Associations between Small Dense LDL, HDL Subfractions (HDL2, HDL3) and Risk of Atherosclerosis in Japanese-Americans

• Published in: Journal of Atherosclerosis and Thrombosis Vol. 19; no. 5; pp. 444 - 452
• Main Authors: Hirano, Tsutomu, Nakanishi, Shuhei, Maeda, Shusaku, Kohno, Nobuoki, Yoneda, Masayasu, Awaya, Tomokazu, Yamane, Kiminori
• Format: Journal Article
• Language: English
• Published: Japan Japan Atherosclerosis Society 01.01.2012
• Subjects: Aged; Asian Americans; Atherosclerosis - blood; Atherosclerosis - ethnology; Blood Glucose - analysis; Body Mass Index; Carotid artery intima-media thickness (IMT); Female; Glucose tolerance; High-density lipoprotein subfractions; Humans; Insulin - blood; Insulin Resistance; Japan - ethnology; Lipoproteins, HDL - blood; Lipoproteins, LDL - blood; Lipoproteins, LDL - classification; Male; Middle Aged; Multivariate Analysis; Risk Factors; Small dense low-density lipoprotein-cholesterol; Japan

Aim: Small dense low-density lipoprotein (sdLDL) has been suggested to be more atherogenic than large buoyant LDL. High-density lipoprotein (HDL) consists of two major subfractions (HDL2, HDL3), and just as controversy remains regarding which of the two is the more powerful negative risk factor for...