Regulation of membrane type-1 matrix metalloproteinase activity and intracellular localization in clinical thoracic aortic aneurysms - Ikonomidis, John S.; Nadeau, Elizabeth K.; Akerman, Adam W.; Stroud, Robert E.; Mukherjee, Rupak; Jones, Jeffrey A. (The Journal of thoracic and cardiovascular surgery, 2017)
Keywords: Aged; aneurysm; Animals; Aorta, Thoracic - enzymology; Aorta, Thoracic - pathology; Aortic Aneurysm, Thoracic - enzymology; Aortic Aneurysm, Thoracic - pathology; Cardiothoracic Surgery; Cell Line; Disease Models, Animal; Enzyme Activation - physiology; Fibroblasts - metabolism; Fibroblasts - pathology; Humans; Immunoblotting; Intracellular Space - enzymology; Matrix Metalloproteinase 14 - metabolism; Mice; Microscopy, Confocal; Middle Aged; MT1-MMP; protein kinase C; remodeling; thoracic aorta; Vascular Remodeling; PBS; aneurysm; remodeling; PMA; thoracic aorta; PKC; ECM; GFP; MMP; MT1-MMP; TGF; TAA; protein kinase C; phorbol 12-myristate 13-acetate; phosphate-buffered saline; green fluorescent protein; thoracic aortic aneurysm; membrane type-1 matrix metalloproteinase; matrix metalloproteinase; transforming growth factor; extracellular matrix