The neuropathology of autism: defects of neurogenesis and neuronal migration, and dysplastic changes

• Published in: Acta neuropathologica Vol. 119; no. 6; pp. 755 - 770
• Main Authors: Wegiel, Jerzy, Kuchna, Izabela, Nowicki, Krzysztof, Imaki, Humi, Wegiel, Jarek, Marchi, Elaine, Ma, Shuang Yong, Chauhan, Abha, Chauhan, Ved, Bobrowicz, Teresa Wierzba, de Leon, Mony, Louis, Leslie A. Saint, Cohen, Ira L., London, Eric, Brown, W. Ted, Wisniewski, Thomas
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer-Verlag 01.06.2010; Springer Nature B.V
• Subjects: Adolescent; Adult; Autism; Autistic Disorder - complications; Autistic Disorder - genetics; Autistic Disorder - pathology; Brain - growth & development; Brain - pathology; Case-Control Studies; Cell Movement; Child; Child, Preschool; Cohort Studies; Female; Humans; Male; Medicine; Medicine & Public Health; Middle Aged; Neurogenesis; Neurons - pathology; Neurosciences; Original Paper; Pathology; Young Adult; Autism; Dysplasia; Subependymal nodular dysplasia; Heterotopia; Developmental neuropathology

Autism is characterized by a broad spectrum of clinical manifestations including qualitative impairments in social interactions and communication, and repetitive and stereotyped patterns of behavior. Abnormal acceleration of brain growth in early childhood, signs of slower growth of neurons, and min...