Potential Nitrogen-Based Heterocyclic Compounds for Treating Infectious Diseases: A Literature Review

• Published in: Antibiotics (Basel) Vol. 11; no. 12; p. 1750
• Main Authors: Aatif, Mohammad, Raza, Muhammad Asam, Javed, Khadija, Nashre-Ul-Islam, Swah Mohd, Farhan, Mohd, Alam, Mir Waqas
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01.12.2022; MDPI
• Subjects: Antibacterial activity; Antibiotics; Bacteria; Chemical synthesis; Communicable diseases; Drug resistance; E coli; Gram-negative bacteria; heterocyclic compound; Heterocyclic compounds; in-vitro studies; infectious disease; Infectious diseases; Literature reviews; medicinal chemistry; Methicillin; Natural products; Nitrogen; Organic compounds; organic synthesis; Pharmaceuticals; Review; Staphylococcus infections; Strains (organisms); in-vitro studies; infectious disease; organic synthesis; medicinal chemistry; heterocyclic compound
• ISSN: 2079-6382; 2079-6382
• DOI: 10.3390/antibiotics11121750

Heterocyclic compounds are considered as one of the major and most diverse family of organic compounds. Nowadays, the demand for these compounds is increasing day-by-day due to their enormous synthetic and biological applications. These heterocyclic compounds have unique antibacterial activity against various Gram-positive and Gram-negative bacterial strains. This review covers the antibacterial activity of different heterocyclic compounds with nitrogen moiety. Some of the derivatives of these compounds show excellent antibacterial activity, while others show reasonable activity against bacterial strains. This review paper aims to bring and discuss the detailed information on the antibacterial activity of various nitrogen-based heterocyclic compounds. It will be helpful for the future evolution of diseases to synthesize new and effective drug molecules.