Cyclic stretch of embryonic cardiomyocytes increases proliferation, growth, and expression while repressing Tgf-β signaling - Banerjee, Indroneal; Carrion, Katrina; Serrano, Ricardo; Dyo, Jeffrey; Sasik, Roman; Lund, Sean; Willems, Erik; Aceves, Seema; Meili, Rudolph; Mercola, Mark; Chen, Ju; Zambon, Alexander; et al. (Journal of molecular and cellular cardiology, 2015)
Keywords: Animals; Cardiac development; Cardiomyocytes; Cardiovascular; Cell Proliferation - drug effects; Cell Size; Contractility; Embryo, Mammalian - cytology; Gene Expression Regulation - drug effects; Gene Ontology; Gene regulation; Hypoplastic Left Heart Syndrome; Mechanical stretch; Mice; Myocardial Contraction - drug effects; Myocytes, Cardiac - cytology; Myocytes, Cardiac - drug effects; Myocytes, Cardiac - metabolism; Myofibrils - metabolism; Sequence Analysis, RNA; Signal Transduction - drug effects; Stress, Mechanical; Transforming Growth Factor beta - metabolism; Transforming Growth Factor beta - pharmacology; SSC; Other myocardial biology; Gene regulation; Contractile function; Contractility; GO; Cardiomyocytes; Cardiac development; Pediatric and congenital heart disease; HLHS; DMFM; Cell biology/structural biology; RNA-Seq; FDR; Subject Codes; Mechanical stretch; EdU; Hypoplastic Left Heart Syndrome; qPCR; Physiologic and pathologic control of gene expression; Gene ontology; mRNA-sequencing; 5-ethynyl-2′-deoxyuridine; Dynamic monolayer force microscopy; Quantitative Real Time PCR; False discovery rate; Flow cytometry side scatter