Specificity of insulin signalling in human skeletal muscle as revealed by small interfering RNA - Krook, A; Zierath, J. R (Diabetologia, 2009)
Keywords: Biological and medical sciences; Diabetes; Diabetes Mellitus, Type 2; Diabetes Mellitus, Type 2 - genetics; Diabetes Mellitus, Type 2 - metabolism; Diabetes. Impaired glucose tolerance; Endocrine pancreas. Apud cells (diseases); Endocrinopathies; Enzymes; Etiopathogenesis. Screening. Investigations. Target tissue resistance; Fundamental and applied biological sciences. Psychology; Gene expression; Gene Expression - physiology; genetics; Glucose; Glucose metabolism; Homeostasis; Human Physiology; Humans; Insulin; Insulin - metabolism; Insulin resistance; Insulin signalling; Internal Medicine; Kinases; lipid metabolism; Lipids; Medical sciences; Medicine; Medicine & Public Health; Metabolic Diseases; Metabolism; Muscle, Skeletal; Muscle, Skeletal - physiology; Musculoskeletal system; Phosphorylation; Physiology; protein phosphorylation; Proteins; Review; RNA polymerase; RNA, Small Interfering; Signal Transduction; Signal Transduction - physiology; siRNA; skeletal muscle; Striated muscle. Tendons; Target validation; therapeutics; Vertebrates: osteoarticular system, musculoskeletal system; Glucose metabolism; Therapy; Target validation; siRNA; Insulin signalling; Lipid metabolism; Gene expression; Protein phosphorylation; Skeletal muscle; Endocrinopathy; Human; Pancreatic hormone; Phosphorylation; RNA; Diabetes mellitus; Lipids; Glucose; Striated muscle; Metabolism; Insulin; Protein; Specificity