Translating mouse models of abdominal aortic aneurysm to the translational needs of vascular surgery

• Published in: JVS-vascular science Vol. 2; pp. 219 - 234
• Main Authors: Busch, Albert, Bleichert, Sonja, Ibrahim, Nahla, Wortmann, Markus, Eckstein, Hans-Henning, Brostjan, Christine, Wagenhäuser, Markus U., Goergen, Craig J., Maegdefessel, Lars
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.01.2021; Elsevier
• Subjects: AAA; Abdominal aortic aneurysm; Aneurysm mouse models; Translational research; AAA; Translational research; Aneurysm mouse models; Abdominal aortic aneurysm

Abdominal aortic aneurysm (AAA) is a condition that has considerable socioeconomic impact and an eventual rupture is associated with high mortality and morbidity. Despite decades of research, surgical repair remains the treatment of choice and no medical therapy is currently available. Animal models...