LncRNA HOXB-AS3 promotes proliferation, migration, and invasion of gallbladder cancer cells by activating the MEK/ERK pathway

• Published in: Heliyon Vol. 10; no. 16; p. e35906
• Main Authors: Wu, Jiayan, Yu, Jiandong, Zhu, Hongquan, Chen, Zhiping, Liang, Yongling, Chen, Qin, Li, Guolin, Wan, Yunle
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 30.08.2024; Elsevier
• Subjects: agonists; apoptosis; cancer therapy; carcinogenesis; carcinoma; cell proliferation; cell viability; flow cytometry; gall bladder; Gallbladder carcinoma; HOXB-AS3; interphase; Long non coding RNA; MEK/ERK; metastasis; neoplasm cells; neoplasm progression; phosphorylation; quantitative polymerase chain reaction; xenotransplantation; LncRNA; Long non coding RNA; GBC; HOXB-AS3; MEK/ERK; Gallbladder carcinoma

LncRNA HOXB-AS3 are associated with tumor progression in several types of carcinomas, yet, its possibly biological role in gallbladder carcinoma(GBC) remains unclear. Therefore, this study aimed to investigate the biological function of HOXB-AS3 in GBC. To know the potential function of HOXB-AS3 in...