The role of surgical resection in the management of newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline

• Published in: Journal of neuro-oncology Vol. 96; no. 1; pp. 33 - 43
• Main Authors: Kalkanis, Steven N., Kondziolka, Douglas, Gaspar, Laurie E., Burri, Stuart H., Asher, Anthony L., Cobbs, Charles S., Ammirati, Mario, Robinson, Paula D., Andrews, David W., Loeffler, Jay S., McDermott, Michael, Mehta, Minesh P., Mikkelsen, Tom, Olson, Jeffrey J., Paleologos, Nina A., Patchell, Roy A., Ryken, Timothy C., Linskey, Mark E.
• Format: Journal Article
• Language: English
• Published: Boston Springer US 01.01.2010; Springer Nature B.V
• Subjects: Brain Neoplasms - diagnosis; Brain Neoplasms - radiotherapy; Brain Neoplasms - secondary; Brain Neoplasms - surgery; Evidence-Based Medicine; Humans; Invited Manuscript; Medicine; Medicine & Public Health; Neurology; Neurosurgery - methods; Neurosurgery - standards; Oncology; Practice Guidelines as Topic; Radiotherapy, Adjuvant - methods; Stereotactic radiosurgery; Practice guideline; Surgical resection; Systematic review; Brain metastases; Radiotherapy

Question Should patients with newly-diagnosed metastatic brain tumors undergo open surgical resection versus whole brain radiation therapy (WBRT) and/or other treatment modalities such as radiosurgery, and in what clinical settings? Target population These recommendations apply to adults with a newl...