Effect of BMI and age on adipose tissue cellularity and differentiation capacity in women

• Published in: International Journal of Obesity Vol. 27; no. 8; pp. 889 - 895
• Main Authors: Harmelen, V. van, Skurk, T, Röhrig, K, Lee, Y.M, Halbleib, M, Aprath-Husmann, I, Hauner, H
• Format: Journal Article
• Language: English
• Published: Basingstoke Nature Publishing Group 01.08.2003; Nature Publishing
• Subjects: 1-Methyl-3-isobutylxanthine - pharmacology; Adipocytes; Adipocytes - cytology; Adipocytes - enzymology; Adipose tissue; Adipose Tissue - cytology; Adipose Tissue - enzymology; Adipose tissues; Adolescent; Adult; Age; Aged; Biological and medical sciences; Body fat; Body Mass Index; Cell Differentiation; Cells, Cultured; Chromans - pharmacology; correlation; Diabetes; Female; Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating) - metabolism; Glycerol; glycerol-3-phosphate dehydrogenase; Health aspects; Humans; Hyperplasia; Investigative techniques, diagnostic techniques (general aspects); Medical sciences; Metabolic diseases; Middle Aged; Obesity; Overweight; Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques; stromal cells; Stromal Cells - cytology; Thiazoles - pharmacology; Thiazolidinediones; women; Germany; Human; Body mass index; Adipose tissue; differentiation; human preadipocytes; Female; Preadipocyte; Thiazolidinedione derivatives; Woman; Age; Troglitazone

OBJECTIVE: To study the relation between body mass index (BMI) and age on the one hand and total number of human (pre-) adipocytes and preadipocyte differentiation capacity on the other hand. SUBJECTS: In total, 189 women undergoing surgical mammary reduction, age range 16-73 y, BMI range 19.7-39.7...