Prevalence and spatial distribution characteristics of human echinococcosis: A county-level modeling study in southern Xinjiang, China

• Published in: Heliyon Vol. 10; no. 7; p. e28812
• Main Authors: Zhang, Yue, Wu, Jun, Adili, Simayi, Wang, Shuo, Zhang, Haiting, Shi, Guangzhong, Zhao, Jiangshan
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 15.04.2024; Elsevier
• Subjects: autocorrelation; China; Echinococcosis; Epidemiologic characteristics; humans; infectious diseases; public health; regression analysis; risk; Southern Xinjiang; Spatial clustering; China; Epidemiologic characteristics; Spatial clustering; Southern Xinjiang; Echinococcosis
• DOI: 10.1016/j.heliyon.2024.e28812
• ISSN: 2405-8440

Human echinococcosis remains an important public health problem. The aim of this study was to analyze the prevalence and spatial distribution characteristics of human echinococcosis cases in southern Xinjiang, China from 2005 to 2021. Human echinococcosis cases were collected from the National Infectious Disease Reporting System. Joinpoint regression analysis was performed to explore the trends. Spatial autocorrelation, hot spot analysis, as well as spatial-temporal clustering analysis were conducted to confirm the distribution and risk factors. A total of 4580 cases were reported in southern Xinjiang during 2005–2021, with a mean annual incidence of 2.56/100,000. Echinococcosis incidence showed an increasing trend from 2005 to 2017 (APC = 17.939, 95%CI: 13.985 to 22.029) and a decreasing trend from 2017 to 2021 (APC = −18.769, 95%CI: 28.157 to −8.154). Echinococcosis cases had a positive spatial autocorrelation in 2005–2021 (Moran's I = 0.19, P < 0.05). The disease hotspots were located in the east and west in these areas, then returned to the east clusters, including Hejing, Heshuo, Wuqia, Atushi, Aheqi, and Yanqi Hui Autonomous County. Meanwhile, spatial-temporal analysis identified the first cluster comprised of five counties (cities): Yanqi Hui Autonomous County, Korla City, Bohu County, Hejing County, and Heshuo County. And secondary clusters 1–3 are predominantly in Wushi County, Aheqi County, Keping County, Atushi City, Wuqia County and Cele County. Our findings suggest that echinococcosis is still an important zoonotic parasitic disease in southern Xinjiang, yet it showed a certain degree of spatial clustering. It is crucial to implement comprehensive prevention and control measures to effectively combat the epidemic of echinococcosis.