume: 10 start-page: e22.00005 year: 2022 ident: ref_69 article-title: Sacral Insufficiency Fractures publication-title: JBJS Rev. doi: 10.2106/JBJS.RVW.22.00005 – volume: 56 start-page: 79 year: 2021 ident: ref_110 article-title: Musculoskeletal Injuries in Pregnancy publication-title: Semin. Roentgenol. doi: 10.1053/j.ro.2020.09.002 – volume: 14 start-page: 1121579 year: 2023 ident: ref_4 article-title: Crosstalk within a brain-breast-bone axis regulates mineral and skeletal metabolism during lactation publication-title: Front. Physiol. doi: 10.3389/fphys.2023.1121579 – ident: ref_118 doi: 10.3390/medicina58091242 – volume: 14 start-page: 1759720X221133429 year: 2022 ident: ref_117 article-title: Bone fragility: Conceptual framework, therapeutic implications, and COVID-19-related issues publication-title: Adv. Musculoskelet. Dis. doi: 10.1177/1759720X221133429 – volume: 32 start-page: 1779 year: 2021 ident: ref_113 article-title: Musculoskeletal findings on MRI among postpartum women with persistent pelvic pain publication-title: Int. Urogynecol. J. doi: 10.1007/s00192-020-04441-y – volume: 33 start-page: 1619 year: 2022 ident: ref_52 article-title: Neridronate for transient osteoporosis of the hip in a child publication-title: Osteoporos Int. doi: 10.1007/s00198-022-06324-y – volume: 13 start-page: e19524 year: 2021 ident: ref_56 article-title: Unilateral Atraumatic Femoral Neck Fracture in the Peripartum Period: Case Report and Literature Review publication-title: Cureus – volume: 21 start-page: 332 year: 2021 ident: ref_32 article-title: Pregnancy associated osteoporotic vertebral fractures: An underdiagnosed condition of back pain publication-title: J. Musculoskelet. Neuronal. Interact. – ident: ref_74 doi: 10.1186/s12891-021-04776-7 – volume: 13 start-page: 918682 year: 2022 ident: ref_62 article-title: Case report: Early-onset osteoporosis in a patient carrying a novel heterozygous variant of the WNT1 gene publication-title: Front. Endocrinol. Lausanne. doi: 10.3389/fendo.2022.918682 – ident: ref_28 doi: 10.1186/s12905-021-01516-w – volume: 30 start-page: 1416 year: 2021 ident: ref_34 article-title: Bone Mineral Density Changes Associated With Pregnancy, Lactation, and Medical Treatments in Premenopausal Women and Effects Later in Life publication-title: J. Womens Health Larchmt doi: 10.1089/jwh.2020.8989 – volume: 14 start-page: e29367 year: 2022 ident: ref_94 article-title: Postmenopausal Osteoporosis: A Literature Review publication-title: Cureus – volume: 15 start-page: 1759720X231152648 year: 2023 ident: ref_121 article-title: Nutritional and physical activity issues in frailty syndrome during the COVID-19 pandemic publication-title: Ther. Adv. Musculoskelet. Dis. doi: 10.1177/1759720X231152648 – volume: 59 start-page: 1385 year: 2022 ident: ref_91 article-title: The effect of gestational diabetes on the fracture risk after pregnancy: A nationwide register-based study publication-title: Acta Diabetol. doi: 10.1007/s00592-022-01907-x – volume: 29 start-page: 197 year: 2008 ident: ref_7 article-title: A case report: Pregnancy-induced severe osteoporosis with eight vertebral fractures publication-title: Rheumatol. Int. doi: 10.1007/s00296-008-0641-5 – volume: 3 start-page: 100362 year: 2021 ident: ref_107 article-title: Pregnancy in women with osteogenesis imperfecta: Pregnancy characteristics, maternal, and neonatal outcomes publication-title: Am. J. Obs. Gynecol. MFM doi: 10.1016/j.ajogmf.2021.100362 – volume: 73 start-page: 697 year: 2021 ident: ref_80 article-title: Bone metabolism in pregnancy and lactation publication-title: Minerva Obs. Gynecol. – volume: 45 start-page: 813 year: 2016 ident: ref_75 article-title: Body composition predictors of skeletal integrity in obesity publication-title: Skelet. Radiol. doi: 10.1007/s00256-016-2363-1 – volume: 16 start-page: 159 year: 2021 ident: ref_22 article-title: Maternal vitamin D and offspring fracture risk: The Vitamin D in Pregnancy study publication-title: Arch Osteoporos. doi: 10.1007/s11657-021-01023-3 – ident: ref_95 doi: 10.3390/ijms23169465 – volume: 60 start-page: 175 year: 2014 ident: ref_126 article-title: Four-year follow-up of pregnancy-associated osteoporosis: A case report publication-title: Fukushima. J. Med. Sci. doi: 10.5387/fms.2014-14 – volume: 5 start-page: bvab031 year: 2021 ident: ref_47 article-title: Severe Bone Microarchitecture Impairment in Women With Pregnancy and Lactation-Associated Osteoporosis publication-title: J. Endocr. Soc. doi: 10.1210/jendso/bvab031 – volume: 40 start-page: 748 year: 2022 ident: ref_41 article-title: Fractures within 2 years of an obstetric hospitalization: Analysis of nationwide administrative data in Japan publication-title: J. Bone Min. Metab. doi: 10.1007/s00774-022-01336-4 – volume: 54 start-page: 284 year: 2021 ident: ref_13 article-title: Association Between Parity and Low Bone Density Among Postmenopausal Korean Women publication-title: J. Prev. Med. Public Health doi: 10.3961/jpmph.21.162 – volume: 37 start-page: 2293 year: 2022 ident: ref_17 article-title: International Workshop on Primary Hyperparathyroidism. Evaluation and Management of Primary Hyperparathyroidism: Summary Statement and Guidelines from the Fifth International Workshop publication-title: J. Bone Min. Res. doi: 10.1002/jbmr.4677 – volume: 110 start-page: 546 year: 2022 ident: ref_35 article-title: Early-Onset Osteoporosis publication-title: Calcif. Tissue. Int. doi: 10.1007/s00223-021-00885-6 – volume: 67 start-page: 254 year: 2021 ident: ref_86 article-title: Postpartum stress fracture of bilateral tibia: A case report publication-title: Turk. J. Phys. Med. Rehabil. doi: 10.5606/tftrd.2021.4947 – volume: 387 start-page: 587 year: 2022 ident: ref_90 article-title: GEMS Trial Group. Lower versus Higher Glycemic Criteria for Diagnosis of Gestational Diabetes publication-title: N. Engl. J. Med. doi: 10.1056/NEJMoa2204091 – volume: 13 start-page: 47 year: 2022 ident: ref_64 article-title: Long-Term Tocolysis With Magnesium Sulfate as a Risk Factor for Low Bone Mass: A Case Series publication-title: J. Med. Cases doi: 10.14740/jmc3833 – volume: 34 start-page: e00400 year: 2022 ident: ref_51 article-title: Transient osteoporosis in the third trimester of pregnancy: A case report publication-title: Case Rep. Womens Health doi: 10.1016/j.crwh.2022.e00400 – volume: 17 start-page: 36 year: 2022 ident: ref_14 article-title: Bone metabolism and osteoporosis during pregnancy and lactation publication-title: Arch Osteoporos. doi: 10.1007/s11657-022-01077-x – volume: 73 start-page: 56 year: 2022 ident: ref_124 article-title: Canadian Association of Radiologists Recommendations for the Safe Use of MRI During Pregnancy publication-title: Can. Assoc. Radiol. J. doi: 10.1177/08465371211015657 – volume: 1512 start-page: 10 year: 2022 ident: ref_33 article-title: Calcium deficiency worldwide: Prevalence of inadequate intakes and associated health outcomes publication-title: Ann. N. Y. Acad. Sci. doi: 10.1111/nyas.14758 – volume: 29 start-page: 410 year: 2017 ident: ref_85 article-title: Osteoporosis in premenopausal women publication-title: Curr. Opin. Rheumatol. doi: 10.1097/BOR.0000000000000400 – volume: 3 start-page: 100066 year: 2022 ident: ref_20 article-title: Toxic effects of smokeless tobacco on female reproductive health: A review publication-title: Curr. Res. Toxicol. doi: 10.1016/j.crtox.2022.100066 – volume: 10 start-page: 2886 year: 2021 ident: ref_9 article-title: Does parity and duration of lactation have any effect on the bone mineral density of the femur and lumbar spine in Indian women? A cross-sectional study from the Northeast region of India publication-title: J. Fam. Med. Prim. Care doi: 10.4103/jfmpc.jfmpc_2349_20 – volume: 107 start-page: 206 year: 2012 ident: ref_111 article-title: Minimally invasive surgery in the treatment of malignant pleuro-pericardial effusions publication-title: Chirurgia (Bucur). – volume: 14 start-page: e238659 year: 2021 ident: ref_55 article-title: Transient osteoporosis of the hip in pregnancy: The orthopaedic management of bilateral neck of femur fractures in the third trimester publication-title: BMJ Case Rep. doi: 10.1136/bcr-2020-238659 – volume: 15 start-page: 94 year: 2020 ident: ref_77 article-title: A case of pregnancy and lactation-associated osteoporosis and a review of the literature publication-title: Arch. Osteoporos. doi: 10.1007/s11657-020-00768-7 – volume: 47 start-page: 1388 year: 2021 ident: ref_16 article-title: Prevalence of osteoporosis and osteopenia assessed by densitometry in Japanese puerperal women publication-title: J. Obs. Gynaecol. Res. doi: 10.1111/jog.14694
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Snippet	Early diagnosis of pregnancy- and lactation-associated osteoporosis (PLO) is mandatory for a good outcome. Standard care is not a matter of conventional...
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SubjectTerms	Antipsychotic drugs Bone surgery Breastfeeding & lactation calcium Case reports Chronic illnesses Corticosteroids Denosumab fracture Fractures hip lactation Magnetic resonance imaging Metabolism Orthopedics Osteoporosis Physiology Pregnancy Pregnant women Review Surveys Vitamin D Vitamin deficiency
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Title	Bridging the Gap: Pregnancy—And Lactation—Associated Osteoporosis
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