Fatigue and cognitive impairment in Post-COVID-19 Syndrome: A systematic review and meta-analysis

• Published in: Brain, behavior, and immunity Vol. 101; pp. 93 - 135
• Main Authors: Ceban, Felicia, Ling, Susan, Lui, Leanna M.W., Lee, Yena, Gill, Hartej, Teopiz, Kayla M., Rodrigues, Nelson B., Subramaniapillai, Mehala, Di Vincenzo, Joshua D., Cao, Bing, Lin, Kangguang, Mansur, Rodrigo B., Ho, Roger C., Rosenblat, Joshua D., Miskowiak, Kamilla W., Vinberg, Maj, Maletic, Vladimir, McIntyre, Roger S.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Inc 01.03.2022
• Subjects: Anhedonia; Bipolar; Brain; Brain fog; Cognition; Cognitive Dysfunction; Cognitive impairment; COVID-19; COVID-19 - complications; COVID-19 Testing; Depression; Fatigue; Fatigue - etiology; Functional outcomes; Humans; Immunology; Inflammation; Long COVID; Mental illness; Population health; Post-Acute COVID-19 Syndrome; Post-COVID-19 condition; Post-COVID-19 syndrome; Review; SARS-CoV-2; PCS; Brain; Post-COVID-19 condition; Post-COVID-19 syndrome; Brain fog; Functional outcomes; Fatigue; Depression; Anhedonia; Inflammation; Cognition; Long COVID; COVID-19; Bipolar; Immunology; Mental illness; Cognitive impairment; Population health

•Fatigue and cognitive impairment are amongst the most common and debilitating symptoms of post-COVID-19 syndrome.•Approximately 1 in 3 individuals experienced fatigue 12 or more weeks following COVID-19 diagnosis.•Approximately 1 in 5 individuals exhibited cognitive impairment 12 or more weeks foll...