The neuropathology of autism: defects of neurogenesis and neuronal migration, and dysplastic changes
Autism is characterized by a broad spectrum of clinical manifestations including qualitative impairments in social interactions and communication, and repetitive and stereotyped patterns of behavior. Abnormal acceleration of brain growth in early childhood, signs of slower growth of neurons, and min...
Saved in:
| Published in | Acta neuropathologica Vol. 119; no. 6; pp. 755 - 770 |
|---|---|
| Main Authors | , , , , , , , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Berlin/Heidelberg
Springer-Verlag
01.06.2010
Springer Nature B.V |
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | Autism is characterized by a broad spectrum of clinical manifestations including qualitative impairments in social interactions and communication, and repetitive and stereotyped patterns of behavior. Abnormal acceleration of brain growth in early childhood, signs of slower growth of neurons, and minicolumn developmental abnormalities suggest multiregional alterations. The aim of this study was to detect the patterns of focal qualitative developmental defects and to identify brain regions that are prone to developmental alterations in autism. Formalin-fixed brain hemispheres of 13 autistic (4–60 years of age) and 14 age-matched control subjects were embedded in celloidin and cut into 200-μm-thick coronal sections, which were stained with cresyl violet and used for neuropathological evaluation. Thickening of the subependymal cell layer in two brains and subependymal nodular dysplasia in one brain is indicative of active neurogenesis in two autistic children. Subcortical, periventricular, hippocampal and cerebellar heterotopias detected in the brains of four autistic subjects (31%) reflect abnormal neuronal migration. Multifocal cerebral dysplasia resulted in local distortion of the cytoarchitecture of the neocortex in four brains (31%), of the entorhinal cortex in two brains (15%), of the cornu Ammonis in four brains and of the dentate gyrus in two brains. Cerebellar flocculonodular dysplasia detected in six subjects (46%), focal dysplasia in the vermis in one case, and hypoplasia in one subject indicate local failure of cerebellar development in 62% of autistic subjects. Detection of flocculonodular dysplasia in only one control subject and of a broad spectrum of focal qualitative neuropathological developmental changes in 12 of 13 examined brains of autistic subjects (92%) reflects multiregional dysregulation of neurogenesis, neuronal migration and maturation in autism, which may contribute to the heterogeneity of the clinical phenotype. |
|---|---|
| AbstractList | Autism is characterized by a broad spectrum of clinical manifestations including qualitative impairments in social interactions and communication, and repetitive and stereotyped patterns of behavior. Abnormal acceleration of brain growth in early childhood, signs of slower growth of neurons, and minicolumn developmental abnormalities suggest multiregional alterations. The aim of this study was to detect the patterns of focal qualitative developmental defects and to identify brain regions that are prone to developmental alterations in autism. Formalin-fixed brain hemispheres of 13 autistic (4–60 years of age) and 14 age-matched control subjects were embedded in celloidin and cut into 200-μm-thick coronal sections, which were stained with cresyl violet and used for neuropathological evaluation. Thickening of the subependymal cell layer in two brains and subependymal nodular dysplasia in one brain is indicative of active neurogenesis in two autistic children. Subcortical, periventricular, hippocampal and cerebellar heterotopias detected in the brains of four autistic subjects (31%) reflect abnormal neuronal migration. Multifocal cerebral dysplasia resulted in local distortion of the cytoarchitecture of the neocortex in four brains (31%), of the entorhinal cortex in two brains (15%), of the cornu Ammonis in four brains and of the dentate gyrus in two brains. Cerebellar flocculonodular dysplasia detected in six subjects (46%), focal dysplasia in the vermis in one case, and hypoplasia in one subject indicate local failure of cerebellar development in 62% of autistic subjects. Detection of flocculonodular dysplasia in only one control subject and of a broad spectrum of focal qualitative neuropathological developmental changes in 12 of 13 examined brains of autistic subjects (92%) reflects multiregional dysregulation of neurogenesis, neuronal migration and maturation in autism, which may contribute to the heterogeneity of the clinical phenotype. Autism is characterized by a broad spectrum of clinical manifestations including qualitative impairments in social interactions and communication, and repetitive and stereotyped patterns of behavior. Abnormal acceleration of brain growth in early childhood, signs of slower growth of neurons, and minicolumn developmental abnormalities suggest multiregional alterations. The aim of this study was to detect the patterns of focal qualitative developmental defects and to identify brain regions that are prone to developmental alterations in autism. Formalin-fixed brain hemispheres of 13 autistic (4-60 years of age) and 14 age-matched control subjects were embedded in celloidin and cut into 200-mum-thick coronal sections, which were stained with cresyl violet and used for neuropathological evaluation. Thickening of the subependymal cell layer in two brains and subependymal nodular dysplasia in one brain is indicative of active neurogenesis in two autistic children. Subcortical, periventricular, hippocampal and cerebellar heterotopias detected in the brains of four autistic subjects (31%) reflect abnormal neuronal migration. Multifocal cerebral dysplasia resulted in local distortion of the cytoarchitecture of the neocortex in four brains (31%), of the entorhinal cortex in two brains (15%), of the cornu Ammonis in four brains and of the dentate gyrus in two brains. Cerebellar flocculonodular dysplasia detected in six subjects (46%), focal dysplasia in the vermis in one case, and hypoplasia in one subject indicate local failure of cerebellar development in 62% of autistic subjects. Detection of flocculonodular dysplasia in only one control subject and of a broad spectrum of focal qualitative neuropathological developmental changes in 12 of 13 examined brains of autistic subjects (92%) reflects multiregional dysregulation of neurogenesis, neuronal migration and maturation in autism, which may contribute to the heterogeneity of the clinical phenotype.Autism is characterized by a broad spectrum of clinical manifestations including qualitative impairments in social interactions and communication, and repetitive and stereotyped patterns of behavior. Abnormal acceleration of brain growth in early childhood, signs of slower growth of neurons, and minicolumn developmental abnormalities suggest multiregional alterations. The aim of this study was to detect the patterns of focal qualitative developmental defects and to identify brain regions that are prone to developmental alterations in autism. Formalin-fixed brain hemispheres of 13 autistic (4-60 years of age) and 14 age-matched control subjects were embedded in celloidin and cut into 200-mum-thick coronal sections, which were stained with cresyl violet and used for neuropathological evaluation. Thickening of the subependymal cell layer in two brains and subependymal nodular dysplasia in one brain is indicative of active neurogenesis in two autistic children. Subcortical, periventricular, hippocampal and cerebellar heterotopias detected in the brains of four autistic subjects (31%) reflect abnormal neuronal migration. Multifocal cerebral dysplasia resulted in local distortion of the cytoarchitecture of the neocortex in four brains (31%), of the entorhinal cortex in two brains (15%), of the cornu Ammonis in four brains and of the dentate gyrus in two brains. Cerebellar flocculonodular dysplasia detected in six subjects (46%), focal dysplasia in the vermis in one case, and hypoplasia in one subject indicate local failure of cerebellar development in 62% of autistic subjects. Detection of flocculonodular dysplasia in only one control subject and of a broad spectrum of focal qualitative neuropathological developmental changes in 12 of 13 examined brains of autistic subjects (92%) reflects multiregional dysregulation of neurogenesis, neuronal migration and maturation in autism, which may contribute to the heterogeneity of the clinical phenotype. Autism is characterized by a broad spectrum of clinical manifestations including qualitative impairments in social interactions and communication, and repetitive and stereotyped patterns of behavior. Abnormal acceleration of brain growth in early childhood, signs of slower growth of neurons, and minicolumn developmental abnormalities suggest multiregional alterations. The aim of this study was to detect the patterns of focal qualitative developmental defects and to identify brain regions that are prone to developmental alterations in autism. Formalin-fixed brain hemispheres of 13 autistic (4-60 years of age) and 14 age-matched control subjects were embedded in celloidin and cut into 200-μm-thick coronal sections, which were stained with cresyl violet and used for neuropathological evaluation. Thickening of the subependymal cell layer in two brains and subependymal nodular dysplasia in one brain is indicative of active neurogenesis in two autistic children. Subcortical, periventricular, hippocampal and cerebellar heterotopias detected in the brains of four autistic subjects (31%) reflect abnormal neuronal migration. Multifocal cerebral dysplasia resulted in local distortion of the cytoarchitecture of the neocortex in four brains (31%), of the entorhinal cortex in two brains (15%), of the cornu Ammonis in four brains and of the dentate gyrus in two brains. Cerebellar flocculonodular dysplasia detected in six subjects (46%), focal dysplasia in the vermis in one case, and hypoplasia in one subject indicate local failure of cerebellar development in 62% of autistic subjects. Detection of flocculonodular dysplasia in only one control subject and of a broad spectrum of focal qualitative neuropathological developmental changes in 12 of 13 examined brains of autistic subjects (92%) reflects multiregional dysregulation of neurogenesis, neuronal migration and maturation in autism, which may contribute to the heterogeneity of the clinical phenotype.[PUBLICATION ABSTRACT] Autism is characterized by a broad spectrum of clinical manifestations including qualitative impairments in social interactions and communication, and repetitive and stereotyped patterns of behavior. Abnormal acceleration of brain growth in early childhood, signs of slower growth of neurons, and minicolumn developmental abnormalities suggest multiregional alterations. The aim of this study was to detect the patterns of focal qualitative developmental defects and to identify brain regions that are prone to developmental alterations in autism. Formalin-fixed brain hemispheres of 13 autistic (4-60years of age) and 14 age-matched control subjects were embedded in celloidin and cut into 200-km-thick coronal sections, which were stained with cresyl violet and used for neuropathological evaluation. Thickening of the subependymal cell layer in two brains and subependymal nodular dysplasia in one brain is indicative of active neurogenesis in two autistic children. Subcortical, periventricular, hippocampal and cerebellar heterotopias detected in the brains of four autistic subjects (31%) reflect abnormal neuronal migration. Multifocal cerebral dysplasia resulted in local distortion of the cytoarchitecture of the neocortex in four brains (31%), of the entorhinal cortex in two brains (15%), of the cornu Ammonis in four brains and of the dentate gyrus in two brains. Cerebellar flocculonodular dysplasia detected in six subjects (46%), focal dysplasia in the vermis in one case, and hypoplasia in one subject indicate local failure of cerebellar development in 62% of autistic subjects. Detection of flocculonodular dysplasia in only one control subject and of a broad spectrum of focal qualitative neuropathological developmental changes in 12 of 13 examined brains of autistic subjects (92%) reflects multiregional dysregulation of neurogenesis, neuronal migration and maturation in autism, which may contribute to the heterogeneity of the clinical phenotype. Autism is characterized by a broad spectrum of clinical manifestations including qualitative impairments in social interactions and communication, and repetitive and stereotyped patterns of behavior. Abnormal acceleration of brain growth in early childhood, signs of slower growth of neurons, and minicolumn developmental abnormalities suggest multiregional alterations. The aim of this study was to detect the patterns of focal qualitative developmental defects and to identify brain regions that are prone to developmental alterations in autism. Formalin-fixed brain hemispheres of 13 autistic (4-60 years of age) and 14 age-matched control subjects were embedded in celloidin and cut into 200-mum-thick coronal sections, which were stained with cresyl violet and used for neuropathological evaluation. Thickening of the subependymal cell layer in two brains and subependymal nodular dysplasia in one brain is indicative of active neurogenesis in two autistic children. Subcortical, periventricular, hippocampal and cerebellar heterotopias detected in the brains of four autistic subjects (31%) reflect abnormal neuronal migration. Multifocal cerebral dysplasia resulted in local distortion of the cytoarchitecture of the neocortex in four brains (31%), of the entorhinal cortex in two brains (15%), of the cornu Ammonis in four brains and of the dentate gyrus in two brains. Cerebellar flocculonodular dysplasia detected in six subjects (46%), focal dysplasia in the vermis in one case, and hypoplasia in one subject indicate local failure of cerebellar development in 62% of autistic subjects. Detection of flocculonodular dysplasia in only one control subject and of a broad spectrum of focal qualitative neuropathological developmental changes in 12 of 13 examined brains of autistic subjects (92%) reflects multiregional dysregulation of neurogenesis, neuronal migration and maturation in autism, which may contribute to the heterogeneity of the clinical phenotype. |
| Author | Nowicki, Krzysztof Wegiel, Jerzy Imaki, Humi Marchi, Elaine Kuchna, Izabela London, Eric Chauhan, Ved de Leon, Mony Wisniewski, Thomas Louis, Leslie A. Saint Brown, W. Ted Chauhan, Abha Cohen, Ira L. Ma, Shuang Yong Wegiel, Jarek Bobrowicz, Teresa Wierzba |
| Author_xml | – sequence: 1 givenname: Jerzy surname: Wegiel fullname: Wegiel, Jerzy email: jerzy.wegiel@omr.state.ny.us organization: Department of Developmental Neurobiology, NYS Institute for Basic Research in Developmental Disabilities (IBR) – sequence: 2 givenname: Izabela surname: Kuchna fullname: Kuchna, Izabela organization: Department of Developmental Neurobiology, NYS Institute for Basic Research in Developmental Disabilities (IBR) – sequence: 3 givenname: Krzysztof surname: Nowicki fullname: Nowicki, Krzysztof organization: Department of Developmental Neurobiology, NYS Institute for Basic Research in Developmental Disabilities (IBR) – sequence: 4 givenname: Humi surname: Imaki fullname: Imaki, Humi organization: Department of Developmental Neurobiology, NYS Institute for Basic Research in Developmental Disabilities (IBR) – sequence: 5 givenname: Jarek surname: Wegiel fullname: Wegiel, Jarek organization: Department of Developmental Neurobiology, NYS Institute for Basic Research in Developmental Disabilities (IBR) – sequence: 6 givenname: Elaine surname: Marchi fullname: Marchi, Elaine organization: Department of Developmental Neurobiology, NYS Institute for Basic Research in Developmental Disabilities (IBR) – sequence: 7 givenname: Shuang Yong surname: Ma fullname: Ma, Shuang Yong organization: Department of Developmental Neurobiology, NYS Institute for Basic Research in Developmental Disabilities (IBR) – sequence: 8 givenname: Abha surname: Chauhan fullname: Chauhan, Abha organization: Department of Neurochemistry, IBR – sequence: 9 givenname: Ved surname: Chauhan fullname: Chauhan, Ved organization: Department of Neurochemistry, IBR – sequence: 10 givenname: Teresa Wierzba surname: Bobrowicz fullname: Bobrowicz, Teresa Wierzba organization: Department of Neuropathology, Institute of Psychiatry and Neurology – sequence: 11 givenname: Mony surname: de Leon fullname: de Leon, Mony organization: Department of Neurology, New York University School of Medicine, Department of Pathology, New York University School of Medicine, Department of Psychiatry, New York University School of Medicine, Nathan S. Kline Institute for Psychiatric Research – sequence: 12 givenname: Leslie A. Saint surname: Louis fullname: Louis, Leslie A. Saint organization: Department of Neurology, New York University School of Medicine, Department of Pathology, New York University School of Medicine, Department of Psychiatry, New York University School of Medicine, Corinthian Diagnostic Radiology – sequence: 13 givenname: Ira L. surname: Cohen fullname: Cohen, Ira L. organization: Department of Psychology, IBR – sequence: 14 givenname: Eric surname: London fullname: London, Eric organization: Department of Psychology, IBR – sequence: 15 givenname: W. Ted surname: Brown fullname: Brown, W. Ted organization: Department of Human Genetics, IBR – sequence: 16 givenname: Thomas surname: Wisniewski fullname: Wisniewski, Thomas organization: Department of Developmental Neurobiology, NYS Institute for Basic Research in Developmental Disabilities (IBR), Department of Neurology, New York University School of Medicine, Department of Pathology, New York University School of Medicine, Department of Psychiatry, New York University School of Medicine |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/20198484$$D View this record in MEDLINE/PubMed |
| BookMark | eNqFkstu1DAUhi1URKeFB2CDIjZsGji-JyyQUEUBqRKbsrY8tpNxldiDnSDN2-NMWi6VgJXlc77_17mdoZMQg0PoOYbXGEC-yQAMcA0YahCc1-wR2mBGSQ2c0hO0AShZQQk5RWc535YfkYw_QacEcNuwhm2Qvdm5Krg5xb2ednGI_aGKXaXnyefxbWVd58yUl9AR6l1w2edKB7sGgh6q0fdJTz6Gi2PcHvJ-0HnypjI7HXqXn6LHnR6ye3b3nqOvVx9uLj_V118-fr58f10bLsRUG-e4hlYaYI1mHem2LbG2dNcZJ5pOSk1pK23HBTSaCOtoC3JbeEtANs7Qc_Ru9d3P29FZ48KU9KD2yY86HVTUXv2ZCX6n-vhdkUa0wHAxeHVnkOK32eVJjT4bNww6uDhnJZnAnDDG_k9SygnmbVvIlw_I2zinMresCMaNIAwW6MXvlf8s-X5RBZArYFLMOblOGT8dh14a8YPCoJaTUOtJqDI0tZyEWpT4gfLe_F8asmpyYcsG06-a_y76AWaVyY4 |
| CitedBy_id | crossref_primary_10_1007_s11689_011_9084_5 crossref_primary_10_3389_fped_2014_00095 crossref_primary_10_1016_j_braindev_2013_01_003 crossref_primary_10_3389_fpsyt_2017_00126 crossref_primary_10_1172_jci_insight_88609 crossref_primary_10_1016_j_ijdevneu_2018_03_008 crossref_primary_10_1093_jnen_nlx003 crossref_primary_10_15283_ijsc21088 crossref_primary_10_1007_s10803_013_1939_z crossref_primary_10_1016_j_physbeh_2012_04_010 crossref_primary_10_1002_jnr_23759 crossref_primary_10_1186_s13041_015_0164_4 crossref_primary_10_1186_s13229_016_0082_z crossref_primary_10_1002_aur_2597 crossref_primary_10_1371_journal_pone_0073144 crossref_primary_10_1016_j_neuroscience_2016_01_030 crossref_primary_10_1007_s12519_018_0164_4 crossref_primary_10_1177_13623613231154053 crossref_primary_10_1007_s10484_021_09509_z crossref_primary_10_1186_s12859_019_2834_1 crossref_primary_10_1016_j_neuint_2019_104580 crossref_primary_10_1007_s10803_020_04546_9 crossref_primary_10_1016_j_ijdevneu_2013_01_006 crossref_primary_10_1186_s13256_016_1020_6 crossref_primary_10_3389_fncel_2018_00482 crossref_primary_10_1002_aur_2365 crossref_primary_10_2478_s13380_011_0016_3 crossref_primary_10_1038_s41593_021_00967_6 crossref_primary_10_3892_etm_2021_11024 crossref_primary_10_3389_fpsyt_2022_985713 crossref_primary_10_1016_j_neuron_2017_06_048 crossref_primary_10_3389_fpsyt_2019_00647 crossref_primary_10_1002_brb3_483 crossref_primary_10_3389_fchem_2016_00012 crossref_primary_10_1016_j_neulet_2018_06_004 crossref_primary_10_3389_fcell_2021_716300 crossref_primary_10_1007_s00795_017_0161_z crossref_primary_10_1016_j_ydbio_2014_09_009 crossref_primary_10_1016_j_media_2019_101567 crossref_primary_10_1038_nn_2972 crossref_primary_10_1097_WCO_0b013e32835ee64f crossref_primary_10_1038_s12276_024_01284_1 crossref_primary_10_1016_j_neuron_2014_07_016 crossref_primary_10_1016_j_conb_2017_12_005 crossref_primary_10_1038_s41386_023_01659_4 crossref_primary_10_1016_j_neuron_2011_02_018 crossref_primary_10_1016_j_npep_2018_09_003 crossref_primary_10_1093_hmg_ddw077 crossref_primary_10_1002_uog_26187 crossref_primary_10_1016_j_yebeh_2018_03_003 crossref_primary_10_1016_j_bbr_2012_12_062 crossref_primary_10_1111_pcn_12962 crossref_primary_10_1073_pnas_1500968112 crossref_primary_10_1016_S2213_8587_19_30153_6 crossref_primary_10_1038_mp_2017_236 crossref_primary_10_1002_aur_1297 crossref_primary_10_1038_tp_2012_143 crossref_primary_10_1007_s10803_015_2547_x crossref_primary_10_1242_dev_069963 crossref_primary_10_1016_j_brainres_2010_08_067 crossref_primary_10_1016_j_pbb_2013_08_016 crossref_primary_10_1186_s40478_015_0183_5 crossref_primary_10_1016_j_tox_2022_153358 crossref_primary_10_1016_j_neubiorev_2010_12_013 crossref_primary_10_1007_s00429_013_0562_2 crossref_primary_10_1016_j_neuroscience_2017_12_050 crossref_primary_10_1002_aur_2312 crossref_primary_10_1016_j_mcn_2020_103503 crossref_primary_10_1002_dneu_22824 crossref_primary_10_1016_j_neuropharm_2019_107782 crossref_primary_10_1038_s41419_020_03363_3 crossref_primary_10_3389_fncel_2016_00191 crossref_primary_10_1038_s41598_021_86442_5 crossref_primary_10_1080_21541248_2019_1610302 crossref_primary_10_1186_s13229_024_00628_y crossref_primary_10_1093_cercor_bhaa402 crossref_primary_10_1146_annurev_clinpsy_050212_185627 crossref_primary_10_1016_j_neuroscience_2016_10_052 crossref_primary_10_1007_s12311_015_0669_5 crossref_primary_10_1016_j_yebeh_2021_107990 crossref_primary_10_1007_s00429_019_01841_9 crossref_primary_10_1016_j_brainres_2021_147350 crossref_primary_10_1038_s44319_024_00073_1 crossref_primary_10_1016_j_biopsych_2020_03_022 crossref_primary_10_4103_1673_5374_285002 crossref_primary_10_3389_fnins_2022_1023665 crossref_primary_10_1038_ncomms5692 crossref_primary_10_1177_13623613211014408 crossref_primary_10_1016_j_neuroscience_2014_11_033 crossref_primary_10_1176_appi_neuropsych_11110336 crossref_primary_10_1007_s10803_022_05789_4 crossref_primary_10_4103_1673_5374_274345 crossref_primary_10_2174_1570159X22666231003121513 crossref_primary_10_1002_aur_1259 crossref_primary_10_1016_j_neuroscience_2019_05_054 crossref_primary_10_1016_j_nbd_2012_02_016 crossref_primary_10_1093_hmg_ddv138 crossref_primary_10_1155_2013_801517 crossref_primary_10_1016_j_lssr_2022_07_007 crossref_primary_10_1016_j_euroneuro_2019_09_254 crossref_primary_10_3389_fncel_2024_1320784 crossref_primary_10_1002_jnr_22704 crossref_primary_10_1242_dev_202879 crossref_primary_10_1016_j_neuroimage_2014_10_011 crossref_primary_10_1016_j_ntt_2012_08_005 crossref_primary_10_1093_cercor_bhx042 crossref_primary_10_1002_bdr2_2022 crossref_primary_10_1002_hbm_23520 crossref_primary_10_1177_0300985814561270 crossref_primary_10_1007_s12035_015_9351_7 crossref_primary_10_1016_j_spen_2020_100832 crossref_primary_10_1038_s41593_020_0603_0 crossref_primary_10_3390_jcm8122088 crossref_primary_10_3389_fcell_2019_00205 crossref_primary_10_1016_j_npep_2020_102073 crossref_primary_10_1002_ana_23976 crossref_primary_10_1073_pnas_1800184115 crossref_primary_10_1017_S1740925X1200004X crossref_primary_10_1093_brain_awy190 crossref_primary_10_1016_j_neuron_2018_05_039 crossref_primary_10_1542_peds_2019_3447 crossref_primary_10_7554_eLife_91634 crossref_primary_10_1007_s10803_012_1543_7 crossref_primary_10_1111_ppe_12034 crossref_primary_10_1007_s12011_022_03548_1 crossref_primary_10_1186_2045_9912_1_14 crossref_primary_10_2147_NDT_S390053 crossref_primary_10_3389_fpsyt_2015_00121 crossref_primary_10_3390_genes8020048 crossref_primary_10_3892_ijmm_2014_1703 crossref_primary_10_1016_j_brainres_2013_03_037 crossref_primary_10_1002_1873_3468_12626 crossref_primary_10_17116_flebo202418021163 crossref_primary_10_1056_NEJMoa1307491 crossref_primary_10_7554_eLife_82809 crossref_primary_10_1177_0883073811402203 crossref_primary_10_1016_j_rasd_2017_09_003 crossref_primary_10_3389_fnins_2015_00420 crossref_primary_10_1177_0883073813511856 crossref_primary_10_1016_j_stem_2019_12_013 crossref_primary_10_3389_fcell_2022_976549 crossref_primary_10_1002_jdn_10335 crossref_primary_10_1371_journal_pone_0149041 crossref_primary_10_3390_life12071004 crossref_primary_10_3389_fcell_2020_00231 crossref_primary_10_1002_jdn_10213 crossref_primary_10_1093_braincomms_fcae260 crossref_primary_10_3389_fpsyt_2018_00535 crossref_primary_10_3389_fpsyt_2018_00656 crossref_primary_10_1038_s41598_021_89393_z crossref_primary_10_1177_1362361310395956 crossref_primary_10_1371_journal_pone_0164403 crossref_primary_10_1002_emmm_201100157 crossref_primary_10_1016_j_pnpbp_2023_110876 crossref_primary_10_1186_s13148_020_00993_4 crossref_primary_10_1007_s12035_012_8350_1 crossref_primary_10_1093_cercor_bhy185 crossref_primary_10_1007_s00441_017_2718_5 crossref_primary_10_1002_aur_3123 crossref_primary_10_1016_j_biopsych_2023_11_004 crossref_primary_10_1091_mbc_e11_06_0504 crossref_primary_10_1016_j_neuroscience_2015_10_043 crossref_primary_10_1111_ejn_15724 crossref_primary_10_1016_j_mehy_2013_12_018 crossref_primary_10_1139_cjpp_2022_0270 crossref_primary_10_1002_gps_2711 crossref_primary_10_1016_j_spen_2017_10_004 crossref_primary_10_1038_cddis_2014_227 crossref_primary_10_1038_srep12434 crossref_primary_10_3389_fncel_2016_00229 crossref_primary_10_1038_s41598_019_45348_z crossref_primary_10_1016_j_neuropharm_2024_110101 crossref_primary_10_3390_ijms16023095 crossref_primary_10_1016_j_neubiorev_2013_09_010 crossref_primary_10_3389_fpsyt_2018_00751 crossref_primary_10_1371_journal_pone_0035414 crossref_primary_10_3389_fncel_2019_00218 crossref_primary_10_1016_j_biopsych_2017_11_011 crossref_primary_10_1186_s13229_018_0219_3 crossref_primary_10_1007_s10803_011_1259_0 crossref_primary_10_1093_cercor_bhaa011 crossref_primary_10_1016_j_neubiorev_2016_12_037 crossref_primary_10_1038_emm_2016_53 crossref_primary_10_1111_apa_12943 crossref_primary_10_1038_nrn3915 crossref_primary_10_1159_000495660 crossref_primary_10_3389_fnins_2016_00610 crossref_primary_10_1155_2018_3632159 crossref_primary_10_1007_s10803_022_05626_8 crossref_primary_10_1177_0883073812452917 crossref_primary_10_1016_j_nicl_2015_10_017 crossref_primary_10_3390_ijms252312598 crossref_primary_10_1126_sciadv_abk1238 crossref_primary_10_1097_NEN_0000000000000108 crossref_primary_10_1111_desc_12424 crossref_primary_10_3390_ijms25021086 crossref_primary_10_2478_v10215_011_0024_4 crossref_primary_10_3389_fncel_2017_00359 crossref_primary_10_3233_BPL_180064 crossref_primary_10_3389_fncel_2014_00397 crossref_primary_10_4161_sgtp_26602 crossref_primary_10_1093_toxsci_kfz136 crossref_primary_10_1016_j_celrep_2019_04_081 crossref_primary_10_1038_s41598_023_46206_9 crossref_primary_10_1016_j_jchemneu_2022_102219 crossref_primary_10_3389_fnins_2023_1172779 crossref_primary_10_1002_dneu_22335 crossref_primary_10_1016_j_brainres_2010_09_101 crossref_primary_10_1016_j_braindev_2012_03_015 crossref_primary_10_3389_fncel_2014_00305 crossref_primary_10_1073_pnas_2120079119 crossref_primary_10_1002_jbio_201600322 crossref_primary_10_1016_j_yebeh_2015_02_017 crossref_primary_10_1155_2014_491316 crossref_primary_10_1007_s40572_017_0135_2 crossref_primary_10_3390_jpm10040260 crossref_primary_10_1016_j_neulet_2017_09_047 crossref_primary_10_1093_bioinformatics_btz128 crossref_primary_10_3389_fpsyt_2023_1162179 crossref_primary_10_1038_mp_2012_20 crossref_primary_10_7863_ultra_33_6_1065 crossref_primary_10_1002_aur_1837 crossref_primary_10_1007_s13238_016_0272_7 crossref_primary_10_1007_s12264_024_01241_y crossref_primary_10_1016_j_brainres_2010_10_015 crossref_primary_10_1007_s12035_022_02936_x crossref_primary_10_2174_1570159X21666221220155455 crossref_primary_10_1093_cercor_bhu080 crossref_primary_10_1186_s13256_021_03064_1 crossref_primary_10_1038_s41380_018_0056_y crossref_primary_10_1186_s40478_018_0645_7 crossref_primary_10_7554_eLife_91634_3 crossref_primary_10_1007_s11910_011_0195_x crossref_primary_10_1007_s12640_022_00574_8 crossref_primary_10_1093_cercor_bhx229 crossref_primary_10_12677_ve_2025_142096 crossref_primary_10_1016_j_semcdb_2017_05_020 crossref_primary_10_1093_aje_kwaa171 crossref_primary_10_3390_cells9112500 crossref_primary_10_1016_j_ijdevneu_2018_07_001 crossref_primary_10_1016_j_stemcr_2022_04_019 crossref_primary_10_1186_2040_2392_2_7 crossref_primary_10_1002_dneu_22127 crossref_primary_10_1016_j_nbd_2024_106558 crossref_primary_10_1093_hmg_ddv301 crossref_primary_10_1097_NEN_0b013e318251f537 crossref_primary_10_1097_YCO_0b013e328345927e crossref_primary_10_3389_fendo_2014_00146 crossref_primary_10_1111_ejn_15420 crossref_primary_10_1016_j_ajpath_2024_02_014 crossref_primary_10_7554_eLife_06085 crossref_primary_10_1523_JNEUROSCI_5449_13_2014 crossref_primary_10_1002_jdn_10056 crossref_primary_10_1097_01_NPR_0000660352_52766_72 crossref_primary_10_51847_DysH69LijA crossref_primary_10_3389_fcell_2022_769853 crossref_primary_10_1016_j_bbr_2011_11_004 crossref_primary_10_1016_j_yebeh_2019_01_011 crossref_primary_10_1016_j_bbr_2012_07_021 crossref_primary_10_1093_cercor_bhw049 crossref_primary_10_1371_journal_pone_0081255 crossref_primary_10_1002_cne_23707 crossref_primary_10_1111_nan_12227 crossref_primary_10_1038_tp_2017_144 crossref_primary_10_1016_j_jchemneu_2011_05_004 crossref_primary_10_1186_2040_2392_2_1 crossref_primary_10_1038_nature09146 crossref_primary_10_1186_2040_2392_2_2 crossref_primary_10_3389_fneur_2024_1221193 crossref_primary_10_3389_fnint_2021_743561 crossref_primary_10_1016_j_brainres_2018_02_041 crossref_primary_10_1038_s41418_019_0314_9 crossref_primary_10_3402_mehd_v23i0_19260 crossref_primary_10_1186_s12974_016_0575_x crossref_primary_10_15252_embr_201642416 crossref_primary_10_1124_dmd_115_063826 crossref_primary_10_1080_02739615_2014_979921 crossref_primary_10_1212_WNL_0b013e3182a9f482 crossref_primary_10_1016_j_neuron_2021_12_035 crossref_primary_10_1093_ije_dyt282 crossref_primary_10_3390_pathogens7030070 crossref_primary_10_1002_jnr_24194 crossref_primary_10_1016_j_psc_2020_02_004 crossref_primary_10_1111_ejn_15454 crossref_primary_10_1515_revneuro_2019_0014 crossref_primary_10_2147_IJN_S459511 crossref_primary_10_1038_s41598_024_53614_y crossref_primary_10_3390_ijms18081627 crossref_primary_10_1186_2040_2392_4_14 crossref_primary_10_1111_j_1471_4159_2011_07189_x crossref_primary_10_1007_s00401_017_1736_4 crossref_primary_10_1093_cercor_bhy112 crossref_primary_10_1016_j_bbrc_2024_150780 crossref_primary_10_3390_ncrna7020036 crossref_primary_10_1093_cercor_bhx143 crossref_primary_10_3390_ijms18030659 crossref_primary_10_1016_j_jneumeth_2018_09_028 crossref_primary_10_1186_s12915_017_0387_1 crossref_primary_10_1111_apha_13613 crossref_primary_10_1159_000530898 crossref_primary_10_3389_fpsyt_2024_1364858 crossref_primary_10_1002_ajmg_c_31946 crossref_primary_10_1523_ENEURO_0246_23_2024 crossref_primary_10_3390_brainsci10120951 crossref_primary_10_1093_cercor_bhaf041 crossref_primary_10_1007_s12311_013_0475_x crossref_primary_10_1242_dmm_039180 crossref_primary_10_3390_biology12101344 crossref_primary_10_1016_j_ibneur_2021_07_003 crossref_primary_10_1186_2040_2392_5_43 crossref_primary_10_3390_brainsci14050454 crossref_primary_10_1016_j_brainres_2018_12_011 crossref_primary_10_1177_1362361314522352 crossref_primary_10_3389_fnins_2022_854422 crossref_primary_10_1007_s11356_022_19865_w crossref_primary_10_1007_s10792_020_01497_z crossref_primary_10_1371_journal_pone_0192925 crossref_primary_10_3390_ijms221910757 crossref_primary_10_3389_fncel_2020_611379 crossref_primary_10_3390_ijerph18189784 crossref_primary_10_1530_EJE_16_0354 crossref_primary_10_1016_j_celrep_2016_04_090 crossref_primary_10_1016_j_tins_2020_03_005 crossref_primary_10_3390_molecules27030889 crossref_primary_10_1016_j_rasd_2024_102410 crossref_primary_10_1111_jnc_13403 crossref_primary_10_1289_ehp_1104553 crossref_primary_10_3390_jdb6040029 crossref_primary_10_3389_fcell_2021_630161 crossref_primary_10_1016_j_neuroscience_2016_02_021 crossref_primary_10_32725_jab_2021_009 crossref_primary_10_1093_hmg_ddz196 crossref_primary_10_1186_1478_811X_12_19 crossref_primary_10_3389_fpsyt_2023_1096769 crossref_primary_10_1038_s41380_024_02441_8 crossref_primary_10_1016_j_pnpbp_2018_12_015 crossref_primary_10_1111_dgd_12280 crossref_primary_10_1016_j_neuroscience_2013_05_042 crossref_primary_10_1021_acschemneuro_3c00738 crossref_primary_10_1016_j_neuropharm_2012_05_042 crossref_primary_10_1016_j_ydbio_2015_02_021 crossref_primary_10_1111_cen_13550 crossref_primary_10_3390_cimb45050274 crossref_primary_10_1186_2051_5960_1_67 crossref_primary_10_1016_j_neuroscience_2018_06_032 crossref_primary_10_1007_s00401_012_0976_6 crossref_primary_10_1186_s13287_019_1267_0 crossref_primary_10_1002_aur_173 crossref_primary_10_1038_s41467_017_01046_w crossref_primary_10_1186_2040_2392_5_17 crossref_primary_10_5858_arpa_2020_0164_RA crossref_primary_10_1007_s10803_015_2672_6 crossref_primary_10_3389_fnana_2016_00002 crossref_primary_10_1038_mp_2015_64 crossref_primary_10_1186_s13229_022_00508_3 crossref_primary_10_3390_cells8080905 crossref_primary_10_1186_2051_5960_2_28 crossref_primary_10_1016_j_yebeh_2013_03_012 crossref_primary_10_1007_s00213_020_05634_5 crossref_primary_10_1016_j_bbi_2011_05_007 crossref_primary_10_4236_ojog_2016_63019 crossref_primary_10_1016_j_etap_2016_08_013 crossref_primary_10_1017_S0954579418000342 crossref_primary_10_1186_s40478_014_0141_7 crossref_primary_10_3390_biology13080606 crossref_primary_10_1186_s13229_024_00611_7 crossref_primary_10_1002_dneu_22549 crossref_primary_10_3389_fncir_2021_676891 crossref_primary_10_1016_j_bbr_2014_12_046 crossref_primary_10_1093_hmg_ddq432 crossref_primary_10_1016_j_neuroimage_2018_05_049 crossref_primary_10_1093_jnen_nlaa095 crossref_primary_10_9758_cpn_2021_19_1_84 crossref_primary_10_1371_journal_pone_0171968 crossref_primary_10_7556_jaoa_2019_007 crossref_primary_10_1007_s11689_011_9083_6 crossref_primary_10_3389_fnana_2016_00107 crossref_primary_10_1016_j_heares_2020_107974 crossref_primary_10_1186_s40478_015_0241_z crossref_primary_10_1016_j_neuroscience_2020_08_028 crossref_primary_10_1016_j_biopsych_2015_06_029 crossref_primary_10_15252_embj_201695734 crossref_primary_10_3389_fgene_2019_00907 crossref_primary_10_1016_j_mehy_2014_04_014 crossref_primary_10_1002_dvdy_100 crossref_primary_10_1007_s00401_018_1904_1 crossref_primary_10_3389_fnint_2021_748977 crossref_primary_10_1093_brain_awad060 crossref_primary_10_1038_s41598_025_86392_2 crossref_primary_10_1002_uog_27473 crossref_primary_10_1080_14728222_2022_2100252 crossref_primary_10_1002_ar_21243 crossref_primary_10_1016_j_bbr_2021_113466 crossref_primary_10_1146_annurev_pathol_012414_040405 crossref_primary_10_1002_hbm_25237 crossref_primary_10_1002_aur_1530 crossref_primary_10_1016_j_jbc_2021_100986 |
| Cites_doi | 10.1212/WNL.35.6.866 10.1371/journal.pone.0004415 10.1056/NEJM198805263182102 10.1001/archneur.1980.00500570052008 10.1002/ana.10579 10.1016/j.ridd.2004.05.003 10.1097/00005072-199403000-00001 10.1007/s00401-006-0085-5 10.1212/WNL.53.7.1384 10.1385/NMM:8:4:531 10.1016/S0006-3223(00)00988-4 10.1007/s002340100588 10.1038/nature08490 10.1037/0894-4105.13.4.564 10.1002/mrdd.20141 10.1177/088307389300800207 10.1016/S0006-3223(00)00228-6 10.1111/j.1469-8749.1968.tb02951.x 10.1038/3305 10.1007/s00401-009-0568-2 10.1055/s-2008-1071280 10.1038/nrn2332 10.1007/s004010050660 10.1016/j.neuroscience.2004.12.051 10.1016/j.ydbio.2007.10.024 10.1212/WNL.58.3.428 10.1212/WNL.39.3.349 10.1016/0092-8674(92)90222-X 10.1016/S0893-133X(01)00358-X 10.1093/brain/awf175 10.1016/S0092-8674(00)80899-5 10.1007/s00401-001-0470-z 10.1016/S0278-5846(99)00020-2 10.1001/archneur.1987.00520150073028 10.1016/0303-8467(95)00059-S 10.1016/S0006-3223(99)00250-4 10.1006/geno.1993.1354 10.1001/archneur.1989.00520420111032 10.1017/S0033291700033821 10.1001/archpsyc.57.11.1061 10.3844/ajbbsp.2008.130.145 10.1111/j.1750-3639.2002.tb00437.x 10.1002/ajmg.a.30590 10.1002/(SICI)1096-9861(19960624)370:2<247::AID-CNE8>3.0.CO;2-2 10.1111/j.1469-7610.1994.tb01164.x 10.1007/s004010050587 10.1523/JNEUROSCI.1610-06.2006 10.1016/S0896-6273(00)80651-0 10.1111/j.1440-1819.1998.tb03226.x 10.1007/BF02178163 10.1523/JNEUROSCI.19-13-05632.1999 10.1016/S1474-4422(02)00160-6 10.1111/j.1469-8749.1996.tb15081.x 10.1016/j.biopsych.2005.03.026 10.1146/annurev.ne.11.030188.000333 10.1017/S031716710002610X 10.1101/lm.47202 10.1002/jnr.21520 10.1523/JNEUROSCI.20-24-09104.2000 10.1097/00005072-199807000-00001 10.1093/epirev/mxf010 10.1016/j.biopsych.2006.03.071 10.1093/brain/121.5.889 10.1016/S0006-3223(00)01008-8 10.1093/hmg/7.7.1063 10.1016/j.biopsych.2005.03.040 10.1038/nn1770 10.1016/j.pathophys.2006.05.007 10.1016/S0896-6273(00)80778-3 10.1007/s00439-009-0702-1 10.1023/A:1005592401947 10.1002/cne.1180 10.1212/WNL.49.2.546 10.1097/00001756-200110290-00014 10.1016/S0891-0618(00)00067-3 10.1136/jmg.2007.055137 10.1093/oxfordjournals.hmg.a018911 10.1023/A:1013234708757 10.1046/j.1471-4159.2000.0751729.x 10.1212/01.WNL.0000158653.81008.49 10.1093/brain/awh287 10.1016/S0014-2999(00)00904-3 10.1523/JNEUROSCI.10-08-02735.1990 10.1002/ana.20234 10.1002/ana.20211 10.1016/S0926-6410(99)00006-3 10.1006/nimg.1999.0459 10.1093/brain/awg110 10.1016/S0893-133X(99)00012-3 10.1016/j.biopsych.2006.09.040 10.1093/brain/118.5.1273 10.1016/S0028-3932(96)00119-4 10.1176/ajp.143.7.862 10.1542/peds.88.6.1211 10.1007/s00401-006-0176-3 10.1093/brain/awn033 10.1023/A:1007072105919 10.1016/S0140-6736(05)74869-8 10.1016/0006-3223(92)90189-7 10.1016/j.ajhg.2007.12.009 10.1111/j.1528-1157.1985.tb05665.x 10.1177/08830738060210062201 10.1093/oso/9780195122107.003.0008 10.1038/ng1985 |
| ContentType | Journal Article |
| Copyright | The Author(s) 2010 Springer-Verlag 2010 |
| Copyright_xml | – notice: The Author(s) 2010 – notice: Springer-Verlag 2010 |
| DBID | C6C AAYXX CITATION CGR CUY CVF ECM EIF NPM 3V. 7TK 7U9 7X7 7XB 88E 88G 8AO 8FI 8FJ 8FK ABUWG AFKRA AZQEC BENPR CCPQU DWQXO FYUFA GHDGH GNUQQ H94 K9. M0S M1P M2M PHGZM PHGZT PJZUB PKEHL PPXIY PQEST PQQKQ PQUKI PRINS PSYQQ Q9U 7X8 5PM |
| DOI | 10.1007/s00401-010-0655-4 |
| DatabaseName | Springer Nature OA Free Journals CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed ProQuest Central (Corporate) Neurosciences Abstracts Virology and AIDS Abstracts Health & Medical Collection ProQuest Central (purchase pre-March 2016) Medical Database (Alumni Edition) Psychology Database (Alumni) ProQuest Pharma Collection Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) ProQuest Central (Alumni) ProQuest Central UK/Ireland ProQuest Central Essentials ProQuest Central ProQuest One Community College ProQuest Central Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Central Student AIDS and Cancer Research Abstracts ProQuest Health & Medical Complete (Alumni) ProQuest Health & Medical Collection Proquest Medical Database Psychology Database ProQuest Central Premium ProQuest One Academic ProQuest Health & Medical Research Collection ProQuest One Academic Middle East (New) ProQuest One Health & Nursing ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Academic ProQuest One Academic UKI Edition ProQuest Central China ProQuest One Psychology ProQuest Central Basic MEDLINE - Academic PubMed Central (Full Participant titles) |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) ProQuest One Psychology ProQuest Central Student ProQuest One Academic Middle East (New) ProQuest Central Essentials ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) ProQuest One Community College ProQuest One Health & Nursing ProQuest Pharma Collection ProQuest Central China ProQuest Central ProQuest Health & Medical Research Collection Health Research Premium Collection Health and Medicine Complete (Alumni Edition) ProQuest Central Korea Health & Medical Research Collection AIDS and Cancer Research Abstracts ProQuest Central (New) ProQuest Medical Library (Alumni) Virology and AIDS Abstracts ProQuest Central Basic ProQuest One Academic Eastern Edition ProQuest Hospital Collection Health Research Premium Collection (Alumni) ProQuest Psychology Journals (Alumni) Neurosciences Abstracts ProQuest Hospital Collection (Alumni) ProQuest Health & Medical Complete ProQuest Medical Library ProQuest Psychology Journals ProQuest One Academic UKI Edition ProQuest One Academic ProQuest One Academic (New) ProQuest Central (Alumni) MEDLINE - Academic |
| DatabaseTitleList | MEDLINE - Academic ProQuest One Psychology Neurosciences Abstracts MEDLINE |
| Database_xml | – sequence: 1 dbid: C6C name: Springer Nature OA Free Journals url: http://www.springeropen.com/ sourceTypes: Publisher – sequence: 2 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 3 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database – sequence: 4 dbid: BENPR name: ProQuest Central url: https://www.proquest.com/central sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 1432-0533 |
| EndPage | 770 |
| ExternalDocumentID | PMC2869041 2028644371 20198484 10_1007_s00401_010_0655_4 |
| Genre | Research Support, U.S. Gov't, Non-P.H.S Research Support, Non-U.S. Gov't Journal Article Research Support, N.I.H., Extramural |
| GrantInformation_xml | – fundername: NICHD NIH HHS grantid: R01 HD043960 – fundername: NICHD NIH HHS grantid: R01 HD43960 – fundername: NIMH NIH HHS grantid: R24-MH 068855 – fundername: NIMH NIH HHS grantid: R24 MH068855 – fundername: NIA NIH HHS grantid: P30 AG008051 |
| GroupedDBID | --- -53 -5E -5G -BR -EM -Y2 -~C .55 .86 .GJ .VR 06C 06D 0R~ 0VY 199 1N0 1SB 2.D 203 23M 28- 29~ 2J2 2JN 2JY 2KG 2KM 2LR 2P1 2VQ 2~H 30V 36B 3O- 3V. 4.4 406 408 409 40D 40E 53G 5GY 5QI 5RE 5VS 67Z 6NX 78A 7X7 88E 8AO 8FI 8FJ 8TC 8UJ 95- 95. 95~ 96X AAAVM AABHQ AACDK AAHNG AAIAL AAJBT AAJKR AANXM AANZL AARHV AARTL AASML AATNV AATVU AAUYE AAWCG AAYIU AAYQN AAYTO AAYZH ABAKF ABBBX ABBXA ABDZT ABECU ABFTV ABHLI ABHQN ABIPD ABIVO ABJNI ABJOX ABKCH ABKTR ABLJU ABMNI ABMQK ABNWP ABPLI ABQBU ABQSL ABSXP ABTEG ABTKH ABTMW ABULA ABUWG ABUWZ ABWNU ABXPI ACAOD ACBXY ACDTI ACGFS ACHSB ACHVE ACHXU ACKNC ACMDZ ACMLO ACOKC ACOMO ACPIV ACPRK ACUDM ACZOJ ADBBV ADHHG ADHIR ADIMF ADINQ ADJJI ADKNI ADKPE ADRFC ADTPH ADURQ ADYFF ADZKW AEBTG AEFIE AEFQL AEGAL AEGNC AEJHL AEJRE AEKMD AEMSY AENEX AEOHA AEPYU AESKC AETLH AEVLU AEXYK AFBBN AFDYV AFEXP AFFNX AFKRA AFLOW AFQWF AFWTZ AFZKB AGAYW AGDGC AGGDS AGJBK AGMZJ AGQEE AGQMX AGRTI AGWIL AGWZB AGYKE AHAVH AHBYD AHIZS AHKAY AHMBA AHSBF AHYZX AIAKS AIGIU AIIXL AILAN AITGF AJBLW AJRNO AJZVZ AKMHD ALIPV ALMA_UNASSIGNED_HOLDINGS ALWAN AMKLP AMXSW AMYLF AMYQR AOCGG ARMRJ ASPBG AVWKF AXYYD AZFZN AZQEC B-. BA0 BBWZM BDATZ BENPR BGNMA BPHCQ BSONS BVXVI C6C CAG CCPQU COF CS3 CSCUP DDRTE DL5 DNIVK DPUIP DWQXO EBLON EBS EIOEI EJD EMOBN EN4 ESBYG F5P FEDTE FERAY FFXSO FIGPU FINBP FNLPD FRRFC FSGXE FWDCC FYUFA G-Y G-Z GGCAI GGRSB GJIRD GNUQQ GNWQR GQ6 GQ7 GQ8 GRRUI GXS H13 HF~ HG5 HG6 HMCUK HMJXF HQYDN HRMNR HVGLF HZ~ I09 IAO IHE IHR IJ- IKXTQ IMOTQ INH INR IPY ITC ITM IWAJR IXC IZIGR IZQ I~X I~Z J-C J0Z JBSCW JCJTX JZLTJ KDC KOV KOW KPH L7B LAS LLZTM M1P M2M M4Y MA- N2Q NB0 NDZJH NPVJJ NQJWS NU0 O9- O93 O9G O9I O9J OAM OVD P19 P2P P9S PF0 PQQKQ PROAC PSQYO PSYQQ PT4 PT5 Q2X QOK QOR QOS R4E R89 R9I RHV RIG RNI ROL RPX RRX RSV RZK S16 S1Z S26 S27 S28 S37 S3B SAP SCLPG SDE SDH SDM SHX SISQX SJYHP SMD SNE SNPRN SNX SOHCF SOJ SPISZ SRMVM SSLCW SSXJD STPWE SZ9 SZN T13 T16 TEORI TSG TSK TSV TT1 TUC U2A U9L UG4 UKHRP UOJIU UTJUX UZXMN VC2 VFIZW W23 W48 WH7 WJK WK8 X7M YLTOR Z45 Z7U Z7V Z81 Z82 Z83 Z87 Z8O Z8P Z8U Z8V Z8W Z91 ZGI ZOVNA ~EX AAPKM AAYXX ABBRH ABDBE ABFSG ACSTC ADHKG AEZWR AFDZB AFHIU AFOHR AGQPQ AHPBZ AHWEU AIXLP ATHPR AYFIA CITATION PHGZM PHGZT ABRTQ CGR CUY CVF ECM EIF NPM PJZUB PPXIY 7TK 7U9 7XB 8FK H94 K9. PKEHL PQEST PQUKI PRINS Q9U 7X8 5PM |
| ID | FETCH-LOGICAL-c566t-cee5a097c048a4f2fb92dd010fce68f77a3397df5608a26de3907b97cd2078ec3 |
| IEDL.DBID | U2A |
| ISSN | 0001-6322 1432-0533 |
| IngestDate | Thu Aug 21 13:52:24 EDT 2025 Fri Jul 11 03:44:45 EDT 2025 Fri Jul 11 03:28:25 EDT 2025 Sat Aug 23 12:55:59 EDT 2025 Mon Jul 21 06:03:44 EDT 2025 Tue Jul 01 03:38:05 EDT 2025 Thu Apr 24 23:10:27 EDT 2025 Fri Feb 21 02:35:55 EST 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 6 |
| Keywords | Autism Dysplasia Subependymal nodular dysplasia Heterotopia Developmental neuropathology |
| Language | English |
| License | This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c566t-cee5a097c048a4f2fb92dd010fce68f77a3397df5608a26de3907b97cd2078ec3 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23 |
| OpenAccessLink | https://link.springer.com/10.1007/s00401-010-0655-4 |
| PMID | 20198484 |
| PQID | 211862409 |
| PQPubID | 49178 |
| PageCount | 16 |
| ParticipantIDs | pubmedcentral_primary_oai_pubmedcentral_nih_gov_2869041 proquest_miscellaneous_746152444 proquest_miscellaneous_733521599 proquest_journals_211862409 pubmed_primary_20198484 crossref_citationtrail_10_1007_s00401_010_0655_4 crossref_primary_10_1007_s00401_010_0655_4 springer_journals_10_1007_s00401_010_0655_4 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2010-06-01 |
| PublicationDateYYYYMMDD | 2010-06-01 |
| PublicationDate_xml | – month: 06 year: 2010 text: 2010-06-01 day: 01 |
| PublicationDecade | 2010 |
| PublicationPlace | Berlin/Heidelberg |
| PublicationPlace_xml | – name: Berlin/Heidelberg – name: Germany – name: Heidelberg |
| PublicationTitle | Acta neuropathologica |
| PublicationTitleAbbrev | Acta Neuropathol |
| PublicationTitleAlternate | Acta Neuropathol |
| PublicationYear | 2010 |
| Publisher | Springer-Verlag Springer Nature B.V |
| Publisher_xml | – name: Springer-Verlag – name: Springer Nature B.V |
| References | KaplanMPChinSSFliegnerKHLiemRKAlpha-internexin, a novel neuronal intermediate filament protein, precedes the low molecular weight neurofilament protein (NF-L) in the developing rat brainJ Neurosci199010273527481:CAS:528:DyaK3cXmtVyrsb8%3D2201753 MarshallCRNoorAVincentJBStructural variation of chromosomes in autism spectrum disorderAm J Human Gen2008824774881:CAS:528:DC%2BD1cXit1Sisrs%3D10.1016/j.ajhg.2007.12.009 BruceSNybergFMelénEThe protective effect of farm animal exposure on childhood allergy is modified by NPSR1 polymorphismsJ Med Genet2009461591671:CAS:528:DC%2BD1MXktlKktb4%3D1828542810.1136/jmg.2007.055137 KremerSDe SaintMAMinottiLFocal cortical dysplasia possibly related to a probable prenatal ischemic injuryJ Neuroradiol2002292002031:STN:280:DC%2BD38novVGnsw%3D%3D12447145 YipJSoghomonianJJBlattGJDecreased GAD67 mRNA levels in cerebellar Purkinje cells in autism: pathophysiological implicationsActa Neuropathol20071135595681:CAS:528:DC%2BD2sXks1ygtL0%3D1723551510.1007/s00401-006-0176-3 RorkeLBFogelsonMHRiggsHECerebellar heterotopia in infancyDev Med Child Neurol1968106446501:STN:280:DyaF1M7gsVyjtw%3D%3D570828510.1111/j.1469-8749.1968.tb02951.x ChangBSWalshCARungeMSPattersonCThe genetic basis of human cerebral cortical malformationsPrinciples of molecular medicine2009Totowa, NJHuman Press Inc10731079 SchmahmannJDDoyonJMcDonaldDThree-dimensional MRI atlas of the human cerebellum in proportional stereotaxic spaceNeuroimage1999102332601:STN:280:DyaK1MzptVSlsw%3D%3D1045894010.1006/nimg.1999.0459 HashimotoTTayamaMMoriKFujinoKMiyazakiMKurodaYMagnetic resonance imaging in autism: preliminary reportNeuropediatrics1989201421461:STN:280:DyaL1MzosFSqsQ%3D%3D277974210.1055/s-2008-1071280 EnglundCKowalczykTDazaRAMUnipolar brush cells of the cerebellum are produced in the rhombic lip and migrate through developing white matterJ Neurosci200626918491951:CAS:528:DC%2BD28XpvFWqtb4%3D1695707510.1523/JNEUROSCI.1610-06.2006 FatemiSHStaryJMHalthARRealmutoGRDysregulation of reelin and Bcl-2 proteins in autistic cerebellumJ Autism Dev Disord2001315295351:STN:280:DC%2BD38%2Fos1yjtA%3D%3D1181426210.1023/A:1013234708757 CaspiMAtlasRKantorASapirTReinerOInteraction between LIS1 and doublecortin, two lissencephaly gene productsHum Mol Genet20009220522131:CAS:528:DC%2BD3cXnt1ynt7c%3D11001923 FoxJWLampertiEDEksiogluYZMutations in filamin 1 prevent migration of cerebral cortical neurons in human periventricular heterotopiaNeuron199821131513251:CAS:528:DyaK1MXntV2lug%3D%3D988372510.1016/S0896-6273(00)80651-0 RitvoERFreemanBJScheibelABLower Purkinje cell counts in the cerebella of four autistic subjects: initial findings of the UCLA-NSAC Autopsy Research ReportAm J Psychiatry19861438628661:STN:280:DyaL283jvFOktw%3D%3D3717426 HappeFRonaldAPlominRTime to give up on a single explanation for autismNat Neurosci20069121812201:CAS:528:DC%2BD28XhtVSgu7bF1700134010.1038/nn1770 TuchmanRFRapinIShinnarSAutistic and dysphasic children. I. Clinical characteristicsPediatrics199188121112181:STN:280:DyaK38%2Fms1Ciuw%3D%3D1956739 BaileyARGiuntaBNObregonDPeripheral biomarkers in autism: secreted amyloid precursor protein-alpha as a probable key player in early diagnosisInt J Clin Exp Med2008133834419079679 des PortesVFrancisFPinardJMDoublecortin is the major gene causing X-linked subcortical laminar heterotopia (SCLH)Hum Mol Genet19987106310701:CAS:528:DyaK1cXktlKrs7g%3D961816210.1093/hmg/7.7.1063 HeinsenHArzbergerTSchmitzCCelloidin mounting (embedding without infiltration)—a new, simple and reliable method for producing serial sections of high thickness through complete human brains and its application to stereological and immunohistochemical investigationsJ Chem Neuroanat20002049591:STN:280:DC%2BD3M%2FotFShug%3D%3D1107434310.1016/S0891-0618(00)00067-3 Marin-PadillaMParisiJEArmstrongDLSargentSKKaplanJAShaken infant syndrome: developmental neuropathology, progressive cortical dysplasia, and epilepsyActa Neuropathol20021033213321190475110.1007/s00401-001-0470-z GabrielsRLCuccaroMLHillDEIversBJGoldsonERepetitive behaviors in autism: relationships with associated clinical featuresRes Dev Disabil2005261691811559024710.1016/j.ridd.2004.05.003 CrinoPBMiyataHVintersHVNeurodevelopmental disorders as a cause of seizures: neuropathologic, genetic, and mechanistic considerationsBrain Pathol2002122122331:CAS:528:DC%2BD38XlvVSjtLk%3D1195837610.1111/j.1750-3639.2002.tb00437.x HonerWGBassettASFalkaiPBeachTGLapointeJSA case study of temporal lobe development in familial schizophreniaPsychol Med1996261911951:STN:280:DyaK283gs1OhtQ%3D%3D864375810.1017/S0033291700033821 GuidottiAAutaJDavisJMDecrease in reelin and glutamic acid decarboxylase67 (GAD67) expression in schizophrenia and bipolar disorder: a postmortem brain studyArch Gen Psychiatry200057106110691:CAS:528:DC%2BD3cXot1WnsL0%3D1107487210.1001/archpsyc.57.11.1061 RodierPMIngramJLTisdaleBNelsonSRomanoJEmbryological origin of autism: developmental abnormalities of the cranial nerve nucleiJ Comp Neurol19963702472611:STN:280:DyaK28vgsVGmsw%3D%3D880873310.1002/(SICI)1096-9861(19960624)370:2<247::AID-CNE8>3.0.CO;2-2 MiyataHChiangACVintersHInsulin signaling pathways in cortical dysplasia and TSC-tubers: tissue microarray analysisAnn Neurol2004565105191:CAS:528:DC%2BD2cXps1Kit74%3D1545539810.1002/ana.20234 HerbertMRZieglerDADeutschCKDissociations of cerebral cortex, subcortical and cerebral white matter volumes in autistic boysBrain2003126118211921:STN:280:DC%2BD3s3gvFyquw%3D%3D1269005710.1093/brain/awg110 ItoMControl of mental activities by internal models in the cerebellumNat Rev Neurosci200893043131:CAS:528:DC%2BD1cXjsFCks70%3D1831972710.1038/nrn2332 VoelbelGTBatesMEBuckmanJFPandinaGHendrenRLCaudate nucleus volume and cognitive performance: are they related in childhood psychopathology?Biol Psychiatry2006609429501695021210.1016/j.biopsych.2006.03.071 YipJJSoghomonianJBlattGJIncreased GAD67 mRNA expression in cerebellar interneurons in autism: implications for Purkinje cell dysfunctionJ Neurosci Res2008865255301:CAS:528:DC%2BD1cXhvF2qsbo%3D1791874210.1002/jnr.21520 MatusAMicrotubule-associated proteins: their potential role in determining neuronal morphologyAnn Rev Neurosci19881129441:CAS:528:DyaL1cXhvVahtL4%3D328444410.1146/annurev.ne.11.030188.000333 MarcotteLCrinoPBThe neurobiology of the tuberous sclerosis complexNeuromol Med200685315461:CAS:528:DC%2BD28XhtFCgtbnL10.1385/NMM:8:4:531 CrinoPBTrojanowskiJQEberwineJInternexin, MAP1B, and nestin in cortical dysplasia as markers of developmental maturityActa Neuropathol1997936196271:CAS:528:DyaK2sXktVCmtr4%3D919490210.1007/s004010050660 LordCRisiSLambrechtLThe autism diagnostic observation schedule-generic: a standard measure of social and communication deficits associated with the spectrum of autismJ Autism Dev Disord2000302052231:STN:280:DC%2BD3crgsVOktA%3D%3D1105545710.1023/A:1005592401947 PierceKCourchesneEEvidence for a cerebellar role in reduced exploration and stereotyped behavior in autismBiol Psychiatry2001496556641:STN:280:DC%2BD3MzisFagsQ%3D%3D1131303310.1016/S0006-3223(00)01008-8 FalkaiPSchneider-AxmannTHonerWGEntorhinal cortex pre-alpha cell clusters in schizophrenia: quantitative evidence of a developmental abnormalityBiol Psychiatry2000479379431:STN:280:DC%2BD3c3pvVemuw%3D%3D1083806110.1016/S0006-3223(99)00250-4 Lopez-HurtadoEPrietoJJA microscopic study of language-related cortex in autismAm J Biochem Biotechnol2008413014510.3844/ajbbsp.2008.130.145 American Psychiatric AssociationDiagnostic and statistical manual of mental disorders DSM-IV-TR2000Washington, DCAmerican Psychiatric Association MadsenTMTreschowABengzonJBolwigTGLindvallOTingstromAIncreased neurogenesis in a model of electroconvulsive therapyBiol Psychiatry200047104310491:STN:280:DC%2BD3czit12ntQ%3D%3D1086280310.1016/S0006-3223(00)00228-6 CasanovaMFBuxhoevedenDPSwitalaAERoyEMinicolumnar pathology in autismNeurology20025842843211839843 HashimotoTTayamaMMiyazakiMMurakawaKKurodaYBrainstem and cerebellar vermis involvement in autistic childrenJ Child Neurol199381491531:STN:280:DyaK3s3otVequw%3D%3D850547710.1177/088307389300800207 HolttumJRMinshewNJSandersRSPhillipsNEMagnetic resonance imaging of the posterior fossa in autismBiol Psychiatry199232109111011:STN:280:DyaK3s7itVejtA%3D%3D147718910.1016/0006-3223(92)90189-7 SokolDKChenDFarlowMRHigh levels of Alzheimer beta-amyloid precursor protein (APP) in children with severely autistic behavior and aggressionJ Child Neurol20062144444916948926 WolfHKNormannSGreenAJTuberous sclerosis-like lesions in epileptogenic human neocortex lack allelic loss at the TSC1 and TSC2 regionsActa Neuropathol19979393961:STN:280:DyaK2s7lvFehsA%3D%3D900666210.1007/s004010050587 BoddaertNZilboviciusMPhilipeAMRI findings in 77 children with non-syndromic autistic disorderPLoS One20094e44151920479510.1371/journal.pone.00044151:CAS:528:DC%2BD1MXht1CltL7O ManevHUzTSmalheiserNRManevRAntidepressants alter cell proliferation in the adult brain in vivo and in neural cultures in vitroEur J Pharmacol200141167701:CAS:528:DC%2BD3MXht1Ghu7k%3D1113786010.1016/S0014-2999(00)00904-3 PivenJSalibaKBaileyJArndtSAn MRI study of autism: the cerebellum revisitedNeurology1997495465511:STN:280:DyaK2svhs1Kntg%3D%3D9270594 BaileyAPLuthertADeanBA clinicopathological study of autismBrain1998121889905961919210.1093/brain/121.5.889 WegielJWisniewskiTChauhanAChauhanAChauhanVBrownWTType, topography and sequelae of neuropathological changes shaping clinical phenotype of autismAutism: oxidative stress, inflammation, and immune abnormalities2010Boca Raton, FLTaylor & Francis/CRC Press134 RedcayECourchesneEWhen is the brain enlarged in autism? A meta-analysis of all brain size reportsBiol Psychiatry200558191593599310.1016/j.biopsych.2005.03.026 PoldrackRAPrabhakaranVSegerCAGabrieliJDStriatal activation during acquisition of a cognitive skillNeuropsychology1999135645741:STN:280:DyaK1MvlsVWruw%3D%3D1052706510.1037/0894-4105.13.4.564 GorlinJBHenskeEWarrenSTActin-binding protein (ABP-280) filamin gene (FLN) maps telomeric to the color vision locus (R/GCP) and centromer JG Gleeson (655_CR45) 1999; 23 K Volkmann (655_CR110) 2008; 313 RA Muller (655_CR81) 2007; 13 MR Herbert (655_CR54) 2003; 126 RA Poldrack (655_CR88) 1999; 13 V des Portes (655_CR29) 1998; 7 PB Crino (655_CR24) 1999; 53 J Townsend (655_CR104) 1999; 19 SH Fatemi (655_CR37) 2001; 12 A Lee (655_CR67) 2003; 53 E Lopez-Hurtado (655_CR68) 2008; 4 NS Harris (655_CR49) 1999; 8 TL Kemper (655_CR63) 1993; 11 RF Tuchman (655_CR105) 1991; 88 KC Ess (655_CR35) 2005; 64 G Chen (655_CR18) 2000; 75 K Pierce (655_CR86) 2001; 49 BS Chang (655_CR16) 2009 RF Tuchman (655_CR106) 2002; 1 C Lord (655_CR69) 2000; 30 A Matus (655_CR76) 1988; 11 LB Rorke (655_CR93) 1994; 53 SH Fatemi (655_CR38) 2001; 31 S Bruce (655_CR11) 2009; 46 P Falkai (655_CR36) 2000; 47 H Heinsen (655_CR53) 2000; 20 H Damasio (655_CR27) 1980; 37 655_CR62 S Kremer (655_CR65) 2002; 29 CJ Newschaffer (655_CR83) 2002; 24 M Rutter (655_CR94) 1994; 35 BL Jacobs (655_CR59) 1999; 21 MF Casanova (655_CR13) 2002; 58 PM Rodier (655_CR91) 1996; 370 J Avila (655_CR3) 1994; 38 SJ Palmen (655_CR85) 2004; 127 T Hashimoto (655_CR52) 1995; 25 M Marin-Padilla (655_CR74) 2002; 103 MF Mendez (655_CR78) 1989; 39 KT Ciesielski (655_CR20) 1997; 35 DM Andrade (655_CR2) 2009; 126 LB Rorke (655_CR92) 1968; 10 MP Kaplan (655_CR61) 1990; 10 MF Casanova (655_CR14) 2006; 112 LL Sears (655_CR99) 1999; 23 JH Miles (655_CR79) 2005; 135 W Murakami (655_CR82) 1989; 46 MG Nunzi (655_CR84) 2001; 434 WG Honer (655_CR57) 1996; 26 M Bobinski (655_CR9) 1999; 353 M Caspi (655_CR15) 2000; 9 M Ito (655_CR58) 2008; 9 JL Fuh (655_CR40) 1995; 97 LF Jarskog (655_CR60) 2000; 48 E Courchesne (655_CR22) 1988; 318 MR Diño (655_CR30) 1999; 28 F Happe (655_CR48) 2006; 9 ML Bauman (655_CR7) 1985; 35 PG Barth (655_CR6) 1987; 14 E Courchesne (655_CR21) 1987; 44 HB Sarnat (655_CR96) 1992; 69 M Baybis (655_CR8) 2004; 56 JG Gleeson (655_CR44) 1998; 92 ML Simms (655_CR100) 2009; 118 N Boddaert (655_CR10) 2009; 4 F Dubeau (655_CR31) 1995; 118 T Hashimoto (655_CR51) 1993; 8 JE Malberg (655_CR71) 2000; 20 J Piven (655_CR87) 1997; 49 A Guidotti (655_CR47) 2000; 57 AR Bailey (655_CR5) 2008; 1 L Tassi (655_CR102) 2002; 125 O Saitoh (655_CR95) 1998; 52 K Schmidtke (655_CR98) 2002; 9 JJ Yip (655_CR115) 2008; 86 C Gillberg (655_CR43) 1996; 38 TL Kemper (655_CR64) 1998; 57 H Miyata (655_CR80) 2004; 56 TW Chow (655_CR19) 1999 JR Holttum (655_CR56) 1992; 32 L Marcotte (655_CR73) 2006; 8 RS Duman (655_CR32) 2001; 25 E Hollander (655_CR55) 2005; 58 A Chauhan (655_CR17) 2006; 13 GR Gaffney (655_CR42) 1987; 141 PB Crino (655_CR25) 2002; 12 DK Sokol (655_CR101) 2006; 21 E Redcay (655_CR89) 2005; 58 HK Wolf (655_CR113) 1997; 93 655_CR28 RL Gabriels (655_CR41) 2005; 26 N Usui (655_CR107) 2001; 43 HJ Meencke (655_CR77) 1985; 26 BA Carlson (655_CR12) 1999 CR Marshall (655_CR75) 2008; 82 C Englund (655_CR34) 2006; 26 M Langen (655_CR66) 2007; 62 LA Weiss (655_CR112) 2009; 461 ER Ritvo (655_CR90) 1986; 143 PB Crino (655_CR23) 1997; 93 AP Bailey (655_CR4) 1998; 121 J Yip (655_CR114) 2007; 113 T Hashimoto (655_CR50) 1989; 20 GT Voelbel (655_CR109) 2006; 60 JW Fox (655_CR39) 1998; 21 J Wegiel (655_CR111) 2010 American Psychiatric Association (655_CR1) 2000 PS Eriksson (655_CR33) 1998; 4 JB Gorlin (655_CR46) 1993; 17 I Kooten van (655_CR108) 2008; 131 TM Madsen (655_CR70) 2000; 47 MA Curtis (655_CR26) 2005; 132 H Manev (655_CR72) 2001; 411 JD Schmahmann (655_CR97) 1999; 10 The Autism Genome Project Consortium (655_CR103) 2007; 39 |
| References_xml | – reference: FatemiSHStaryJMHalthARRealmutoGRDysregulation of reelin and Bcl-2 proteins in autistic cerebellumJ Autism Dev Disord2001315295351:STN:280:DC%2BD38%2Fos1yjtA%3D%3D1181426210.1023/A:1013234708757 – reference: GabrielsRLCuccaroMLHillDEIversBJGoldsonERepetitive behaviors in autism: relationships with associated clinical featuresRes Dev Disabil2005261691811559024710.1016/j.ridd.2004.05.003 – reference: MilesJHTakahashiTNBagbySEssential versus complex autism: definition of fundamental prognostic subtypesAm J Med Genet A20051351711801:STN:280:DC%2BD2M3ntlOqtg%3D%3D15887228 – reference: MarcotteLCrinoPBThe neurobiology of the tuberous sclerosis complexNeuromol Med200685315461:CAS:528:DC%2BD28XhtFCgtbnL10.1385/NMM:8:4:531 – reference: CiesielskiKTHarrisRJHartBLPabstHCerebellar hypoplasia and frontal lobe cognitive deficits in disorders of early childhoodNeuropsychologia1997356436551:STN:280:DyaK2s3pslGmug%3D%3D915302710.1016/S0028-3932(96)00119-4 – reference: BaybisMYuJLeeAGoldenJAmTOR cascade activation distinguishes tubers from focal cortical dysplasiaAnn Neurol2004564784871:CAS:528:DC%2BD2cXps1Kitrk%3D1545540510.1002/ana.20211 – reference: GorlinJBHenskeEWarrenSTActin-binding protein (ABP-280) filamin gene (FLN) maps telomeric to the color vision locus (R/GCP) and centromeric to G6PD in Xq28Genomics1993174964981:CAS:528:DyaK2cXht1Klsb0%3D840650110.1006/geno.1993.1354 – reference: BaileyAPLuthertADeanBA clinicopathological study of autismBrain1998121889905961919210.1093/brain/121.5.889 – reference: PierceKCourchesneEEvidence for a cerebellar role in reduced exploration and stereotyped behavior in autismBiol Psychiatry2001496556641:STN:280:DC%2BD3MzisFagsQ%3D%3D1131303310.1016/S0006-3223(00)01008-8 – reference: BaumanMLKemperTLHistoanatomic observations of the brain in early infantile autismNeurology1985358668671:STN:280:DyaL2M3hsVCnug%3D%3D4000488 – reference: FatemiSHKrollJLStaryJMAltered levels of Reelin and its isoforms in schizophrenia and mood disordersNeuroreport200112320932151:CAS:528:DC%2BD3MXotl2ju7c%3D1171185810.1097/00001756-200110290-00014 – reference: WeissLAArkingDEThe Gene Discovery Project of Johns Hopkins & the Autism ConsortiumA genome-wide linkage and association scan reveals novel loci for autismNature20094618028111:CAS:528:DC%2BD1MXht1CisLvI1981267310.1038/nature08490 – reference: HappeFRonaldAPlominRTime to give up on a single explanation for autismNat Neurosci20069121812201:CAS:528:DC%2BD28XhtVSgu7bF1700134010.1038/nn1770 – reference: HeinsenHArzbergerTSchmitzCCelloidin mounting (embedding without infiltration)—a new, simple and reliable method for producing serial sections of high thickness through complete human brains and its application to stereological and immunohistochemical investigationsJ Chem Neuroanat20002049591:STN:280:DC%2BD3M%2FotFShug%3D%3D1107434310.1016/S0891-0618(00)00067-3 – reference: YipJJSoghomonianJBlattGJIncreased GAD67 mRNA expression in cerebellar interneurons in autism: implications for Purkinje cell dysfunctionJ Neurosci Res2008865255301:CAS:528:DC%2BD1cXhvF2qsbo%3D1791874210.1002/jnr.21520 – reference: ChangBSWalshCARungeMSPattersonCThe genetic basis of human cerebral cortical malformationsPrinciples of molecular medicine2009Totowa, NJHuman Press Inc10731079 – reference: HashimotoTTayamaMMoriKFujinoKMiyazakiMKurodaYMagnetic resonance imaging in autism: preliminary reportNeuropediatrics1989201421461:STN:280:DyaL1MzosFSqsQ%3D%3D277974210.1055/s-2008-1071280 – reference: TuchmanRFRapinIEpilepsy in autismLancet Neurol200213523581284939610.1016/S1474-4422(02)00160-6 – reference: LeeAMaldonadoMBaybisMMarkers of cellular proliferation are expressed in cortical tubersAnn Neurol2003536686731:CAS:528:DC%2BD3sXktVSnt70%3D1273100310.1002/ana.10579 – reference: WolfHKNormannSGreenAJTuberous sclerosis-like lesions in epileptogenic human neocortex lack allelic loss at the TSC1 and TSC2 regionsActa Neuropathol19979393961:STN:280:DyaK2s7lvFehsA%3D%3D900666210.1007/s004010050587 – reference: ItoMControl of mental activities by internal models in the cerebellumNat Rev Neurosci200893043131:CAS:528:DC%2BD1cXjsFCks70%3D1831972710.1038/nrn2332 – reference: Marin-PadillaMParisiJEArmstrongDLSargentSKKaplanJAShaken infant syndrome: developmental neuropathology, progressive cortical dysplasia, and epilepsyActa Neuropathol20021033213321190475110.1007/s00401-001-0470-z – reference: Department of Health and Human Services (2007) Morbidity and mortality weekly report. In: Department of Health and Human Services, Centers for Disease Control and Prevention, pp 1–28 – reference: PoldrackRAPrabhakaranVSegerCAGabrieliJDStriatal activation during acquisition of a cognitive skillNeuropsychology1999135645741:STN:280:DyaK1MvlsVWruw%3D%3D1052706510.1037/0894-4105.13.4.564 – reference: RorkeLBFogelsonMHRiggsHECerebellar heterotopia in infancyDev Med Child Neurol1968106446501:STN:280:DyaF1M7gsVyjtw%3D%3D570828510.1111/j.1469-8749.1968.tb02951.x – reference: GuidottiAAutaJDavisJMDecrease in reelin and glutamic acid decarboxylase67 (GAD67) expression in schizophrenia and bipolar disorder: a postmortem brain studyArch Gen Psychiatry200057106110691:CAS:528:DC%2BD3cXot1WnsL0%3D1107487210.1001/archpsyc.57.11.1061 – reference: VoelbelGTBatesMEBuckmanJFPandinaGHendrenRLCaudate nucleus volume and cognitive performance: are they related in childhood psychopathology?Biol Psychiatry2006609429501695021210.1016/j.biopsych.2006.03.071 – reference: CasanovaMFvan KootenIAESwitalaEHMinicolumnar abnormalities in autismActa Neuropathol20061122873031681956110.1007/s00401-006-0085-5 – reference: DumanRSNakagawaSMalbergJRegulation of adult neurogenesis by antidepressant treatmentNeuropsychopharmacology2001258368441:CAS:528:DC%2BD3MXpt1antL8%3D1175017710.1016/S0893-133X(01)00358-X – reference: MatusAMicrotubule-associated proteins: their potential role in determining neuronal morphologyAnn Rev Neurosci19881129441:CAS:528:DyaL1cXhvVahtL4%3D328444410.1146/annurev.ne.11.030188.000333 – reference: des PortesVFrancisFPinardJMDoublecortin is the major gene causing X-linked subcortical laminar heterotopia (SCLH)Hum Mol Genet19987106310701:CAS:528:DyaK1cXktlKrs7g%3D961816210.1093/hmg/7.7.1063 – reference: FuhJLWangSJCaudate hemorrhage: clinical features, neuropsychological assessments and radiological findingsClin Neurol Neurosurg1995972962991:STN:280:DyaK287ntVOnsg%3D%3D859989510.1016/0303-8467(95)00059-S – reference: SearsLLVestCMohamedSBaileyJRansonBJPivenJAn MRI study of the basal ganglia in autismProg Neuropsychopharmacol Biol Psychiatry1999236136241:STN:280:DyaK1MzhvFWqsQ%3D%3D1039072010.1016/S0278-5846(99)00020-2 – reference: AvilaJDominguezJDiaz-NidoJRegulation of microtubule dynamics by microtubule-associated protein expression and phosphorylation during neuronal developmentInt J Dev Biol19943813251:CAS:528:DyaK2cXmslOit7s%3D8074993 – reference: CarlsonBAHouserOWGomezMRGomezMSampsonJWhittemoreVBrain imaging in the tuberous sclerosis complexTuberous sclerosis complex19993New YorkOxford University Press8593 – reference: PivenJSalibaKBaileyJArndtSAn MRI study of autism: the cerebellum revisitedNeurology1997495465511:STN:280:DyaK2svhs1Kntg%3D%3D9270594 – reference: KaplanMPChinSSFliegnerKHLiemRKAlpha-internexin, a novel neuronal intermediate filament protein, precedes the low molecular weight neurofilament protein (NF-L) in the developing rat brainJ Neurosci199010273527481:CAS:528:DyaK3cXmtVyrsb8%3D2201753 – reference: BaileyARGiuntaBNObregonDPeripheral biomarkers in autism: secreted amyloid precursor protein-alpha as a probable key player in early diagnosisInt J Clin Exp Med2008133834419079679 – reference: HashimotoTTayamaMMiyazakiMMurakawaKKurodaYBrainstem and cerebellar vermis involvement in autistic childrenJ Child Neurol199381491531:STN:280:DyaK3s3otVequw%3D%3D850547710.1177/088307389300800207 – reference: DiñoMRWillardFHMugnainiEDistribution of unipolar brush cells and other calretinin immunoreactive components in the mammalian cerebellar cortexJ Neurocytol199928991231059051110.1023/A:1007072105919 – reference: HarrisNSCourchesneETownsendJCarperRALordCNeuroanatomic contributions to slowed orienting of attention in children with autismBrain Res Cogn Brain Res1999861711:STN:280:DyaK1M3jtlymuw%3D%3D1021627410.1016/S0926-6410(99)00006-3 – reference: CrinoPBTrojanowskiJQEberwineJInternexin, MAP1B, and nestin in cortical dysplasia as markers of developmental maturityActa Neuropathol1997936196271:CAS:528:DyaK2sXktVCmtr4%3D919490210.1007/s004010050660 – reference: Kemper TL (1988) Neuroanatomic studies of dyslexia and autism. In: Disorders of the developing nervous system: changing views on their origins, diagnosis, and treatments. Alan R. Liss Inc, New York, pp 125–154 – reference: HolttumJRMinshewNJSandersRSPhillipsNEMagnetic resonance imaging of the posterior fossa in autismBiol Psychiatry199232109111011:STN:280:DyaK3s7itVejtA%3D%3D147718910.1016/0006-3223(92)90189-7 – reference: ChauhanAChauhanVOxidative stress in autismPathophysiology2006131711811:CAS:528:DC%2BD28XmslyqtLg%3D1676616310.1016/j.pathophys.2006.05.007 – reference: HonerWGBassettASFalkaiPBeachTGLapointeJSA case study of temporal lobe development in familial schizophreniaPsychol Med1996261911951:STN:280:DyaK283gs1OhtQ%3D%3D864375810.1017/S0033291700033821 – reference: TuchmanRFRapinIShinnarSAutistic and dysphasic children. I. Clinical characteristicsPediatrics199188121112181:STN:280:DyaK38%2Fms1Ciuw%3D%3D1956739 – reference: Lopez-HurtadoEPrietoJJA microscopic study of language-related cortex in autismAm J Biochem Biotechnol2008413014510.3844/ajbbsp.2008.130.145 – reference: ChenGRajkowskaGDuFSeraji-BozorgzadNManjiNHEnhancement of hippocampal neurogenesis by lithiumJ Neurochem200075172917341:CAS:528:DC%2BD3cXmslGltb0%3D1098785610.1046/j.1471-4159.2000.0751729.x – reference: RedcayECourchesneEWhen is the brain enlarged in autism? A meta-analysis of all brain size reportsBiol Psychiatry200558191593599310.1016/j.biopsych.2005.03.026 – reference: SarnatHBBenjaminDRSiebertJRCerebral dysgenesis: embryology and clinical expressionCell19926958159510.1016/0092-8674(92)90222-X – reference: HerbertMRZieglerDADeutschCKDissociations of cerebral cortex, subcortical and cerebral white matter volumes in autistic boysBrain2003126118211921:STN:280:DC%2BD3s3gvFyquw%3D%3D1269005710.1093/brain/awg110 – reference: MeenckeHJJanzDThe significance of microdysgenesia in primary generalized epilepsy: an answer to the considerations of Lyon and GastautEpilepsia1985263683711:STN:280:DyaL2M3jtVGitQ%3D%3D400689810.1111/j.1528-1157.1985.tb05665.x – reference: KremerSDe SaintMAMinottiLFocal cortical dysplasia possibly related to a probable prenatal ischemic injuryJ Neuroradiol2002292002031:STN:280:DC%2BD38novVGnsw%3D%3D12447145 – reference: RodierPMIngramJLTisdaleBNelsonSRomanoJEmbryological origin of autism: developmental abnormalities of the cranial nerve nucleiJ Comp Neurol19963702472611:STN:280:DyaK28vgsVGmsw%3D%3D880873310.1002/(SICI)1096-9861(19960624)370:2<247::AID-CNE8>3.0.CO;2-2 – reference: TassiLColomboNGarbelliRFocal cortical dysplasia: neuropathological subtypes, EEG, neuroimaging and surgical outcomeBrain2002125171917321:STN:280:DC%2BD38zoslWqsA%3D%3D1213596410.1093/brain/awf175 – reference: American Psychiatric AssociationDiagnostic and statistical manual of mental disorders DSM-IV-TR2000Washington, DCAmerican Psychiatric Association – reference: VolkmannKRiegerSBabarykaAKosterRWThe zebrafish cerebellar rhombic lip is spatially patterned in producing granule cell populations of different functional compartmentsDev Biol20083131671801:CAS:528:DC%2BD1cXhsVKqtg%3D%3D1803739910.1016/j.ydbio.2007.10.024 – reference: MalbergJEEischAJNestlerEJDumanRSChronic antidepressant treatment increases neurogenesis in adult rat hippocampusJ Neurosci200020910491101:CAS:528:DC%2BD3MXis1SqsA%3D%3D11124987 – reference: NewschafferCJFallinDLeeNLHeritable and nonheritable risk factors for autism spectrum disordersEpidemiol Rev2002241371531276208910.1093/epirev/mxf010 – reference: SchmidtkeKMannerHKaufmannRSchmolckHCognitive procedural learning in patients with fronto-striatal lesionsLearn Mem200294194291246470210.1101/lm.47202 – reference: MurakamiWCourchesneEPressGAYeung-CourchesneRHesselinkJRReduced cerebellar hemisphere size and its relationship to vermal hypoplasia in autismArch Neurol1989466896941:STN:280:DyaL1M3nt1Ohtg%3D%3D2730382 – reference: JacobsBLFornalCAActivity of serotonergic neurons in behaving animalsNeuropsychopharmacology1999219S15S1:CAS:528:DyaK1MXltVOnt7Y%3D10432483 – reference: BoddaertNZilboviciusMPhilipeAMRI findings in 77 children with non-syndromic autistic disorderPLoS One20094e44151920479510.1371/journal.pone.00044151:CAS:528:DC%2BD1MXht1CltL7O – reference: CaspiMAtlasRKantorASapirTReinerOInteraction between LIS1 and doublecortin, two lissencephaly gene productsHum Mol Genet20009220522131:CAS:528:DC%2BD3cXnt1ynt7c%3D11001923 – reference: ErikssonPSPerfilievaEBjork-ErikssonTNeurogenesis in the adult human hippocampusNat Med19984131313171:CAS:528:DyaK1cXntlaktb4%3D980955710.1038/3305 – reference: YipJSoghomonianJJBlattGJDecreased GAD67 mRNA levels in cerebellar Purkinje cells in autism: pathophysiological implicationsActa Neuropathol20071135595681:CAS:528:DC%2BD2sXks1ygtL0%3D1723551510.1007/s00401-006-0176-3 – reference: JarskogLFGilmoreJHSelingerESLiebermanJACortical bcl-2 protein expression and apoptotic regulation in schizophreniaBiol Psychiatry2000486416501:CAS:528:DC%2BD3cXntF2it7c%3D1103297510.1016/S0006-3223(00)00988-4 – reference: WegielJWisniewskiTChauhanAChauhanAChauhanVBrownWTType, topography and sequelae of neuropathological changes shaping clinical phenotype of autismAutism: oxidative stress, inflammation, and immune abnormalities2010Boca Raton, FLTaylor & Francis/CRC Press134 – reference: CourchesneEHesselinkJRJerniganTLYeung-CourchesneRAbnormal neuroanatomy in a nonretarded person with autism. Unusual findings with magnetic resonance imagingArch Neurol1987443353411:STN:280:DyaL2s7ls1WitQ%3D%3D3827686 – reference: GleesonJGLinPTFlanaganLAWalshCADoublecortin is a microtubule-associated protein and is expressed widely by migrating neuronsNeuron1999232572711:CAS:528:DyaK1MXks1Wrsrw%3D1039993310.1016/S0896-6273(00)80778-3 – reference: CasanovaMFBuxhoevedenDPSwitalaAERoyEMinicolumnar pathology in autismNeurology20025842843211839843 – reference: EnglundCKowalczykTDazaRAMUnipolar brush cells of the cerebellum are produced in the rhombic lip and migrate through developing white matterJ Neurosci200626918491951:CAS:528:DC%2BD28XpvFWqtb4%3D1695707510.1523/JNEUROSCI.1610-06.2006 – reference: CourchesneEYeung-CourchesneRPressGAHesselinkJRJerniganTLHypoplasia of cerebellar vermal lobules VI and VII in autismN Engl J Med1988318134913541:STN:280:DyaL1c3hs1Ojuw%3D%3D3367935 – reference: GillbergCColemanMAutism and medical disorders: a review of the literatureDev Med Child Neurol1996381912021:STN:280:DyaK283hsVGnsg%3D%3D863151610.1111/j.1469-8749.1996.tb15081.x – reference: SaitohOCourchesneEMagnetic resonance imaging study of the brain in autismPsychiatry Clin Neurosci199852SupplS219S2229895151 – reference: BobinskiMde LeonMJConvitAMRI of entorhinal cortex in mild Alzheimer’s diseaseLancet199935338401:STN:280:DyaK1M7ks1Glsg%3D%3D1002395510.1016/S0140-6736(05)74869-8 – reference: SokolDKChenDFarlowMRHigh levels of Alzheimer beta-amyloid precursor protein (APP) in children with severely autistic behavior and aggressionJ Child Neurol20062144444916948926 – reference: FoxJWLampertiEDEksiogluYZMutations in filamin 1 prevent migration of cerebral cortical neurons in human periventricular heterotopiaNeuron199821131513251:CAS:528:DyaK1MXntV2lug%3D%3D988372510.1016/S0896-6273(00)80651-0 – reference: MarshallCRNoorAVincentJBStructural variation of chromosomes in autism spectrum disorderAm J Human Gen2008824774881:CAS:528:DC%2BD1cXit1Sisrs%3D10.1016/j.ajhg.2007.12.009 – reference: AndradeDMGenetic basis in epilepsies caused by malformations of cortical development and in those with structurally normal brainHum Genet20091261731931953656510.1007/s00439-009-0702-1 – reference: LangenMDurstonSStaalWGPalmenSJvan EngelanHCaudate nucleus is enlarged in high-functioning medication-naive subjects with autismBiol Psychiatry2007622622661722413510.1016/j.biopsych.2006.09.040 – reference: SimmsMLKemperTLTimbieCMBaumanMLBlattGJThe anterior cingulate cortex in autism: heterogeneity of qualitative and quantitative cytoarchitectonic features suggests possible subgroupsActa Neuropathol20091186736841959088110.1007/s00401-009-0568-2 – reference: GaffneyGRTsaiLYKupermanSMinchinSCerebellar structure in autismAm J Dis Child1987141133013321:STN:280:DyaL1c%2FnsVWrsg%3D%3D3500635 – reference: EssKCKampCATuBPGutmannDHDevelopmental origin of subependymal giant cell astrocytoma in tuberous sclerosis complexNeurology2005641446144915851742 – reference: RitvoERFreemanBJScheibelABLower Purkinje cell counts in the cerebella of four autistic subjects: initial findings of the UCLA-NSAC Autopsy Research ReportAm J Psychiatry19861438628661:STN:280:DyaL283jvFOktw%3D%3D3717426 – reference: ManevHUzTSmalheiserNRManevRAntidepressants alter cell proliferation in the adult brain in vivo and in neural cultures in vitroEur J Pharmacol200141167701:CAS:528:DC%2BD3MXht1Ghu7k%3D1113786010.1016/S0014-2999(00)00904-3 – reference: CrinoPBMiyataHVintersHVNeurodevelopmental disorders as a cause of seizures: neuropathologic, genetic, and mechanistic considerationsBrain Pathol2002122122331:CAS:528:DC%2BD38XlvVSjtLk%3D1195837610.1111/j.1750-3639.2002.tb00437.x – reference: RorkeLBA perspective: the role of disordered genetic control of neurogenesis in the pathogenesis of migration disordersJ Neuropathol Exp Neurol1994531051171:STN:280:DyaK2c7msFKlsA%3D%3D812053510.1097/00005072-199403000-00001 – reference: MullerRAThe study of autism as a distributed disorderMent Retard Dev Disabil Res Rev20071385951732611810.1002/mrdd.20141 – reference: HashimotoTTayamaMMurakawaKDevelopment of the brainstem and cerebellum in autistic patientsJ Autism Dev Disord1995251181:STN:280:DyaK2Mzjt1WlsA%3D%3D760803010.1007/BF02178163 – reference: RutterMBaileyABoltonPLe CouteurAAutism and known medical conditions: myth and substanceJ Child Psychol Psychiatry1994353113221:STN:280:DyaK2c3ksFyrtg%3D%3D818880110.1111/j.1469-7610.1994.tb01164.x – reference: BruceSNybergFMelénEThe protective effect of farm animal exposure on childhood allergy is modified by NPSR1 polymorphismsJ Med Genet2009461591671:CAS:528:DC%2BD1MXktlKktb4%3D1828542810.1136/jmg.2007.055137 – reference: ChowTWCummingsJLMillerBLCummingsJLFrontal-subcortical circuitsThe human frontal lobes: functions and disorders1999New YorkGuilford Press326 – reference: MadsenTMTreschowABengzonJBolwigTGLindvallOTingstromAIncreased neurogenesis in a model of electroconvulsive therapyBiol Psychiatry200047104310491:STN:280:DC%2BD3czit12ntQ%3D%3D1086280310.1016/S0006-3223(00)00228-6 – reference: SchmahmannJDDoyonJMcDonaldDThree-dimensional MRI atlas of the human cerebellum in proportional stereotaxic spaceNeuroimage1999102332601:STN:280:DyaK1MzptVSlsw%3D%3D1045894010.1006/nimg.1999.0459 – reference: The Autism Genome Project ConsortiumMapping autism risk loci using genetic linkage and chromosomal rearrangementsNat Genet20073931932810.1038/ng19851:CAS:528:DC%2BD2sXitVOkt78%3D – reference: MiyataHChiangACVintersHInsulin signaling pathways in cortical dysplasia and TSC-tubers: tissue microarray analysisAnn Neurol2004565105191:CAS:528:DC%2BD2cXps1Kit74%3D1545539810.1002/ana.20234 – reference: BarthPGDisorders of neuronal migrationCan J Neurol Sci1987141161:STN:280:DyaL2s7jtVejtw%3D%3D3545413 – reference: KemperTLBaumanMLThe contribution of neuropathologic studies to the understanding of autismBehav Neurol1993111751871:STN:280:DyaK3s7otVOisQ%3D%3D – reference: DubeauFTampieriDLeeNPeriventricular and subcortical nodular heterotopia: a study of 33 patientsBrain199511812731287749678610.1093/brain/118.5.1273 – reference: CrinoPBHenskeEPNew developments in the neurobiology of the tuberous sclerosis complexNeurology199953138413901:STN:280:DC%2BD3c%2FgtFyjtA%3D%3D10534239 – reference: van KootenIPalmenSJvon EngelanCPNeurons in the fusiform gyrus are fewer and smaller in autismBrain20081319879991833207310.1093/brain/awn033 – reference: HollanderEAnagnostouEChaplinWStriatal volume on magnetic resonance imaging and repetitive behaviors in autismBiol Psychiatry2005582262321593940610.1016/j.biopsych.2005.03.040 – reference: TownsendJCourchesneECovingtonJSpatial attention deficits in patients with acquired or developmental cerebellar abnormalityJ Neurosci199919563256431:CAS:528:DyaK1MXktlyjsrY%3D10377369 – reference: NunziMGBirnstielSBhattacharyyaBJSlaterNTMugnainiEUnipolar brush cells form a glutamatergic projection system within the mouse cerebellar cortexJ Comp Neurol20014343293411:STN:280:DC%2BD3MzpsF2kug%3D%3D1133153210.1002/cne.1180 – reference: GleesonJGAllenKMFoxJWDoublecortin, a brain-specific gene mutated in human X-linked lissencephaly and double cortex syndrome, encodes a putative signaling proteinCell19989263721:CAS:528:DyaK1cXlt1egsA%3D%3D948970010.1016/S0092-8674(00)80899-5 – reference: LordCRisiSLambrechtLThe autism diagnostic observation schedule-generic: a standard measure of social and communication deficits associated with the spectrum of autismJ Autism Dev Disord2000302052231:STN:280:DC%2BD3crgsVOktA%3D%3D1105545710.1023/A:1005592401947 – reference: MendezMFAdamsNLLewandowskiKSNeurobehavioral changes associated with caudate lesionsNeurology1989393493541:STN:280:DyaL1M7ot1CktQ%3D%3D2927642 – reference: PalmenSJvan EngelanHHofPRSchmitzCNeuropathological findings in autismBrain2004127257225831532935310.1093/brain/awh287 – reference: DamasioHMaurerRGDamasioARChuiHCComputerized tomographic scan findings in patients with autistic behaviorArch Neurol1980375045101:STN:280:DyaL3M%2FitVKqsA%3D%3D6968201 – reference: UsuiNMatsudaKMiharaTMRI of cortical dysplasia-correlation with pathological findingsNeuroradiology2001438308371:STN:280:DC%2BD3Mnjs1Sqtw%3D%3D1168869810.1007/s002340100588 – reference: CurtisMAPenneyEBPearsonJDragunowMConnorBFaullRLThe distribution of progenitor cells in the subependymal layer of the lateral ventricle in the normal and Huntington’s disease human brainNeuroscience20051327777881:CAS:528:DC%2BD2MXjtlWru7g%3D1583713810.1016/j.neuroscience.2004.12.051 – reference: FalkaiPSchneider-AxmannTHonerWGEntorhinal cortex pre-alpha cell clusters in schizophrenia: quantitative evidence of a developmental abnormalityBiol Psychiatry2000479379431:STN:280:DC%2BD3c3pvVemuw%3D%3D1083806110.1016/S0006-3223(99)00250-4 – reference: KemperTLBaumanMNeuropathology of infantile autismJ Neuropathol Exp Neurol1998576456521:STN:280:DyaK1czlt12kug%3D%3D969066810.1097/00005072-199807000-00001 – volume: 35 start-page: 866 year: 1985 ident: 655_CR7 publication-title: Neurology doi: 10.1212/WNL.35.6.866 – volume: 4 start-page: e4415 year: 2009 ident: 655_CR10 publication-title: PLoS One doi: 10.1371/journal.pone.0004415 – volume: 38 start-page: 13 year: 1994 ident: 655_CR3 publication-title: Int J Dev Biol – volume: 318 start-page: 1349 year: 1988 ident: 655_CR22 publication-title: N Engl J Med doi: 10.1056/NEJM198805263182102 – volume: 37 start-page: 504 year: 1980 ident: 655_CR27 publication-title: Arch Neurol doi: 10.1001/archneur.1980.00500570052008 – volume: 53 start-page: 668 year: 2003 ident: 655_CR67 publication-title: Ann Neurol doi: 10.1002/ana.10579 – volume: 26 start-page: 169 year: 2005 ident: 655_CR41 publication-title: Res Dev Disabil doi: 10.1016/j.ridd.2004.05.003 – volume: 29 start-page: 200 year: 2002 ident: 655_CR65 publication-title: J Neuroradiol – volume: 53 start-page: 105 year: 1994 ident: 655_CR93 publication-title: J Neuropathol Exp Neurol doi: 10.1097/00005072-199403000-00001 – volume: 112 start-page: 287 year: 2006 ident: 655_CR14 publication-title: Acta Neuropathol doi: 10.1007/s00401-006-0085-5 – volume: 53 start-page: 1384 year: 1999 ident: 655_CR24 publication-title: Neurology doi: 10.1212/WNL.53.7.1384 – volume: 8 start-page: 531 year: 2006 ident: 655_CR73 publication-title: Neuromol Med doi: 10.1385/NMM:8:4:531 – volume: 48 start-page: 641 year: 2000 ident: 655_CR60 publication-title: Biol Psychiatry doi: 10.1016/S0006-3223(00)00988-4 – volume: 43 start-page: 830 year: 2001 ident: 655_CR107 publication-title: Neuroradiology doi: 10.1007/s002340100588 – volume: 461 start-page: 802 year: 2009 ident: 655_CR112 publication-title: Nature doi: 10.1038/nature08490 – volume: 13 start-page: 564 year: 1999 ident: 655_CR88 publication-title: Neuropsychology doi: 10.1037/0894-4105.13.4.564 – volume: 13 start-page: 85 year: 2007 ident: 655_CR81 publication-title: Ment Retard Dev Disabil Res Rev doi: 10.1002/mrdd.20141 – volume: 8 start-page: 149 year: 1993 ident: 655_CR51 publication-title: J Child Neurol doi: 10.1177/088307389300800207 – volume: 47 start-page: 1043 year: 2000 ident: 655_CR70 publication-title: Biol Psychiatry doi: 10.1016/S0006-3223(00)00228-6 – volume: 10 start-page: 644 year: 1968 ident: 655_CR92 publication-title: Dev Med Child Neurol doi: 10.1111/j.1469-8749.1968.tb02951.x – volume: 4 start-page: 1313 year: 1998 ident: 655_CR33 publication-title: Nat Med doi: 10.1038/3305 – volume: 118 start-page: 673 year: 2009 ident: 655_CR100 publication-title: Acta Neuropathol doi: 10.1007/s00401-009-0568-2 – volume: 20 start-page: 142 year: 1989 ident: 655_CR50 publication-title: Neuropediatrics doi: 10.1055/s-2008-1071280 – volume: 9 start-page: 304 year: 2008 ident: 655_CR58 publication-title: Nat Rev Neurosci doi: 10.1038/nrn2332 – volume: 93 start-page: 619 year: 1997 ident: 655_CR23 publication-title: Acta Neuropathol doi: 10.1007/s004010050660 – volume: 132 start-page: 777 year: 2005 ident: 655_CR26 publication-title: Neuroscience doi: 10.1016/j.neuroscience.2004.12.051 – ident: 655_CR28 – volume: 313 start-page: 167 year: 2008 ident: 655_CR110 publication-title: Dev Biol doi: 10.1016/j.ydbio.2007.10.024 – volume: 58 start-page: 428 year: 2002 ident: 655_CR13 publication-title: Neurology doi: 10.1212/WNL.58.3.428 – volume: 39 start-page: 349 year: 1989 ident: 655_CR78 publication-title: Neurology doi: 10.1212/WNL.39.3.349 – volume: 69 start-page: 581 year: 1992 ident: 655_CR96 publication-title: Cell doi: 10.1016/0092-8674(92)90222-X – volume: 25 start-page: 836 year: 2001 ident: 655_CR32 publication-title: Neuropsychopharmacology doi: 10.1016/S0893-133X(01)00358-X – volume: 125 start-page: 1719 year: 2002 ident: 655_CR102 publication-title: Brain doi: 10.1093/brain/awf175 – volume: 92 start-page: 63 year: 1998 ident: 655_CR44 publication-title: Cell doi: 10.1016/S0092-8674(00)80899-5 – volume: 103 start-page: 321 year: 2002 ident: 655_CR74 publication-title: Acta Neuropathol doi: 10.1007/s00401-001-0470-z – volume: 23 start-page: 613 year: 1999 ident: 655_CR99 publication-title: Prog Neuropsychopharmacol Biol Psychiatry doi: 10.1016/S0278-5846(99)00020-2 – volume: 44 start-page: 335 year: 1987 ident: 655_CR21 publication-title: Arch Neurol doi: 10.1001/archneur.1987.00520150073028 – volume: 97 start-page: 296 year: 1995 ident: 655_CR40 publication-title: Clin Neurol Neurosurg doi: 10.1016/0303-8467(95)00059-S – volume: 47 start-page: 937 year: 2000 ident: 655_CR36 publication-title: Biol Psychiatry doi: 10.1016/S0006-3223(99)00250-4 – volume: 17 start-page: 496 year: 1993 ident: 655_CR46 publication-title: Genomics doi: 10.1006/geno.1993.1354 – volume: 46 start-page: 689 year: 1989 ident: 655_CR82 publication-title: Arch Neurol doi: 10.1001/archneur.1989.00520420111032 – volume: 26 start-page: 191 year: 1996 ident: 655_CR57 publication-title: Psychol Med doi: 10.1017/S0033291700033821 – volume: 57 start-page: 1061 year: 2000 ident: 655_CR47 publication-title: Arch Gen Psychiatry doi: 10.1001/archpsyc.57.11.1061 – volume: 4 start-page: 130 year: 2008 ident: 655_CR68 publication-title: Am J Biochem Biotechnol doi: 10.3844/ajbbsp.2008.130.145 – volume: 12 start-page: 212 year: 2002 ident: 655_CR25 publication-title: Brain Pathol doi: 10.1111/j.1750-3639.2002.tb00437.x – volume: 135 start-page: 171 year: 2005 ident: 655_CR79 publication-title: Am J Med Genet A doi: 10.1002/ajmg.a.30590 – volume: 370 start-page: 247 year: 1996 ident: 655_CR91 publication-title: J Comp Neurol doi: 10.1002/(SICI)1096-9861(19960624)370:2<247::AID-CNE8>3.0.CO;2-2 – volume: 141 start-page: 1330 year: 1987 ident: 655_CR42 publication-title: Am J Dis Child – volume: 35 start-page: 311 year: 1994 ident: 655_CR94 publication-title: J Child Psychol Psychiatry doi: 10.1111/j.1469-7610.1994.tb01164.x – volume: 93 start-page: 93 year: 1997 ident: 655_CR113 publication-title: Acta Neuropathol doi: 10.1007/s004010050587 – volume: 26 start-page: 9184 year: 2006 ident: 655_CR34 publication-title: J Neurosci doi: 10.1523/JNEUROSCI.1610-06.2006 – volume: 21 start-page: 1315 year: 1998 ident: 655_CR39 publication-title: Neuron doi: 10.1016/S0896-6273(00)80651-0 – volume: 52 start-page: S219 issue: Suppl year: 1998 ident: 655_CR95 publication-title: Psychiatry Clin Neurosci doi: 10.1111/j.1440-1819.1998.tb03226.x – volume: 25 start-page: 1 year: 1995 ident: 655_CR52 publication-title: J Autism Dev Disord doi: 10.1007/BF02178163 – volume: 19 start-page: 5632 year: 1999 ident: 655_CR104 publication-title: J Neurosci doi: 10.1523/JNEUROSCI.19-13-05632.1999 – volume: 1 start-page: 352 year: 2002 ident: 655_CR106 publication-title: Lancet Neurol doi: 10.1016/S1474-4422(02)00160-6 – volume: 38 start-page: 191 year: 1996 ident: 655_CR43 publication-title: Dev Med Child Neurol doi: 10.1111/j.1469-8749.1996.tb15081.x – volume: 58 start-page: 1 year: 2005 ident: 655_CR89 publication-title: Biol Psychiatry doi: 10.1016/j.biopsych.2005.03.026 – volume: 11 start-page: 29 year: 1988 ident: 655_CR76 publication-title: Ann Rev Neurosci doi: 10.1146/annurev.ne.11.030188.000333 – volume: 14 start-page: 1 year: 1987 ident: 655_CR6 publication-title: Can J Neurol Sci doi: 10.1017/S031716710002610X – volume: 9 start-page: 419 year: 2002 ident: 655_CR98 publication-title: Learn Mem doi: 10.1101/lm.47202 – volume: 86 start-page: 525 year: 2008 ident: 655_CR115 publication-title: J Neurosci Res doi: 10.1002/jnr.21520 – volume: 20 start-page: 9104 year: 2000 ident: 655_CR71 publication-title: J Neurosci doi: 10.1523/JNEUROSCI.20-24-09104.2000 – volume: 57 start-page: 645 year: 1998 ident: 655_CR64 publication-title: J Neuropathol Exp Neurol doi: 10.1097/00005072-199807000-00001 – volume: 24 start-page: 137 year: 2002 ident: 655_CR83 publication-title: Epidemiol Rev doi: 10.1093/epirev/mxf010 – volume: 60 start-page: 942 year: 2006 ident: 655_CR109 publication-title: Biol Psychiatry doi: 10.1016/j.biopsych.2006.03.071 – volume: 121 start-page: 889 year: 1998 ident: 655_CR4 publication-title: Brain doi: 10.1093/brain/121.5.889 – volume: 49 start-page: 655 year: 2001 ident: 655_CR86 publication-title: Biol Psychiatry doi: 10.1016/S0006-3223(00)01008-8 – start-page: 3 volume-title: The human frontal lobes: functions and disorders year: 1999 ident: 655_CR19 – volume: 7 start-page: 1063 year: 1998 ident: 655_CR29 publication-title: Hum Mol Genet doi: 10.1093/hmg/7.7.1063 – volume: 58 start-page: 226 year: 2005 ident: 655_CR55 publication-title: Biol Psychiatry doi: 10.1016/j.biopsych.2005.03.040 – volume: 9 start-page: 1218 year: 2006 ident: 655_CR48 publication-title: Nat Neurosci doi: 10.1038/nn1770 – volume: 13 start-page: 171 year: 2006 ident: 655_CR17 publication-title: Pathophysiology doi: 10.1016/j.pathophys.2006.05.007 – volume: 23 start-page: 257 year: 1999 ident: 655_CR45 publication-title: Neuron doi: 10.1016/S0896-6273(00)80778-3 – volume: 126 start-page: 173 year: 2009 ident: 655_CR2 publication-title: Hum Genet doi: 10.1007/s00439-009-0702-1 – volume: 30 start-page: 205 year: 2000 ident: 655_CR69 publication-title: J Autism Dev Disord doi: 10.1023/A:1005592401947 – volume: 434 start-page: 329 year: 2001 ident: 655_CR84 publication-title: J Comp Neurol doi: 10.1002/cne.1180 – volume: 49 start-page: 546 year: 1997 ident: 655_CR87 publication-title: Neurology doi: 10.1212/WNL.49.2.546 – volume: 12 start-page: 3209 year: 2001 ident: 655_CR37 publication-title: Neuroreport doi: 10.1097/00001756-200110290-00014 – volume: 20 start-page: 49 year: 2000 ident: 655_CR53 publication-title: J Chem Neuroanat doi: 10.1016/S0891-0618(00)00067-3 – volume: 46 start-page: 159 year: 2009 ident: 655_CR11 publication-title: J Med Genet doi: 10.1136/jmg.2007.055137 – volume: 9 start-page: 2205 year: 2000 ident: 655_CR15 publication-title: Hum Mol Genet doi: 10.1093/oxfordjournals.hmg.a018911 – volume: 31 start-page: 529 year: 2001 ident: 655_CR38 publication-title: J Autism Dev Disord doi: 10.1023/A:1013234708757 – volume: 75 start-page: 1729 year: 2000 ident: 655_CR18 publication-title: J Neurochem doi: 10.1046/j.1471-4159.2000.0751729.x – volume-title: Diagnostic and statistical manual of mental disorders DSM-IV-TR year: 2000 ident: 655_CR1 – volume: 64 start-page: 1446 year: 2005 ident: 655_CR35 publication-title: Neurology doi: 10.1212/01.WNL.0000158653.81008.49 – volume: 127 start-page: 2572 year: 2004 ident: 655_CR85 publication-title: Brain doi: 10.1093/brain/awh287 – volume: 411 start-page: 67 year: 2001 ident: 655_CR72 publication-title: Eur J Pharmacol doi: 10.1016/S0014-2999(00)00904-3 – volume: 10 start-page: 2735 year: 1990 ident: 655_CR61 publication-title: J Neurosci doi: 10.1523/JNEUROSCI.10-08-02735.1990 – ident: 655_CR62 – volume: 56 start-page: 510 year: 2004 ident: 655_CR80 publication-title: Ann Neurol doi: 10.1002/ana.20234 – volume: 56 start-page: 478 year: 2004 ident: 655_CR8 publication-title: Ann Neurol doi: 10.1002/ana.20211 – volume: 8 start-page: 61 year: 1999 ident: 655_CR49 publication-title: Brain Res Cogn Brain Res doi: 10.1016/S0926-6410(99)00006-3 – volume: 10 start-page: 233 year: 1999 ident: 655_CR97 publication-title: Neuroimage doi: 10.1006/nimg.1999.0459 – volume: 126 start-page: 1182 year: 2003 ident: 655_CR54 publication-title: Brain doi: 10.1093/brain/awg110 – volume: 21 start-page: 9S year: 1999 ident: 655_CR59 publication-title: Neuropsychopharmacology doi: 10.1016/S0893-133X(99)00012-3 – volume: 62 start-page: 262 year: 2007 ident: 655_CR66 publication-title: Biol Psychiatry doi: 10.1016/j.biopsych.2006.09.040 – volume: 118 start-page: 1273 year: 1995 ident: 655_CR31 publication-title: Brain doi: 10.1093/brain/118.5.1273 – volume: 35 start-page: 643 year: 1997 ident: 655_CR20 publication-title: Neuropsychologia doi: 10.1016/S0028-3932(96)00119-4 – start-page: 1073 volume-title: Principles of molecular medicine year: 2009 ident: 655_CR16 – volume: 143 start-page: 862 year: 1986 ident: 655_CR90 publication-title: Am J Psychiatry doi: 10.1176/ajp.143.7.862 – volume: 88 start-page: 1211 year: 1991 ident: 655_CR105 publication-title: Pediatrics doi: 10.1542/peds.88.6.1211 – volume: 113 start-page: 559 year: 2007 ident: 655_CR114 publication-title: Acta Neuropathol doi: 10.1007/s00401-006-0176-3 – volume: 131 start-page: 987 year: 2008 ident: 655_CR108 publication-title: Brain doi: 10.1093/brain/awn033 – volume: 28 start-page: 99 year: 1999 ident: 655_CR30 publication-title: J Neurocytol doi: 10.1023/A:1007072105919 – volume: 353 start-page: 38 year: 1999 ident: 655_CR9 publication-title: Lancet doi: 10.1016/S0140-6736(05)74869-8 – volume: 32 start-page: 1091 year: 1992 ident: 655_CR56 publication-title: Biol Psychiatry doi: 10.1016/0006-3223(92)90189-7 – volume: 11 start-page: 175 year: 1993 ident: 655_CR63 publication-title: Behav Neurol – volume: 82 start-page: 477 year: 2008 ident: 655_CR75 publication-title: Am J Human Gen doi: 10.1016/j.ajhg.2007.12.009 – start-page: 1 volume-title: Autism: oxidative stress, inflammation, and immune abnormalities year: 2010 ident: 655_CR111 – volume: 26 start-page: 368 year: 1985 ident: 655_CR77 publication-title: Epilepsia doi: 10.1111/j.1528-1157.1985.tb05665.x – volume: 21 start-page: 444 year: 2006 ident: 655_CR101 publication-title: J Child Neurol doi: 10.1177/08830738060210062201 – start-page: 85 volume-title: Tuberous sclerosis complex year: 1999 ident: 655_CR12 doi: 10.1093/oso/9780195122107.003.0008 – volume: 1 start-page: 338 year: 2008 ident: 655_CR5 publication-title: Int J Clin Exp Med – volume: 39 start-page: 319 year: 2007 ident: 655_CR103 publication-title: Nat Genet doi: 10.1038/ng1985 |
| SSID | ssj0012745 |
| Score | 2.503301 |
| Snippet | Autism is characterized by a broad spectrum of clinical manifestations including qualitative impairments in social interactions and communication, and... |
| SourceID | pubmedcentral proquest pubmed crossref springer |
| SourceType | Open Access Repository Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 755 |
| SubjectTerms | Adolescent Adult Autism Autistic Disorder - complications Autistic Disorder - genetics Autistic Disorder - pathology Brain - growth & development Brain - pathology Case-Control Studies Cell Movement Child Child, Preschool Cohort Studies Female Humans Male Medicine Medicine & Public Health Middle Aged Neurogenesis Neurons - pathology Neurosciences Original Paper Pathology Young Adult |
| SummonAdditionalLinks | – databaseName: Health & Medical Collection dbid: 7X7 link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1NT9wwELX4kBCXilJKFyjygVPBIps4cdxLhaoihAQnkPYW2R6HrlSy22Y58O-ZsZOgLWKv9uw6yYztN57xPMZOTGagSOtMWF9mQqZKC-3ACgfEhVQiIEnp7vDNbXF1L68n-aTLzWm7tMp-TQwLNcwcnZGfo6NCdxkS_WP-VxBpFAVXOwaNdbZJlcsoo0tNBn9rjA5XJDBAj7lAw-2DmkmsIRr8aGJdyXMhl7elN1jzbcrkf3HTsB1d7rAPHY7kF1HxH9mab3bZ1k0XKf_EAPXPQ7FK4hwOZ-d8VnODdtY-fufgQxoHNQWhB1rypi03DcQG-vPH6UO0j7PQDs_tHLE2DsjjdeF2j91f_rr7eSU6RgXhELYtBO6IuUm0cjhvjazT2uoUAL9C7XxR1kqZDPEJ1AiDSpMW4DP0nS3KQ4pQwrvsM9toZo3_wrg2icszAG2VkUlpDaCvY1U9toUuILcjlvQftHJduXFivfhTDYWSgw4qHL0iHVRyxL4NP5nHWhurhA97LVXdtGurwUhGjA-9OF8oCGIaP3tqK0WXzBDDrRKRCPMQ9uAY-1Hrw-MgXNKlLLFHLdnDIEDVupd7munvULU7Je4vOR6x095yXp_73bc8WPmWh2w7JjPQodAR21j8e_JfESMt7HGYCS_f-w86 priority: 102 providerName: ProQuest |
| Title | The neuropathology of autism: defects of neurogenesis and neuronal migration, and dysplastic changes |
| URI | https://link.springer.com/article/10.1007/s00401-010-0655-4 https://www.ncbi.nlm.nih.gov/pubmed/20198484 https://www.proquest.com/docview/211862409 https://www.proquest.com/docview/733521599 https://www.proquest.com/docview/746152444 https://pubmed.ncbi.nlm.nih.gov/PMC2869041 |
| Volume | 119 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV1LT9wwEB4VkBAXBC2P5bHyoae2kYLjxDG3ZbUUtQJViJWWU2THDqwEWUSWA_-eGeeBFlqkniLZE9vxjONvPJ4ZgK860jbhRRQYl0aB4FIFKrcmyC3lQkoRkHDyHT6_SM7G4tcknjR-3FV72701Sfo_defsRvJGqi8lSonjQCzBSkyqOwrxmA860wGqWXXaAiROUFxbU-bfmljcjN4hzPcXJd9YS_0mdLoB6w16ZIOa3ZvwyZWfYfW8sY9_AYtcZz5EJWUa9ifmbFYwjdJV3R8z6_zlDSryRDf0o5tWTJe2LqDG76c3tVT88OX2uXpAhI0dstpJuNqC8enoangWNHkUghzB2jzAfTDWoZI5rlYtCl4Yxa3FWShyl6SFlDpCVGILBD-p5ol1EWrMBuktRwDh8mgblstZ6XaBKR3mcWStMlKLMDXaooZjZHFkEpXY2PQgbCc0y5sg45Tr4i7rwiN7HmTYe0Y8yEQPvnWvPNQRNj4i3m-5lDWLrcpQhyU3l1D1gHW1uErI9KFLN3uqMkmuZYjcPiIRCO4Q7GAfOzXXu-EgSFKpSLFGLshDR0Axuhdryumtj9XNKeOXOOrB91ZyXsf9z6_c-y_qfVirrzTQ0dABLM8fn9whIqW56cOSnMg-rAx-Xv8e4fNkdPHnEkuHybDvV80LFYYQ_w |
| linkProvider | Springer Nature |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1Lb9QwEB6VrQRcEG-W8vABLoBF6jgvJIR4tNrS7gqhVuot9SvtSm12IVuh_ij-IzN2ErRU7K1X24njzIznG49nBuCFipVNRRVz7fKYS5EVvDBWc2OpFlKOgERQ7PB4ko4O5NfD5HANfnexMHStstsT_UZtZ4bOyN-ioUKxDFHxYf6DU9Eocq52FTQCV-y6i19osTXvd74geV8Ksb21_3nE26IC3CByWXBUComKiswg6ypZiUoXwlq0Sirj0rzKMhWjirYVIoFcidS6GM1HjeOtQG3qTIzvvQbrMkZLZgDrn7Ym3773bgs08ULJBLTRUxSVzo0ahayl3nKnOi9JwuWyIryEbi9f0vzHU-sV4PZtuNUiV_YxsNodWHP1Xbg-bn3z98AixzGfHpOqHPvTejarmELObs7eMev8xRFq8oOOaZOdNkzVNjTQy8-mx4Ej3_h2e9HMEd3jhCwEKDf34eBKfvcDGNSz2j0CVqjIJLG1hc6UjHKtLFpXOqs2dVqkNtFDiLofWpo2wTnV2Tgt-9TMngYlzl4SDUo5hFf9I_OQ3WPV4I2OSmUr6E3Zs-UQWN-LEkpuF1W72XlTZhTWhqhx1RCJwBKBFs7xMFC9_xwEaEUuc-zJlvihH0D5wZd76umJzxMuqNqY3BzC645z_n73f1f5eOUqn8ON0f54r9zbmexuwM1wlYKOpJ7AYPHz3D1FhLbQz1q5YHB01aL4B4BfTis |
| linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1Lb9QwEB6VIlVcEO8u5eEDXICoWceJYySEEGXVUlpxoNLegh3bZSWaXchWqD-Nf8eMnQQtFXvr1XbiODNjf-N5ATzTmbYF91liXJklgkuVqNqapLZUC6lEQMIpdvjouNg_ER-n-XQDfvexMORW2e-JYaO285ruyHdRUaFYhlTt-s4r4vPe5O3iR0IFpMjQ2lfTiBxy6C5-ofbWvjnYQ1I_53zy4cv7_aQrMJDUiGKWCR4QuU6VrJGNtfDcG8WtRQ3F164ovZQ6w-PaekQFpeaFdRmqkgbHW44nq6szfO81uC6zfEwiJqeDrjdGZS8WT0BtvUCh6Q2qacxfGnR4qviS54lYPRIv4dzL7pr_2GzDUTi5BTc7DMveRaa7DRuuuQNbR52V_i5Y5D0WEmVSveNwb8_mnmnk8fbsNbMuuJBQUxh0StvtrGW6sbGBXn42O428-Sq024t2gTgfJ2QxVLm9BydX8rPvw2Yzb9w2MKXTOs-sVUZqkZZGW9SzjPRjU6jC5mYEaf9Dq7pLdU4VN75XQ5LmQIMKZ6-IBpUYwYvhkUXM87Fu8E5PpaoT-bYaGHQEbOhFWSUDjG7c_LytJAW4IX5cN0QgxETIhXM8iFQfPgehmipFiT1yhR-GAZQpfLWnmX0LGcM51R0T4xG87Dnn73f_d5UP167yKWyhAFafDo4Pd-BG9Kmgu6lHsLn8ee4eI1RbmidBKBh8vWop_ANaK1D7 |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=The+neuropathology+of+autism%3A+defects+of+neurogenesis+and+neuronal+migration%2C+and+dysplastic+changes&rft.jtitle=Acta+neuropathologica&rft.au=Wegiel%2C+Jerzy&rft.au=Kuchna%2C+Izabela&rft.au=Nowicki%2C+Krzysztof&rft.au=Imaki%2C+Humi&rft.date=2010-06-01&rft.pub=Springer-Verlag&rft.issn=0001-6322&rft.eissn=1432-0533&rft.volume=119&rft.issue=6&rft.spage=755&rft.epage=770&rft_id=info:doi/10.1007%2Fs00401-010-0655-4&rft.externalDocID=10_1007_s00401_010_0655_4 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0001-6322&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0001-6322&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0001-6322&client=summon |