The SAPHO Syndrome

• Published in: Seminars in arthritis and rheumatism Vol. 42; no. 3; pp. 254 - 265
• Main Authors: Nguyen, Minhchau Thi, Borchers, Andrea, Selmi, Carlo, Naguwa, Stanley M., Cheema, Gurtej, Gershwin, M. Eric
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.12.2012; Elsevier
• Subjects: acne; Acquired Hyperostosis Syndrome - diagnosis; Acquired Hyperostosis Syndrome - epidemiology; Acquired Hyperostosis Syndrome - genetics; Acquired Hyperostosis Syndrome - therapy; Adolescent; Adult; Aged; Analgesics - therapeutic use; Anti-Inflammatory Agents, Non-Steroidal - therapeutic use; Biological and medical sciences; Bullous diseases of the skin; Causality; Child; Child, Preschool; Dermatology; Diseases of the osteoarticular system; Drug Therapy, Combination; Female; Humans; hyperostosis; Male; Medical sciences; Middle Aged; osteitis; Pain - drug therapy; Pain Management; pustulosis; Rheumatology; Skin - pathology; Skin Diseases - pathology; Skin involvement in other diseases. Miscellaneous. General aspects; synovitis; Young Adult; hyperostosis; osteitis; acne; pustulosis; synovitis; Synovitis; Skin disease; Pustulosis dermatosis; Acne; Osteitis; Diseases of the osteoarticular system; Rheumatology; SAPHO syndrome; Pustulosis; Hyperostosis

To review the epidemiology, presentation, diagnosis, treatment, pathogenesis, and genetics of the syndrome known under the acronym of SAPHO for Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis to heighten awareness of this entity. We conducted a Medline search using SAPHO syndrome, chronic re...