Alpha proteobacterial ancestry of the [Fe-Fe]-hydrogenases in anaerobic eukaryotes

• Published in: Biology direct Vol. 11; no. 1; p. 34
• Main Authors: Degli Esposti, Mauro, Cortez, Diego, Lozano, Luis, Rasmussen, Simon, Nielsen, Henrik Bjørn, Martinez Romero, Esperanza
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 30.07.2016; BioMed Central
• Subjects: Alphaproteobacteria - genetics; Amino Acid Sequence; Bacterial Proteins - genetics; Discovery Notes; Eukaryotes; Evolution, Molecular; Gastrointestinal Microbiome - genetics; Humans; Hydrogenase - genetics; Phylogeny; Physiological aspects; Proteobacteria; Rhodospirillaceae - genetics; Anaerobic metabolism; Mitochondria; Bioenergetics; [FeFe]-hydrogenase; Eukaryogenesis

Eukaryogenesis, a major transition in evolution of life, originated from the symbiogenic fusion of an archaea with a metabolically versatile bacterium. By general consensus, the latter organism belonged to α proteobacteria, subsequently evolving into the mitochondrial organelle of our cells. The con...