Platelet-rich plasma preparation for regenerative medicine: optimization and quantification of cytokines and growth factors

• Published in: Stem cell research & therapy Vol. 4; no. 3; p. 67
• Main Authors: Amable, Paola Romina, Carias, Rosana Bizon Vieira, Teixeira, Marcus Vinicius Telles, da Cruz Pacheco, Italo, Corrêa do Amaral, Ronaldo José Farias, Granjeiro, José Mauro, Borojevic, Radovan
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 07.06.2013; BioMed Central
• Subjects: Adult; Blood donors; Blood Platelets - cytology; Blood Platelets - metabolism; Centrifugation; Chemokines - metabolism; Cytokines; Cytokines - metabolism; Female; Growth factors; Humans; Intercellular Signaling Peptides and Proteins - metabolism; Interferon; Interleukins; Male; Middle Aged; Platelet-Rich Plasma; Regenerative Medicine; Stem cell research; Temperature; Time Factors; United States

Platelet-rich plasma (PRP) is nowadays widely applied in different clinical scenarios, such as orthopedics, ophthalmology and healing therapies, as a growth factor pool for improving tissue regeneration. Studies into its clinical efficiency are not conclusive and one of the main reasons for this is...