Strategies for fighting pandemic virus infections: Integration of virology and drug delivery

Respiratory viruses have sometimes resulted in worldwide pandemics, with the influenza virus and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) being major participants. Long-term efforts have made it possible to control the influenza virus, but seasonal influenza continues to take man...

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Published inJournal of controlled release Vol. 343; pp. 361 - 378
Main Authors Nakamura, Takashi, Isoda, Norikazu, Sakoda, Yoshihiro, Harashima, Hideyoshi
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 01.03.2022
Subjects
Adjuvant
COVID-19 Drug Treatment
COVID-19 infection
Drug Delivery Systems
ecology
Humans
influenza
Influenza virus
Lipid-based nanocarrier
monitoring
nanocarriers
Orthomyxoviridae
pandemic
Pandemics - prevention & control
Respiratory virus infection
Review
SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2
Vaccine
Virology
Virus Diseases - epidemiology
viruses
SARS-CoV-2
Influenza virus
Respiratory virus infection
Lipid-based nanocarrier
Vaccine
Adjuvant
Virology
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Abstract Respiratory viruses have sometimes resulted in worldwide pandemics, with the influenza virus and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) being major participants. Long-term efforts have made it possible to control the influenza virus, but seasonal influenza continues to take many lives each year, and a pandemic influenza virus sometimes emerges. Although vaccines for coronavirus disease 2019 (COVID-19) have been developed, we are not yet able to coexist with the SARS-CoV-2. To overcome such viruses, it is necessary to obtain knowledge about international surveillance systems, virology, ecology and to determine that immune responses are effective. The information must then be transferred to drugs. Delivery systems would be expected to contribute to the rational development of drugs. In this review, virologist and drug delivery system (DDS) researchers discuss drug delivery strategies, especially the use of lipid-based nanocarriers, for fighting to respiratory virus infections. [Display omitted] •The virology and ecology of pandemic viruses are comprehensively reviewed.•Strategies that are jointly developed by virologists and DDS researchers.•Lipid nanoparticle mediated innate boosters for preventing unknown pandemic virus.•Potentially safe live artificial vaccines containing a universal antigen.
AbstractList Respiratory viruses have sometimes resulted in worldwide pandemics, with the influenza virus and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) being major participants. Long-term efforts have made it possible to control the influenza virus, but seasonal influenza continues to take many lives each year, and a pandemic influenza virus sometimes emerges. Although vaccines for coronavirus disease 2019 (COVID-19) have been developed, we are not yet able to coexist with the SARS-CoV-2. To overcome such viruses, it is necessary to obtain knowledge about international surveillance systems, virology, ecology and to determine that immune responses are effective. The information must then be transferred to drugs. Delivery systems would be expected to contribute to the rational development of drugs. In this review, virologist and drug delivery system (DDS) researchers discuss drug delivery strategies, especially the use of lipid-based nanocarriers, for fighting to respiratory virus infections.
Respiratory viruses have sometimes resulted in worldwide pandemics, with the influenza virus and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) being major participants. Long-term efforts have made it possible to control the influenza virus, but seasonal influenza continues to take many lives each year, and a pandemic influenza virus sometimes emerges. Although vaccines for coronavirus disease 2019 (COVID-19) have been developed, we are not yet able to coexist with the SARS-CoV-2. To overcome such viruses, it is necessary to obtain knowledge about international surveillance systems, virology, ecology and to determine that immune responses are effective. The information must then be transferred to drugs. Delivery systems would be expected to contribute to the rational development of drugs. In this review, virologist and drug delivery system (DDS) researchers discuss drug delivery strategies, especially the use of lipid-based nanocarriers, for fighting to respiratory virus infections. Unlabelled Image
Respiratory viruses have sometimes resulted in worldwide pandemics, with the influenza virus and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) being major participants. Long-term efforts have made it possible to control the influenza virus, but seasonal influenza continues to take many lives each year, and a pandemic influenza virus sometimes emerges. Although vaccines for coronavirus disease 2019 (COVID-19) have been developed, we are not yet able to coexist with the SARS-CoV-2. To overcome such viruses, it is necessary to obtain knowledge about international surveillance systems, virology, ecology and to determine that immune responses are effective. The information must then be transferred to drugs. Delivery systems would be expected to contribute to the rational development of drugs. In this review, virologist and drug delivery system (DDS) researchers discuss drug delivery strategies, especially the use of lipid-based nanocarriers, for fighting to respiratory virus infections.Respiratory viruses have sometimes resulted in worldwide pandemics, with the influenza virus and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) being major participants. Long-term efforts have made it possible to control the influenza virus, but seasonal influenza continues to take many lives each year, and a pandemic influenza virus sometimes emerges. Although vaccines for coronavirus disease 2019 (COVID-19) have been developed, we are not yet able to coexist with the SARS-CoV-2. To overcome such viruses, it is necessary to obtain knowledge about international surveillance systems, virology, ecology and to determine that immune responses are effective. The information must then be transferred to drugs. Delivery systems would be expected to contribute to the rational development of drugs. In this review, virologist and drug delivery system (DDS) researchers discuss drug delivery strategies, especially the use of lipid-based nanocarriers, for fighting to respiratory virus infections.
Respiratory viruses have sometimes resulted in worldwide pandemics, with the influenza virus and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) being major participants. Long-term efforts have made it possible to control the influenza virus, but seasonal influenza continues to take many lives each year, and a pandemic influenza virus sometimes emerges. Although vaccines for coronavirus disease 2019 (COVID-19) have been developed, we are not yet able to coexist with the SARS-CoV-2. To overcome such viruses, it is necessary to obtain knowledge about international surveillance systems, virology, ecology and to determine that immune responses are effective. The information must then be transferred to drugs. Delivery systems would be expected to contribute to the rational development of drugs. In this review, virologist and drug delivery system (DDS) researchers discuss drug delivery strategies, especially the use of lipid-based nanocarriers, for fighting to respiratory virus infections. [Display omitted] •The virology and ecology of pandemic viruses are comprehensively reviewed.•Strategies that are jointly developed by virologists and DDS researchers.•Lipid nanoparticle mediated innate boosters for preventing unknown pandemic virus.•Potentially safe live artificial vaccines containing a universal antigen.
Author Isoda, Norikazu
Nakamura, Takashi
Sakoda, Yoshihiro
Harashima, Hideyoshi
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  organization: Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-12, Nishi-6, Kita-ku, Sapporo 060-0812, Japan
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Keywords SARS-CoV-2
Influenza virus
Respiratory virus infection
Lipid-based nanocarrier
Vaccine
Adjuvant
Virology
Language English
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Drosten (10.1016/j.jconrel.2022.01.046_bb0570) 2014; 371
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Abd Elwakil (10.1016/j.jconrel.2022.01.046_bb0980) 2019; 29
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Dudek (10.1016/j.jconrel.2022.01.046_bb0695) 2006; 344
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Assiri (10.1016/j.jconrel.2022.01.046_bb0565) 2013; 369
Kastenmüller (10.1016/j.jconrel.2022.01.046_bb1255) 2014; 14
Mak (10.1016/j.jconrel.2022.01.046_bb0640) 2006
Channappanavar (10.1016/j.jconrel.2022.01.046_bb1075) 2019; 129
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Flerlage (10.1016/j.jconrel.2022.01.046_bb0900) 2021; 19
Beebe (10.1016/j.jconrel.2022.01.046_bb1020) 2002; 4
Hadjadj (10.1016/j.jconrel.2022.01.046_bb1065) 2020; 369
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Ge (10.1016/j.jconrel.2022.01.046_bb0500) 2015
De Clercq (10.1016/j.jconrel.2022.01.046_bb0740) 2005; 4
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Wang (10.1016/j.jconrel.2022.01.046_bb0820) 2020; 30
Cumulative number of confirmed human cases for avian influenza A(H5N1) reported to WHO, 2003–-2021 (10.1016/j.jconrel.2022.01.046_bb0215)
Bloom (10.1016/j.jconrel.2022.01.046_bb0280) 2010; 328
Wang (10.1016/j.jconrel.2022.01.046_bb0465) 2016; 31
Wu (10.1016/j.jconrel.2022.01.046_bb0345) 2020; 395
Lowery (10.1016/j.jconrel.2022.01.046_bb1040) 2021; 29
Cai (10.1016/j.jconrel.2022.01.046_bb0675) 2018; 149
Barber (10.1016/j.jconrel.2022.01.046_bb1105) 2015; 15
Hou (10.1016/j.jconrel.2022.01.046_bb0915) 2021; 6
Dagan (10.1016/j.jconrel.2022.01.046_bb0885) 2021; 384
Kempf (10.1016/j.jconrel.2022.01.046_bb0810) 1995; 92
Warashina (10.1016/j.jconrel.2022.01.046_bb0990) 2016; 225
Amouzegar (10.1016/j.jconrel.2022.01.046_bb1155) 2021; 13
Clark (10.1016/j.jconrel.2022.01.046_bb0330) 2014; 57
Bright (10.1016/j.jconrel.2022.01.046_bb0670) 2007; 25
Wei (10.1016/j.jconrel.2022.01.046_bb0850) 2020; 19
Robson (10.1016/j.jconrel.2022.01.046_bb0425) 2020; 79
Wang (10.1016/j.jconrel.2022.01.046_bb1205) 2018; 6
Tada (10.1016/j.jconrel.2022.01.046_bb1250) 2015; 10
Memish (10.1016/j.jconrel.2022.01.046_bb0575) 2014; 20
Xie (10.1016/j.jconrel.2022.01.046_bb0725) 2021; 27
Nakamura (10.1016/j.jconrel.2022.01.046_bb0935) 2013; 441
Furuta (10.1016/j.jconrel.2022.01.046_bb0315) 2005; 49
Nakamura (10.1016/j.jconrel.2022.01.046_bb0930) 2008; 16
Crooke (10.1016/j.jconrel.2022.01.046_bb1330) 2020; 10
Sette (10.1016/j.jconrel.2022.01.046_bb1325) 2021; 184
Zhou (10.1016/j.jconrel.2022.01.046_bb0480) 2020; 30
Xiao (10.1016/j.jconrel.2022.01.046_bb0495) 2020; 583
Lau (10.1016/j.jconrel.2022.01.046_bb0490) 2020; 26
Maeki (10.1016/j.jconrel.2022.01.046_bb1025) 2018; 128
Furuta (10.1016/j.jconrel.2022.01.046_bb0325) 2017; 93
Thoms (10.1016/j.jconrel.2022.01.046_bb0600) 2020; 369
Zheng (10.1016/j.jconrel.2022.01.046_bb0605) 2020; 5
Wang (10.1016/j.jconrel.2022.01.046_bb1165) 2020; 367
Tortorici (10.1016/j.jconrel.2022.01.046_bb0400) 2019; 105
Song (10.1016/j.jconrel.2022.01.046_bb0505) 2005; 102
Rawat (10.1016/j.jconrel.2022.01.046_bb0665) 2021; 892
Shirai (10.1016/j.jconrel.2022.01.046_bb0950) 2020; 8
Oberoi (10.1016/j.jconrel.2022.01.046_bb1230) 2016; 223
Pilkington (10.1016/j.jconrel.2022.01.046_bb1340) 2021; 131
Yasuda (10.1016/j.jconrel.2022.01.046_bb0150) 1993; 196
Fodor (10.1016/j.jconrel.2022.01.046_bb0130) 2004; 78
Tay (10.1016/j.jconrel.2022.01.046_bb0780) 2013; 99
Meyers (10.1016/j.jconrel.2022.01.046_bb0785) 2015; 218
Jiang (10.1016/j.jconrel.2022.01.046_bb1195) 202
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Snippet Respiratory viruses have sometimes resulted in worldwide pandemics, with the influenza virus and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)...
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SubjectTerms Adjuvant
COVID-19 Drug Treatment
COVID-19 infection
Drug Delivery Systems
ecology
Humans
influenza
Influenza virus
Lipid-based nanocarrier
monitoring
nanocarriers
Orthomyxoviridae
pandemic
Pandemics - prevention & control
Respiratory virus infection
Review
SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2
Vaccine
Virology
Virus Diseases - epidemiology
viruses
Title Strategies for fighting pandemic virus infections: Integration of virology and drug delivery
URI https://dx.doi.org/10.1016/j.jconrel.2022.01.046
https://www.ncbi.nlm.nih.gov/pubmed/35122872
https://www.proquest.com/docview/2626007279
https://www.proquest.com/docview/2648859216
https://pubmed.ncbi.nlm.nih.gov/PMC8810279
Volume 343
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