Numerical and experimental investigations of pulsatile blood flow pattern through a dysfunctional mechanical heart valve

• Published in: Journal of biomechanics Vol. 43; no. 8; pp. 1565 - 1572
• Main Authors: Smadi, O., Hassan, I., Pibarot, P., Kadem, L.
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Ltd 28.05.2010; Elsevier; Elsevier Limited
• Subjects: Biological and medical sciences; Blood; Blood Flow Velocity; CFD; Computational fluid dynamics; Computer Simulation; Computerized, statistical medical data processing and models in biomedicine; Doppler-echocardiography; Dysfunctional mechanical heart valve; Equipment Failure Analysis; Fluid flow; Heart Valve Prosthesis; Heart valves; Humans; In vitro model; Malfunctions; Medical sciences; Models and simulation; Models, Cardiovascular; Physical Medicine and Rehabilitation; Platelet activation; Prosthesis Design; Prosthesis Failure; Pulsatile Flow; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Surgery of the heart; Turbulence; Turbulent flow; Valves; CFD; In vitro model; Platelet activation; Dysfunctional mechanical heart valve; Doppler-echocardiography; Sonography; Doppler ultrasound study; Echocardiography; Computational fluid dynamics; Mechanical prosthesis; Theoretical study; Experimental study; Heart valve; In vitro; Modeling; Blood flow; Biomechanics; Dysfunction; Surgery; Numerical simulation; Hemodynamics; Simulation model; Biomedical engineering
• ISSN: 0021-9290; 1873-2380; 1873-2380
• DOI: 10.1016/j.jbiomech.2010.01.029

Around 250,000 heart valve replacements are performed every year around the world. Due their higher durability, approximately 2/3 of these replacements use mechanical prosthetic heart valves (mainly bileaflet valves). Although very efficient, these valves can be subject to valve leaflet malfunctions...